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Results for “Locally Advanced Leiomyosarcoma”

20 trials

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Showing 20 of 20 results

Early research (Phase 1)Study completedNCT03009201
What this trial is testing

Ribociclib and Doxorubicin in Treating Patients With Metastatic or Advanced Soft Tissue Sarcomas That Cannot Be Removed by Surgery

Who this might be right for
Advanced Soft Tissue SarcomaLocally Advanced AngiosarcomaLocally Advanced Leiomyosarcoma+24 more
OHSU Knight Cancer Institute 16
Early research (Phase 1)Active Not RecruitingNCT05827614
What this trial is testing

Study of the CHK1 Inhibitor BBI-355, an ecDNA-directed Therapy (ecDTx), and the RNR Inhibitor BBI-825, in Subjects With Tumors With Oncogene Amplifications

Who this might be right for
Triple Negative Breast Cancer (TNBC)High Grade Serous Ovarian CarcinomaHigh Grade Endometrial Carcinoma+9 more
Boundless Bio 85
Early research (Phase 1)Study completedNCT00720174
What this trial is testing

Cixutumumab and Doxorubicin Hydrochloride in Treating Patients With Unresectable, Locally Advanced, or Metastatic Soft Tissue Sarcoma

Who this might be right for
Adult AngiosarcomaAdult Desmoplastic Small Round Cell TumorAdult Epithelioid Sarcoma+32 more
National Cancer Institute (NCI) 30
Testing effectiveness (Phase 2)Study completedNCT00041249
What this trial is testing

Brostallicin in Treating Patients With Locally Advanced or Metastatic Soft Tissue Sarcoma

Who this might be right for
Gastrointestinal Stromal TumorSarcoma
European Organisation for Research and Treatment of Cancer - EORTC 64
Testing effectiveness (Phase 2)Ended earlyNCT02601209
What this trial is testing

Sapanisertib or Pazopanib Hydrochloride in Treating Patients With Locally Advanced or Metastatic Sarcoma

Who this might be right for
High Grade SarcomaMetastatic LeiomyosarcomaMetastatic Malignant Peripheral Nerve Sheath Tumor+16 more
National Cancer Institute (NCI) 151
Large-scale testing (Phase 3)Study completedNCT00061984
What this trial is testing

Doxorubicin With or Without Ifosfamide and Pegfilgrastim in Treating Patients With Locally Advanced or Metastatic Soft Tissue Sarcoma

Who this might be right for
Sarcoma
European Organisation for Research and Treatment of Cancer - EORTC 455
Testing effectiveness (Phase 2)Study completedNCT00659360
What this trial is testing

AZD0530 in Treating Patients With Recurrent Locally Advanced or Metastatic Soft Tissue Sarcoma

Who this might be right for
Adult FibrosarcomaAdult LeiomyosarcomaAdult Liposarcoma+12 more
National Cancer Institute (NCI) 17
Testing effectiveness (Phase 2)Study completedNCT00060944
What this trial is testing

Assess Treatment With 2 Different Dosing Schedules of Trabectidin Administered to Patients With Advanced Cancer

Who this might be right for
LiposarcomaLeiomyosarcoma
Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 271
Early research (Phase 1)Study completedNCT03761095
What this trial is testing

Unesbulin (PTC596) in Combination With Dacarbazine in Participants With Advanced Leiomyosarcoma (LMS)

Who this might be right for
Leiomyosarcoma
PTC Therapeutics 41
Testing effectiveness (Phase 2)Study completedNCT00053794
What this trial is testing

Perifosine in Treating Patients With Metastatic or Locally Advanced Soft Tissue Sarcoma

Who this might be right for
Endometrial CancerSarcoma
NCIC Clinical Trials Group 17
Testing effectiveness (Phase 2)Study completedNCT00390234
What this trial is testing

Ziv-aflibercept in Treating Patients With Locally Advanced, Unresectable, or Metastatic Gynecologic Soft Tissue Sarcoma

Who this might be right for
Fallopian Tube CancerFemale Reproductive CancerOvarian Carcinosarcoma+9 more
National Cancer Institute (NCI) 63
Testing effectiveness (Phase 2)Active Not RecruitingNCT05836571
What this trial is testing

Testing Ipilimumab and Nivolumab Combination With or Without Cabozantinib in People >= 18 Years Old With Advanced Soft Tissue Sarcoma

Who this might be right for
Locally Advanced Extraskeletal Myxoid ChondrosarcomaLocally Advanced LeiomyosarcomaLocally Advanced Liposarcoma+7 more
National Cancer Institute LAO 66
Testing effectiveness (Phase 2)Ended earlyNCT04171700
What this trial is testing

Evaluate Rucaparib in Participants With Solid Tumors and With Deleterious Mutations in HRR Genes

Who this might be right for
Solid Tumor
pharmaand GmbH 83
Large-scale testing (Phase 3)Study completedNCT01692678
What this trial is testing

Trabectedin (YONDELIS) in Patients With Locally Advanced or Metastatic Liposarcoma or Leiomyosarcoma

Who this might be right for
Advanced or Metastatic Liposarcoma or Leiomyosarcoma
Xian-Janssen Pharmaceutical Ltd. 16
Large-scale testing (Phase 3)Active Not RecruitingNCT05432791
What this trial is testing

Testing Olaparib and Temozolomide Versus the Usual Treatment for Uterine Leiomyosarcoma After Chemotherapy Has Stopped Working

Who this might be right for
Locally Advanced Uterine Corpus LeiomyosarcomaMetastatic Uterine Corpus LeiomyosarcomaStage III Uterine Corpus Leiomyosarcoma AJCC v8+2 more
National Cancer Institute (NCI) 73
Testing effectiveness (Phase 2)WithdrawnNCT05174455
What this trial is testing

Niraparib for the Treatment of Leiomyosarcoma

Who this might be right for
Locally Advanced LeiomyosarcomaMetastatic LeiomyosarcomaStage III Retroperitoneal Sarcoma AJCC v8+4 more
David Liebner, MD
Testing effectiveness (Phase 2)UnknownNCT00033709
What this trial is testing

Temozolomide and Thalidomide in Treating Patients With Metastatic, Locally Advanced, or Unresectable Leiomyosarcoma

Who this might be right for
Sarcoma
Herbert Irving Comprehensive Cancer Center
Testing effectiveness (Phase 2)Study completedNCT00245102
What this trial is testing

Sorafenib in Treating Patients With Metastatic, Locally Advanced, or Recurrent Sarcoma

Who this might be right for
Adult AngiosarcomaAdult Epithelioid SarcomaAdult Leiomyosarcoma+12 more
National Cancer Institute (NCI) 147
Testing effectiveness (Phase 2)Study completedNCT00474994
What this trial is testing

Sunitinib in Treating Patients With Metastatic, Locally Advanced, or Locally Recurrent Sarcomas

Who this might be right for
Adult Malignant Fibrous Histiocytoma of BoneDesmoid TumorEndometrial Cancer+3 more
Memorial Sloan Kettering Cancer Center 53
Testing effectiveness (Phase 2)Looking for participantsNCT04383119
What this trial is testing

Trial in Patients With Metastatic or Locally Advanced Leiomyosarcoma

Who this might be right for
Leiomyosarcoma of OvarySoft Tissue Sarcoma
Italian Sarcoma Group 100