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Results for “Locally Advanced Rectal Cancer”

681 trials

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Showing 20 of 681 results

Not applicableActive Not RecruitingNCT02874885
What this trial is testing

Circulating Tumor Cells in Patients With Locally Advanced Rectal Cancer

Who this might be right for
Locally Advanced Rectal AdenocarcinomaMetastatic Rectal AdenocarcinomaRectosigmoid Adenocarcinoma+10 more
M.D. Anderson Cancer Center 341
Testing effectiveness (Phase 2)Ended earlyNCT04171700
What this trial is testing

Evaluate Rucaparib in Participants With Solid Tumors and With Deleterious Mutations in HRR Genes

Who this might be right for
Solid Tumor
pharmaand GmbH 83
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07243938
What this trial is testing

Phase II Basket Trial: Zanidatamab Plus Tislelizumab in HER2-Positive GI Tumors (UNION-HER2-BASKET)

Who this might be right for
Locally Advanced Rectal Cancer (LARC)Locally Advanced Gastric/Gastroesophageal Junction AdenocarcinomaMetastatic Colorectal Cancer (mCRC)+1 more
Tao Zhang 70
Testing effectiveness (Phase 2)Active Not RecruitingNCT06056804
What this trial is testing

Neoadjuvant Chemoradiotherapy Combined With PD-1 Inhibitor and Thymalfasin for pMMR/MSS Locally Advanced Mid-low Rectal Cancer

Who this might be right for
Locally Advanced Rectal Cancer
Beijing Friendship Hospital 20
Early research (Phase 1)Study completedNCT05954871
What this trial is testing

Study to Evaluate the Safety, Pharmacokinetics, and Activity of GDC-1971 in Combination With Either Osimertinib in Participants With Unresectable, Locally Advanced, or Metastatic Non-Small Cell Lung Cancer, or With Cetuximab in Participants With Metastatic Colorectal Cancer

Who this might be right for
Colorectal CancerNon-Small Cell Lung Cancer
Genentech, Inc. 10
Testing effectiveness (Phase 2)Looking for participantsNCT05972655
What this trial is testing

Nodes-sparing Short-course Radiation Combined With CAPOX and Tislelizumab for MSS Middle and Low Rectal Cancer

Who this might be right for
Low Rectal Cancer
Sir Run Run Shaw Hospital 32
Testing effectiveness (Phase 2)Study completedNCT05316818
What this trial is testing

Triplet (FOLFOXIRI) vs. Doublet (FOLFOX or FOLFIRI) Regimen as a 1st Line Treatment in Metastatic Colorectal Carcinoma

Who this might be right for
Metastatic Colorectal Cancer
Kasr El Aini Hospital 64
Large-scale testing (Phase 3)Looking for participantsNCT06312982
What this trial is testing

A Series of Neoadjuvant Chemoradiotherapy Combined With Immunotherapy for Locally Advanced Rectal Cancer

Who this might be right for
Locally Advanced Rectal Carcinoma
Beijing Friendship Hospital 375
Testing effectiveness (Phase 2)UnknownNCT02948348
What this trial is testing

Study to Nivolumab Following Preoperative Chemoradiotherapy

Who this might be right for
Cancer of Rectum
Takayuki Yoshino 90
Not applicableStudy completedNCT06982053
What this trial is testing

[68Ga]Ga-GZP PET for Early Response Prediction in Colorectal Cancer During Neoadjuvant Therapy

Who this might be right for
Colorectal Cancer Control and PreventionColorectal Cancer RecurrentColorectal Cancer Metastatic+1 more
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 21
Testing effectiveness (Phase 2)WithdrawnNCT00070434
What this trial is testing

S0304 Induct Chemo Then Chemo-RT in Pts w/Locally Advanced Adenocarcinoma of the Rectum

Who this might be right for
Colorectal Cancer
SWOG Cancer Research Network
Testing effectiveness (Phase 2)Looking for participantsNCT07154316
What this trial is testing

Phase II RCT of LCRT vs SCRT + CAPOX/PD-1i/COX-2i in MSS Locally Advanced Rectal Cancer

Who this might be right for
Colorectal Cancer
Fudan University 138
Testing effectiveness (Phase 2)Not Yet RecruitingNCT05969847
What this trial is testing

Organ Preservation Following Enverolimab-based Total Neoadjuvant Therapy for Locally Advanced Very Low Rectal Cancer

Who this might be right for
Rectal Cancer
池畔 72
Not applicableUnknownNCT03577808
What this trial is testing

Organoids in Predicting Chemoradiation Sensitivity on Rectal Cancer

Who this might be right for
OrganoidsRectal CancerChemoradiation
Zhen Zhang 80
Testing effectiveness (Phase 2)Study completedNCT00081289
What this trial is testing

Neoadjuvant Chemoradiotherapy and Adjuvant Chemotherapy in Treating Patients Who Are Undergoing Surgical Resection for Locally Advanced Rectal Cancer

Who this might be right for
Colorectal Cancer
Radiation Therapy Oncology Group 146
Testing effectiveness (Phase 2)Looking for participantsNCT04585750
What this trial is testing

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

Who this might be right for
Advanced Solid TumorAdvanced Malignant NeoplasmMetastatic Cancer+27 more
PMV Pharmaceuticals, Inc 300
Large-scale testing (Phase 3)Study completedNCT00427713
What this trial is testing

Capecitabine and Oxaliplatin or Standard Follow-Up Care in Treating Patients Who Have Undergone Surgery for Locally Advanced Rectal Cancer

Who this might be right for
Colorectal Cancer
Cancer Research UK 800
Not applicableStudy completedNCT06879197
What this trial is testing

Clinical Relevance of Major Pathologic Regression for Locally Advanced Rectal Cancer

Who this might be right for
Rectal NeoplasmsChemotherapy Effect
Yanhong Deng 1,187
Testing effectiveness (Phase 2)Study completedNCT00118755
What this trial is testing

Two Different Schedules of Xeloda (Capecitabine) as First Line Therapy in Patients With Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer
Hoffmann-La Roche 435
Testing effectiveness (Phase 2)UnknownNCT02560298
What this trial is testing

Cisplatin and Fluorouracil Compared With Carboplatin and Paclitaxel in Treating Patients With Inoperable Locally Recurrent or Metastatic Anal Cancer

Who this might be right for
Anal Basaloid CarcinomaAnal Canal Cloacogenic CarcinomaAnal Squamous Cell Carcinoma+4 more
ECOG-ACRIN Cancer Research Group 91
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