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Results for “Locally Advanced Rectal Carcinoma”

664 trials

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Showing 20 of 664 results

Testing effectiveness (Phase 2)Study completedNCT00613080
What this trial is testing

Combination Chemotherapy and Intensity-Modulated Radiation Therapy in Treating Patients Undergoing Surgery for Locally Advanced Rectal Cancer

Who this might be right for
Colorectal Cancer
Radiation Therapy Oncology Group 79
Testing effectiveness (Phase 2)Study completedNCT03443661
What this trial is testing

Neoadjuvant Triplet Chemotherapy Regimen in Patients With Locally Advanced Rectal Cancer

Who this might be right for
Locally Advanced Rectal Cancer
Aiping Zhou 50
Not applicableUnknownNCT04273477
What this trial is testing

Radiomics-based Artificial Intelligence System to Predict Neoadjuvant Treatment Response in Rectal Cancer

Who this might be right for
Rectal Cancer
Sixth Affiliated Hospital, Sun Yat-sen University 100
Testing effectiveness (Phase 2)Ended earlyNCT05091528
What this trial is testing

A Safety and Activity Study of SBT6050 in Combination With Other HER2-directed Therapies for HER2-positive Cancers

Who this might be right for
HER2-positive Breast CancerHER2-positive Gastric CancerHER2-positive Colorectal Cancer+1 more
Silverback Therapeutics 2
Testing effectiveness (Phase 2)Looking for participantsNCT07433673
What this trial is testing

Gemcitabine, Cisplatin, Nab-paclitaxel (GAP) and Cemiplimab for Locally Advanced Biliary Tract Cancer (BTC)

Who this might be right for
Colon and Rectal Cancer
Columbia University 20
Large-scale testing (Phase 3)UnknownNCT01459328
What this trial is testing

Resource-Sparing Curative Treatment for Rectal Cancer

Who this might be right for
Rectal Carcinoma
International Atomic Energy Agency 350
Testing effectiveness (Phase 2)UnknownNCT06239870
What this trial is testing

Single-arm, Single-center, Exploratory Phase II Clinical Study of Envafolimab Combined With Chemoradiotherapy in the Treatment of Locally Advanced pMMR/MSS Rectal Cancer

Who this might be right for
Envafolimab Combined With Chemoradiotherapy in the Treatment of Locally Advanced pMMR/MSS Rectal Cancer
Yunnan Cancer Hospital 35
Testing effectiveness (Phase 2)Looking for participantsNCT05592626
What this trial is testing

A Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors

Who this might be right for
Advanced Solid TumorsGenital Neoplasm, FemaleUrogenital Neoplasms+11 more
Marengo Therapeutics, Inc. 366
Not applicableStudy completedNCT01914068
What this trial is testing

The Effects of a 9 Week Exercise Programme on Fitness and Quality of Life in Rectal Cancer Patients After Chemoradiotherapy and Before Surgery

Who this might be right for
Rectal Cancer
University Hospital Southampton NHS Foundation Trust 34
Large-scale testing (Phase 3)Not Yet RecruitingNCT07686796
What this trial is testing

Anti-PCSK9 Antibody Tafolecimab and Anti-PD-1 Antibody Sintilimab Combined With Neoadjuvant Chemoradiotherapy for pMMR/ MSS Locally Advanced Rectal Cancer : A Prospective, Multicenter, Randomized, Open-Label, Parallel-Controlled Trial

Who this might be right for
Local Advanced Rectal CancerPD-1 InhibitorPCSK9 Inhibitor+4 more
Guangdong Provincial People's Hospital 148
Testing effectiveness (Phase 2)Looking for participantsNCT05731726
What this trial is testing

Serplulimab Combined With CAPEOX + Celecoxib as Neoadjuvant Treatment for Locally Advanced Rectal Cancer

Who this might be right for
pMMRMSSMSI-L+1 more
Zhejiang University 50
Large-scale testing (Phase 3)Looking for participantsNCT06997497
What this trial is testing

A Clinical Study of Calderasib (MK-1084) With Targeted Therapy and Chemotherapy in People With Colorectal Cancer (MK-1084-012/KANDLELIT-012)

Who this might be right for
Colon AdenocarcinomaRectal Adenocarcinoma
Merck Sharp & Dohme LLC 477
Early research (Phase 1)Looking for participantsNCT05912075
What this trial is testing

Preoperative Radiotherapy And ASTX660 in Rectum Cancer

Who this might be right for
Locally-advanced Rectal Cancer
Gustave Roussy, Cancer Campus, Grand Paris 78
Early research (Phase 1)UnknownNCT06304597
What this trial is testing

Evaluating PD-1/PD-L1 in Locally Advanced Rectal Cancer by Quantitative Fluorescence Molecular Endoscopy

Who this might be right for
Locally Advanced Rectal Carcinoma
University Medical Center Groningen 18
Testing effectiveness (Phase 2)UnknownNCT01237665
What this trial is testing

IXO (Irinotecan, Xeloda, Oxaliplatin) in Rectal Cancer

Who this might be right for
Rectal Cancer
Ottawa Hospital Research Institute 15
Testing effectiveness (Phase 2)Study completedNCT00551421
What this trial is testing

Pertuzumab and Cetuximab in Treating Patients With Previously Treated Locally Advanced or Metastatic Colorectal Cancer

Who this might be right for
Adenocarcinoma of the ColonAdenocarcinoma of the RectumRecurrent Colon Cancer+5 more
National Cancer Institute (NCI) 17
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07469306
What this trial is testing

Short-Course RT Plus CAPOX and Tislelizumab vs Long-Course CRT Plus Tislelizumab for Locally Advanced Rectal Cancer

Who this might be right for
Locally Advanced Rectal Cancer
Fujian Cancer Hospital 130
Large-scale testing (Phase 3)Looking for participantsNCT07528209
What this trial is testing

Neoadjuvant CAPOX With or Without Pucotenlimab Plus Selective Radiotherapy for Locally Advanced Rectal Cancer

Who this might be right for
Rectal CancerpMMR (Microsatellite Stable Rectal Cancer)
Sun Yat-sen University 556
Testing effectiveness (Phase 2)UnknownNCT04663763
What this trial is testing

Neoadjuvant Short-course Radiotherapy Followed by the Combination of Immunotherapy and Chemotherapy in Locally Advanced Rectal Cancer

Who this might be right for
Locally Advanced Rectal Cancer
Zhejiang Cancer Hospital 40
Testing effectiveness (Phase 2)Looking for participantsNCT06542588
What this trial is testing

Short-Course Radiotherapy Followed by Neoadjuvant Chemotherapy, HLX07and Serplulimab in LARC

Who this might be right for
Rectal Cancer
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 29
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