Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Locally Advanced or Metastatic CRC”

160 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 160 results

Testing effectiveness (Phase 2)Ended earlyNCT01133990
What this trial is testing

FOLFIRI Alone Versus FOLFIRI Plus Bevacizumab Versus FOLFIRI Plus E7820 as Second-Line Therapy in Patients With Locally Advanced or Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer
Eisai Inc. 5
Early research (Phase 1)Study completedNCT00648102
What this trial is testing

Phase I Study of CDX-1307, hCG-B Vaccine, for Patients With Incurable, Locally Advanced or Metastatic Breast, Colorectal, Pancreatic, Bladder or Ovarian Cancer

Who this might be right for
Breast CancerColorectal CancerPancreatic Cancer+2 more
Celldex Therapeutics 36
Testing effectiveness (Phase 2)Ended earlyNCT00006001
What this trial is testing

SU5416 in Treating Patients With Metastatic or Locally Recurrent Colorectal Cancer

Who this might be right for
Colorectal Cancer
National Cancer Institute (NCI) 37
Not applicableStudy completedNCT02106858
What this trial is testing

Stivarga Regulatory Post-Marketing Surveillance Study in Korea

Who this might be right for
Colorectal Neoplasms
Bayer 316
Testing effectiveness (Phase 2)Active Not RecruitingNCT04117945
What this trial is testing

Regorafenib, With Cetuximab or Panitumumab, for the Treatment of Unresectable, Locally Advanced, or Metastatic Colorectal Cancer

Who this might be right for
BRAF V600E NegativeKRAS Gene Mutation NegativeLocally Advanced Unresectable Colorectal Adenocarcinoma+10 more
Academic and Community Cancer Research United 22
Testing effectiveness (Phase 2)Study completedNCT04666688
What this trial is testing

LYT-200 Alone and in Combination With Chemotherapy or Tislelizumab in Patients With Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Metastatic CancerSolid TumorPancreatic Cancer+3 more
PureTech 44
Early research (Phase 1)Study completedNCT00026364
What this trial is testing

ZD 1839 Plus Combination Chemotherapy in Treating Patients With Locally Advanced, Locally Recurrent, or Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer
National Cancer Institute (NCI) 22
Testing effectiveness (Phase 2)Study completedNCT00551421
What this trial is testing

Pertuzumab and Cetuximab in Treating Patients With Previously Treated Locally Advanced or Metastatic Colorectal Cancer

Who this might be right for
Adenocarcinoma of the ColonAdenocarcinoma of the RectumRecurrent Colon Cancer+5 more
National Cancer Institute (NCI) 17
Testing effectiveness (Phase 2)Study completedNCT01040000
What this trial is testing

QUILT-3.019: Phase 2 Study of NPC-1C Chimeric Monoclonal Antibody to Treat Pancreatic and Colorectal Cancer

Who this might be right for
Metastatic Pancreatic CancerMetastatic Colorectal Cancer
Precision Biologics, Inc 94
Testing effectiveness (Phase 2)Ended earlyNCT04844073
What this trial is testing

TAK-186 (Also Known as MVC-101) in Adults With Advanced or Metastatic Cancer

Who this might be right for
Squamous Cell Cancer of Head and Neck (SCCHN)Non-small Cell Lung Cancer (NSCLC)Colorectal Cancer
Takeda 95
Testing effectiveness (Phase 2)Looking for participantsNCT07410494
What this trial is testing

Biomarker-Guided Allogeneic Single-Target or Dual-Target CAR-NK Cell Therapy for Advanced Solid Tumors

Who this might be right for
CancerBreast CancerNon-Small Cell Lung Cancer (NSCLC)+10 more
Essen Biotech 85
Early research (Phase 1)Looking for participantsNCT06374173
What this trial is testing

Evaluate TGI-6 in Subjects With Locally Advanced/Metastatic Solid Tumors

Who this might be right for
Advanced or Metastatic Solid Tumors
Hefei TG ImmunoPharma Co., Ltd. 123
Early research (Phase 1)Study completedNCT00873756
What this trial is testing

Dulanermin Administered in Combination With the FOLFOX Regimen and Bevacizumab in Patients With Previously Untreated, Locally Advanced, Recurrent, or Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
Genentech, Inc. 23
Testing effectiveness (Phase 2)UnknownNCT06384235
What this trial is testing

Phase II Clinical Study of LTC004 in Patients With mCRC

Who this might be right for
Locally Advanced or Metastatic CRC
Letolab 30
Testing effectiveness (Phase 2)Ended earlyNCT00681876
What this trial is testing

Phase II Study of Avastin + Erbitux + Irinotecan as 2nd Line Treatment of Colorectal Cancer

Who this might be right for
Colorectal Cancer
Hellenic Oncology Research Group 16
Testing effectiveness (Phase 2)Study completedNCT05316818
What this trial is testing

Triplet (FOLFOXIRI) vs. Doublet (FOLFOX or FOLFIRI) Regimen as a 1st Line Treatment in Metastatic Colorectal Carcinoma

Who this might be right for
Metastatic Colorectal Cancer
Kasr El Aini Hospital 64
Early research (Phase 1)Not Yet RecruitingNCT07587827
What this trial is testing

Study Evaluating the Safety Feasibility and Efficacy of ODI-2001 Vaccine, a Personnalized Immunotherapy in Patients With Metastatic or Locally Advanced Colon Cancer or Pancreatic Cancer

Who this might be right for
Metastatic Colorectal Cancer (CRC)Locally Advanced Colorectal CancerMetastatic Pancreatic Cancer+1 more
Centre Georges Francois Leclerc 77
Testing effectiveness (Phase 2)Study completedNCT01802320
What this trial is testing

Akt Inhibitor MK2206 in Treating Patients With Previously Treated Colon or Rectal Cancer That is Metastatic or Locally Advanced and Cannot Be Removed by Surgery

Who this might be right for
Colon Mucinous AdenocarcinomaColon Signet Ring Cell AdenocarcinomaRectal Mucinous Adenocarcinoma+13 more
National Cancer Institute (NCI) 18
Early research (Phase 1)Looking for participantsNCT05262491
What this trial is testing

BL-B01D1 in Patients With Locally Advanced or Metastatic Gastrointestinal Tumor and Other Solid Tumor

Who this might be right for
Gastrointestinal Tumor
Sichuan Baili Pharmaceutical Co., Ltd. 96
Testing effectiveness (Phase 2)Ended earlyNCT05091528
What this trial is testing

A Safety and Activity Study of SBT6050 in Combination With Other HER2-directed Therapies for HER2-positive Cancers

Who this might be right for
HER2-positive Breast CancerHER2-positive Gastric CancerHER2-positive Colorectal Cancer+1 more
Silverback Therapeutics 2
Next Page