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Results for “Locally Advanced Unresectable Esophageal Squamous Carcinoma”

53 trials

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Showing 20 of 53 results

Testing effectiveness (Phase 2)Not Yet RecruitingNCT07128693
What this trial is testing

A Single-center, Multicohort, Phase II Clinical Study Evaluating the Combination Therapy of Sacituzumab Tirumotecan in Patients With Unresectable, Locally Advanced, Recurrent, or Metastatic Esophageal Squamous Cell Carcinoma

Who this might be right for
Esophageal Squamous Cell Carcinoma
The First Affiliated Hospital of Zhengzhou University 60
Testing effectiveness (Phase 2)UnknownNCT04054518
What this trial is testing

Durvalumab as Maintenance Following Chemoradiation for Unresectable Esophageal Squamous Cell Carcinoma

Who this might be right for
Esophageal Squamous Cell Carcinoma
Tiago Biachi 22
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07112833
What this trial is testing

A Phase II Clinical Study of Induction Adebrelimab Combined With Chemotherapy Followed by Concurrent Chemoradiotherapy for Locally Advanced Unresectable Esophageal Squamous Cell Carcinoma (ESCC)

Who this might be right for
Locally Advanced Unresectable Esophageal Squamous Cell Carcinoma
Hebei Medical University Fourth Hospital 36
Testing effectiveness (Phase 2)Looking for participantsNCT07061704
What this trial is testing

Oncolytic Virus in Esophageal Squamous Cell Carcinoma

Who this might be right for
Esophageal Cancer
Sichuan University 40
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06452602
What this trial is testing

Induction Immunochemotherapy Followed by Concurrent Chemoradiotherapy in Patients With ESCC.

Who this might be right for
Esophageal Cancer
Tianjin Medical University Cancer Institute and Hospital 60
Large-scale testing (Phase 3)Study completedNCT03783442
What this trial is testing

Tislelizumab (BGB-A317) in Combination With Chemotherapy as First Line Treatment in Participants With Advanced Esophageal Squamous Cell Carcinoma

Who this might be right for
Esophageal Squamous Cell Carcinoma (ESCC)
BeiGene 649
Testing effectiveness (Phase 2)Looking for participantsNCT06885814
What this trial is testing

Efficacy and Safety of Adebrelimab Combined With Chemoradiotherapy in Patients With Unresectable Locally Advanced or Postoperative Recurrent Esophageal Squamous Cell Carcinoma

Who this might be right for
Esophageal Squamous Cell Carcinoma
Nanfang Hospital, Southern Medical University 30
Testing effectiveness (Phase 2)Looking for participantsNCT06780111
What this trial is testing

Substudy 06E: Umbrella Study of Combination Therapies in Esophageal Cancer (MK-3475-06E/KEYMAKER-U06)

Who this might be right for
Esophageal Squamous Cell Carcinoma
Merck Sharp & Dohme LLC 298
Testing effectiveness (Phase 2)Study completedNCT04732494
What this trial is testing

Anti-PD-1 Monoclonal Antibody Tislelizumab (BGB-A317) Combined With or Without Anti-TIGIT Monoclonal Antibody Ociperlimab (BGB-A1217) in Participants With Recurrent or Metastatic Esophageal Squamous Cell Carcinoma

Who this might be right for
Esophageal Squamous Cell Carcinoma
BeiGene 125
Large-scale testing (Phase 3)Study completedNCT03748134
What this trial is testing

Sintilimab or Placebo With Chemotherapy in Esophageal Squamous Cell Carcinoma ( ORIENT-15 )

Who this might be right for
Esophageal Squamous Cell Carcinoma
Innovent Biologics (Suzhou) Co. Ltd. 746
Large-scale testing (Phase 3)Study completedNCT04187352
What this trial is testing

CS1001 in Subjects With Esophageal Squamous Cell Carcinoma

Who this might be right for
Unresectable Locally Advanced, Recurrent or Metastatic Esophageal Squamous Cell Carcinoma
CStone Pharmaceuticals 540
Testing effectiveness (Phase 2)Looking for participantsNCT06675201
What this trial is testing

Neoantigen Vaccines in Esophageal Squamous Cell Carcinoma

Who this might be right for
Esophageal Squamous Cell Carcinoma (ESCC)Neoantigen-loaded Dendritic Cell VaccineImmune Checkpoint Inhibitors (ICIs)
Sichuan University 165
Large-scale testing (Phase 3)Looking for participantsNCT04415853
What this trial is testing

Study of Larotinib in Unresectable Advanced or Recurrent Esophageal Cancer

Who this might be right for
Esophageal Cancer
Sunshine Lake Pharma Co., Ltd. 416
Large-scale testing (Phase 3)Active Not RecruitingNCT04550260
What this trial is testing

Study of Durvalumab Versus Placebo in Combination With Definitive Chemoradiation Therapy in Patient With ESCC

Who this might be right for
Esophageal Squamous Cell Carcinoma
AstraZeneca 640
Testing effectiveness (Phase 2)Looking for participantsNCT06709417
What this trial is testing

A Phase II Clinical Study of Sintilimab Combined with Chemotherapy Followed by Concurrent Chemoradiotherapy for Locally Advanced Unresectable Esophageal Squamous Cell Carcinoma (ESCC) (NICE-CS)

Who this might be right for
Esophageal Squamous Cell Carcinoma (ESCC)
Shanghai Chest Hospital 52
Testing effectiveness (Phase 2)Looking for participantsNCT06265285
What this trial is testing

Comparison of In-Home Versus In-Clinic Administration of Subcutaneous Nivolumab Through Cancer CARE (Connected Access and Remote Expertise) Beyond Walls (CCBW) Program

Who this might be right for
Advanced Esophageal Squamous Cell CarcinomaAdvanced Renal Cell CarcinomaClinical Stage II Esophageal Squamous Cell Carcinoma AJCC v8+28 more
Mayo Clinic 50
Testing effectiveness (Phase 2)Active Not RecruitingNCT05945823
What this trial is testing

Phase 2 Futibatinib in Combination With PD-1 Antibody Based Standard of Care in Solid Tumors

Who this might be right for
Locally Advanced Unresectable or Metastatic Solid Tumors Including Esophageal CancerEsophageal AdenocarcinomaEsophageal Squamous Cell Cancer+2 more
Taiho Oncology, Inc. 53
Very early researchEnrolling By InvitationNCT07371247
What this trial is testing

Based on ctDNA-MRD Guided Adjuvant Treatment Escalation After Definitive Chemoradiotherapy for Unresectable Locally Advanced Esophageal Squamous Cell Carcinoma: a Study on Safety and Efficacy

Who this might be right for
Esophageal CancerMRDctDNA
The First Affiliated Hospital with Nanjing Medical University 65
Not applicableEnrolling By InvitationNCT06715501
What this trial is testing

Efficacy and Safety of Cadonilimab and Chemoradiotherapy in Unresectable Locally Advanced Esophageal Squamous Cell Carcinoma

Who this might be right for
Locally Advanced Esophageal Squamous Cell CarcinomaII-IIIB Stages
First Affiliated Hospital of Ningbo University 20
Testing effectiveness (Phase 2)Study completedNCT00021047
What this trial is testing

Epirubicin, Carboplatin, and Capecitabine in Treating Patients With Unresectable Locally Advanced, Metastatic, or Recurrent Solid Tumor

Who this might be right for
Esophageal CancerExtrahepatic Bile Duct CancerGastric Cancer+3 more
National Institutes of Health Clinical Center (CC)
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