Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Locally Advanced or Metastatic CRC”

147 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 147 results

Testing effectiveness (Phase 2)Looking for participantsNCT07244705
What this trial is testing

ABT-301 Plus Tislelizumab With Bevacizumab in pMMR/Non-MSI-H Locally Advanced or mCRC

Who this might be right for
Colorectal Cancer (Diagnosis)Colorectal Cancer MetastaticColorectal Cancer (CRC)+1 more
Anbogen Therapeutics, Inc. 66
Testing effectiveness (Phase 2)Ended earlyNCT00959946
What this trial is testing

Study Of Bosutinib With Capecitabine In Solid Tumors And Locally Advanced Or Metastatic Breast Cancer

Who this might be right for
Advanced Breast Cancer (Parts 1 and 2)Advanced Pancreatic Cancer (Part 1)Advanced Colorectal Cancer (Part 1)+2 more
Pfizer 32
Very early researchLooking for participantsNCT07050394
What this trial is testing

A Dose-Expansion Trial of Intravenous HNF4α srRNA for Unresectable or Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer MetastaticColorectal Cancer RecurrentColorectal Cancer Stage IV
Shanghai Changzheng Hospital 20
Testing effectiveness (Phase 2)Looking for participantsNCT06682793
What this trial is testing

Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated CAR T, in Participants With Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression

Who this might be right for
Solid Tumor, AdultColorectal CancerNon-Small Cell Lung+14 more
A2 Biotherapeutics Inc. 240
Testing effectiveness (Phase 2)Study completedNCT02292758
What this trial is testing

Irinotecan and Cetuximab With or Without Bevacizumab in Treating Patients With RAS Wild-Type Locally Advanced or Metastatic Colorectal Cancer That Cannot Be Removed by Surgery

Who this might be right for
Colorectal AdenocarcinomaRAS Wild TypeStage IV Colorectal Cancer AJCC v7+2 more
Academic and Community Cancer Research United 36
Testing effectiveness (Phase 2)Study completedNCT00026299
What this trial is testing

Oxaliplatin With or Without Gefitinib in Treating Patients With Metastatic or Locally Recurrent Colorectal Cancer

Who this might be right for
Colorectal Cancer
University of Chicago 14
Large-scale testing (Phase 3)Not Yet RecruitingNCT07509398
What this trial is testing

FMT Combined With Standard First-Line Therapy in Initially Unresectable Colorectal Cancer

Who this might be right for
Unresectable Colorectal CancerColorectal Cancer (Locally Advanced or Metastatic)
Shanghai 10th People's Hospital 220
Large-scale testing (Phase 3)Study completedNCT00469443
What this trial is testing

Randomized Phase III Study of Folfiri+Avastin Versus Xeliri+Avastin as 1st Line Treatment of CRC

Who this might be right for
Colorectal Cancer
Hellenic Oncology Research Group 330
Early research (Phase 1)Active Not RecruitingNCT03821935
What this trial is testing

Study to Determine the Safety, Tolerability, Pharmacokinetics and Recommended Phase 2 Dose (RP2D) of Livmoniplimab (ABBV-151) as a Single Agent and in Combination With Budigalimab (ABBV-181) in Participants With Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Advanced Solid Tumors Cancer
AbbVie 364
Testing effectiveness (Phase 2)Looking for participantsNCT07410676
What this trial is testing

EBNK-001 Allogeneic NK Cells With Low-Dose IL-15 ± Pembrolizumab in Advanced Solid Tumors

Who this might be right for
CancerSarcomaLeukaemia+12 more
Essen Biotech 83
Testing effectiveness (Phase 2)Ended earlyNCT00681876
What this trial is testing

Phase II Study of Avastin + Erbitux + Irinotecan as 2nd Line Treatment of Colorectal Cancer

Who this might be right for
Colorectal Cancer
Hellenic Oncology Research Group 16
Not applicableActive Not RecruitingNCT05487248
What this trial is testing

On-treatment ctDNA Changes in Chemo-refractory Colorectal Cancer Patients

Who this might be right for
Unresectable Locally Advanced Colorectal CancerMetastatic Colorectal CancerCandidate for Third-line or Subsequent Lines of Therapy
Jules Bordet Institute 103
Early research (Phase 1)UnknownNCT03260179
What this trial is testing

Study to Evaluate the Safety, Preliminary Efficacy and Pharmacokinetics of 3810

Who this might be right for
Advanced Solid TumorAdvanced/Metastatic Colorectal Cancer
Haihe Biopharma Co., Ltd. 60
Early research (Phase 1)Study completedNCT01846650
What this trial is testing

A Bioequivalence Study of Capecitabine Tablets

Who this might be right for
Metastatic Breast Cancer or Metastatic Colorectal Cancer
Chia Tai Tianqing Pharmaceutical Group Co., Ltd. 36
Large-scale testing (Phase 3)Looking for participantsNCT05078047
What this trial is testing

Study Comparing the Standard Administration of IO Versus the Same IO Administered Each 3 Months in Patients in Response After 6 Months of Standard IO

Who this might be right for
Lung Cancer MetastaticRenal Cell CarcinomaHead and Neck Cancer+12 more
UNICANCER 646
Testing effectiveness (Phase 2)Looking for participantsNCT06792435
What this trial is testing

XNW27011 Study of Advanced Solid Tumor Subjects Who Failed Standard Therapies.

Who this might be right for
Pancreatic Adenocarcinoma MetastaticLung Cancer (NSCLC)Ovarian Cancer+4 more
Evopoint Biosciences Inc. 240
Testing effectiveness (Phase 2)Looking for participantsNCT05705492
What this trial is testing

Olanzapine for the Management of Cancer Associated Appetite Loss in Patients With Advanced Esophagogastric, Hepatopancreaticobiliary, Colorectal or Lung Cancer

Who this might be right for
Advanced Malignant Solid NeoplasmAdvanced Biliary Tract CarcinomaAdvanced Esophageal Carcinoma+7 more
OHSU Knight Cancer Institute 66
Testing effectiveness (Phase 2)Ended earlyNCT01993472
What this trial is testing

Study of Andrographolides With or Without Capecitabine to Treat Colorectal Cancer

Who this might be right for
Colorectal Neoplasms
Gu Yanhong 308
Testing effectiveness (Phase 2)Active Not RecruitingNCT02568267
What this trial is testing

Basket Study of Entrectinib (RXDX-101) for the Treatment of Patients With Solid Tumors Harboring NTRK 1/2/3 (Trk A/B/C), ROS1, or ALK Gene Rearrangements (Fusions)

Who this might be right for
Breast CancerCholangiocarcinomaColorectal Cancer+13 more
Hoffmann-La Roche 534
Large-scale testing (Phase 3)Study completedNCT00975897
What this trial is testing

Study of Tumor Tissue Testing in Selecting Treatment for Patients With Metastatic or Locally Advanced Colorectal Cancer

Who this might be right for
Colorectal Cancer
Medical Research Council 3,240
Load More Results