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Results for “Locally Advanced Renal Pelvis Carcinoma”

42 trials

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Showing 20 of 42 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT04953104
What this trial is testing

ARID1A and/or KDM6A Mutation and CXCL13 Expression

Who this might be right for
Locally Advanced Bladder Urothelial CarcinomaLocally Advanced Renal Pelvis Urothelial CarcinomaLocally Advanced Ureter Urothelial Carcinoma+29 more
M.D. Anderson Cancer Center 6
Early research (Phase 1)Looking for participantsNCT05614739
What this trial is testing

FORAGER-1: A Study of LOXO-435 (LY3866288) in Participants With Cancer With a Change in a Gene Called FGFR3

Who this might be right for
Urinary Bladder NeoplasmsNeoplasm MetastasisUreteral Neoplasms
Eli Lilly and Company 535
Early research (Phase 1)Study completedNCT02443324
What this trial is testing

Ramucirumab Plus Pembrolizumab in Participants With Gastric or GEJ Adenocarcinoma, NSCLC, Transitional Cell Carcinoma of the Urothelium, or Biliary Tract Cancer

Who this might be right for
Gastric AdenocarcinomaAdenocarcinoma of the Gastroesophageal JunctionNon-small Cell Lung Cancer+2 more
Eli Lilly and Company 175
Testing effectiveness (Phase 2)Ended earlyNCT03288545
What this trial is testing

Enfortumab Vedotin Alone or With Other Therapies for Treatment of Urothelial Cancer

Who this might be right for
Carcinoma, Transitional CellUrinary Bladder NeoplasmsUrologic Neoplasms+4 more
Astellas Pharma Global Development, Inc. 348
Testing effectiveness (Phase 2)Study completedNCT00080795
What this trial is testing

Neoadjuvant Ifosfamide, Doxorubicin, Gemcitabine, and Cisplatin in Treating Patients Who Are Undergoing Radical Cystectomy for Locally Advanced Carcinoma (Cancer) of the Urothelium

Who this might be right for
Bladder CancerTransitional Cell Cancer of the Renal Pelvis and UreterUrethral Cancer
M.D. Anderson Cancer Center 65
Large-scale testing (Phase 3)Active Not RecruitingNCT03244384
What this trial is testing

Testing MK-3475 (Pembrolizumab) After Surgery for Localized Muscle-Invasive Bladder Cancer and Locally Advanced Urothelial Cancer

Who this might be right for
Localized Renal Pelvis and Ureter Urothelial CarcinomaLocally Advanced Bladder Urothelial CarcinomaLocally Advanced Renal Pelvis and Ureter Urothelial Carcinoma+8 more
National Cancer Institute (NCI) 739
Large-scale testing (Phase 3)Active Not RecruitingNCT04637594
What this trial is testing

Trying to Find the Correct Length of Treatment With Immune Checkpoint Therapy

Who this might be right for
Locally Advanced Bladder Urothelial CarcinomaLocally Advanced Renal Pelvis Urothelial CarcinomaLocally Advanced Ureter Urothelial Carcinoma+7 more
Alliance for Clinical Trials in Oncology 3
Early research (Phase 1)Study completedNCT00003133
What this trial is testing

Combination Chemotherapy Following Surgery in Treating Patients With Advanced Bladder Cancer

Who this might be right for
Bladder CancerTransitional Cell Cancer of the Renal Pelvis and Ureter
Memorial Sloan Kettering Cancer Center 30
Testing effectiveness (Phase 2)Study completedNCT01282463
What this trial is testing

Study of Ramucirumab or Icrucumab (IMC-18F1) With Docetaxel or Docetaxel Alone as Second-Line Therapy in Participants With Bladder,Urethra, Ureter, or Renal Pelvis Carcinoma

Who this might be right for
Carcinoma of Urinary TractUrethral CarcinomaCarcinoma of Ureter+1 more
Eli Lilly and Company 148
Testing effectiveness (Phase 2)Active Not RecruitingNCT04940299
What this trial is testing

Tocilizumab, Ipilimumab, and Nivolumab for the Treatment of Advanced Melanoma, Non-Small Cell Lung Cancer, or Urothelial Carcinoma

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8Locally Advanced Bladder Carcinoma+39 more
M.D. Anderson Cancer Center 35
Testing effectiveness (Phase 2)Study completedNCT00041106
What this trial is testing

Gefitinib Plus Combination Chemotherapy in Treating Patients With Locally Advanced or Metastatic Bladder Cancer

Who this might be right for
Metastatic Transitional Cell Cancer of the Renal Pelvis and UreterRecurrent Transitional Cell Cancer of the Renal Pelvis and Ureter
National Cancer Institute (NCI) 50
Large-scale testing (Phase 3)Study completedNCT00022191
What this trial is testing

Cisplatin Plus Gemcitabine With or Without Paclitaxel in Treating Patients With Stage IV Urinary Tract Cancer

Who this might be right for
Bladder CancerTransitional Cell Cancer of the Renal Pelvis and UreterUrethral Cancer
European Organisation for Research and Treatment of Cancer - EORTC 608
Early research (Phase 1)Active Not RecruitingNCT03170960
What this trial is testing

Study of Cabozantinib Alone or in Combination With Atezolizumab to Subjects With Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Urothelial CarcinomaRenal Cell CarcinomaNon-Small Cell Lung Cancer+11 more
Exelixis 914
Testing effectiveness (Phase 2)Study completedNCT01089088
What this trial is testing

Gemcitabine Hydrochloride, Cisplatin, and Sunitinib Malate as First-Line Therapy in Treating Patients With Locally Advanced And/or Metastatic Transitional Cell Carcinoma of the Urothelium (SUCCINCT)

Who this might be right for
Bladder CancerTransitional Cell Cancer of the Renal Pelvis and UreterUrethral Cancer
Cardiff University 63
Testing effectiveness (Phase 2)Looking for participantsNCT07469683
What this trial is testing

An Open-label, Randomized Phase 2 Clinical Trial to Evaluate the Efficacy and Safety of the Combination Therapy of SLC-3010 and Axitinib Compared to Axitinib Monotherapy as a Second-line Treatment for Locally Advanced or Metastatic Clear Cell Renal Cell Carcinoma

Who this might be right for
Clear Cell Renal Cell CarcinomaNeoplasmsMalignant Neoplasms+1 more
Yonsei University 78
Large-scale testing (Phase 3)Study completedNCT02426125
What this trial is testing

Ramucirumab (LY3009806) Plus Docetaxel in Participants With Urothelial Cancer

Who this might be right for
Urothelial Carcinoma
Eli Lilly and Company 530
Early research (Phase 1)Ended earlyNCT06630247
What this trial is testing

A Dose-escalation, Dose-finding, and Expansion Study of XL495 in Participants With Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Solid CancersSolid Tumor CancerSolid Tumor Malignancy+4 more
Exelixis 9
Testing effectiveness (Phase 2)WithdrawnNCT03935347
What this trial is testing

Adoptive Cell Therapy With (LN-145) in Combination With Pembrolizumab in Treating Patients With Unresectable or Metastatic Transitional Cell Cancer Who Have Failed Cisplatin-Based Chemotherapy

Who this might be right for
Metastatic Bladder Urothelial CarcinomaMetastatic Renal Pelvis Urothelial CarcinomaMetastatic Ureter Urothelial Carcinoma+3 more
Roswell Park Cancer Institute
Testing effectiveness (Phase 2)Study completedNCT01191892
What this trial is testing

Carboplatin and Gemcitabine Hydrochloride With or Without Vandetanib as First-Line Therapy in Treating Patients With Locally Advanced or Metastatic Urinary Tract Cancer

Who this might be right for
Bladder CancerTransitional Cell Cancer of the Renal Pelvis and UreterUreter Cancer+1 more
Cardiff University 82
Testing effectiveness (Phase 2)Looking for participantsNCT07410676
What this trial is testing

EBNK-001 Allogeneic NK Cells With Low-Dose IL-15 ± Pembrolizumab in Advanced Solid Tumors

Who this might be right for
CancerSarcomaLeukaemia+12 more
Essen Biotech 83
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