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Results for “Locally Advanced or Metastatic CRC”

154 trials

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Showing 20 of 154 results

Testing effectiveness (Phase 2)Ended earlyNCT00959946
What this trial is testing

Study Of Bosutinib With Capecitabine In Solid Tumors And Locally Advanced Or Metastatic Breast Cancer

Who this might be right for
Advanced Breast Cancer (Parts 1 and 2)Advanced Pancreatic Cancer (Part 1)Advanced Colorectal Cancer (Part 1)+2 more
Pfizer 32
Testing effectiveness (Phase 2)Study completedNCT01802320
What this trial is testing

Akt Inhibitor MK2206 in Treating Patients With Previously Treated Colon or Rectal Cancer That is Metastatic or Locally Advanced and Cannot Be Removed by Surgery

Who this might be right for
Colon Mucinous AdenocarcinomaColon Signet Ring Cell AdenocarcinomaRectal Mucinous Adenocarcinoma+13 more
National Cancer Institute (NCI) 18
Testing effectiveness (Phase 2)Looking for participantsNCT07410494
What this trial is testing

Biomarker-Guided Allogeneic Single-Target or Dual-Target CAR-NK Cell Therapy for Advanced Solid Tumors

Who this might be right for
CancerBreast CancerNon-Small Cell Lung Cancer (NSCLC)+10 more
Essen Biotech 85
Testing effectiveness (Phase 2)Ended earlyNCT00006001
What this trial is testing

SU5416 in Treating Patients With Metastatic or Locally Recurrent Colorectal Cancer

Who this might be right for
Colorectal Cancer
National Cancer Institute (NCI) 37
Early research (Phase 1)Active Not RecruitingNCT05907304
What this trial is testing

Assess Naporafenib (ERAS-254) Administered With Trametinib in Patients With RAS Q61X Mutations

Who this might be right for
Advanced or Metastatic Solid Tumors
Erasca, Inc. 86
Early research (Phase 1)Study completedNCT04468607
What this trial is testing

BLYG8824A in Participants With Locally Advanced or Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer
Genentech, Inc. 46
Testing effectiveness (Phase 2)Study completedNCT04744831
What this trial is testing

Trastuzumab Deruxtecan in Participants With HER2-overexpressing Advanced or Metastatic Colorectal Cancer

Who this might be right for
Advanced Colorectal Cancer
Daiichi Sankyo 122
Testing effectiveness (Phase 2)Study completedNCT00094809
What this trial is testing

Chemotherapy Administered Every 2 Weeks With or Without Pegfilgrastim in Subjects With Advanced or Metastatic Colon Cancer

Who this might be right for
Colon CancerColorectal CancerRectal Cancer
Amgen 252
Testing effectiveness (Phase 2)Active Not RecruitingNCT04579380
What this trial is testing

Basket Study of Tucatinib and Trastuzumab in Solid Tumors With HER2 Alterations

Who this might be right for
Uterine NeoplasmsUterine Cervical NeoplasmsBiliary Tract Neoplasms+3 more
Seagen, a wholly owned subsidiary of Pfizer 217
Early research (Phase 1)Study completedNCT03289962
What this trial is testing

Autogene Cevumeran (RO7198457) as a Single Agent and in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Tumors

Who this might be right for
MelanomaNon-Small Cell Lung CancerBladder Cancer+5 more
Genentech, Inc. 273
Early research (Phase 1)Active Not RecruitingNCT05867303
What this trial is testing

A RC198 Study in Subjects With Locally Advanced Unresectable or Metastatic Solid Tumors

Who this might be right for
MelanomaUrothelial CarcinomaRenal Cell Carcinoma+3 more
RemeGen Co., Ltd. 48
Not applicableNot Yet RecruitingNCT06470178
What this trial is testing

A Real-World Study of Neoadjuvant/Conversion Therapy for Colorectal Cancer With Chemotherapy And Anti-Angiogenic Targeted Agents

Who this might be right for
Colorectal Cancer
Wuhan University 70
Testing effectiveness (Phase 2)Study completedNCT00030524
What this trial is testing

ZD 1839 in Treating Patients With Locally Advanced or Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer
The University of Texas Health Science Center at San Antonio
Testing effectiveness (Phase 2)Looking for participantsNCT06362369
What this trial is testing

Oral 7HP349 (Alintegimod) in Combination With Ipilimumab Followed by Nivolumab Monotherapy

Who this might be right for
Advanced CancerAdvanced Solid TumorMelanoma+15 more
7 Hills Pharma, LLC 126
Testing effectiveness (Phase 2)Study completedNCT00026299
What this trial is testing

Oxaliplatin With or Without Gefitinib in Treating Patients With Metastatic or Locally Recurrent Colorectal Cancer

Who this might be right for
Colorectal Cancer
University of Chicago 14
Testing effectiveness (Phase 2)Study completedNCT03799731
What this trial is testing

Study for Evaluation of Murlentamab (GM102) Anti-tumoral Activity in Colorectal Cancers

Who this might be right for
Colorectal Cancer
GamaMabs Pharma 65
Early research (Phase 1)Looking for participantsNCT05382559
What this trial is testing

ASP3082 in Adults With Advanced Solid Tumors

Who this might be right for
Solid Tumor
Astellas Pharma Inc 681
Early research (Phase 1)Study completedNCT00648102
What this trial is testing

Phase I Study of CDX-1307, hCG-B Vaccine, for Patients With Incurable, Locally Advanced or Metastatic Breast, Colorectal, Pancreatic, Bladder or Ovarian Cancer

Who this might be right for
Breast CancerColorectal CancerPancreatic Cancer+2 more
Celldex Therapeutics 36
Large-scale testing (Phase 3)Looking for participantsNCT06997497
What this trial is testing

A Clinical Study of Calderasib (MK-1084) With Targeted Therapy and Chemotherapy in People With Colorectal Cancer (MK-1084-012/KANDLELIT-012)

Who this might be right for
Colon AdenocarcinomaRectal Adenocarcinoma
Merck Sharp & Dohme LLC 477
Early research (Phase 1)Study completedNCT02457793
What this trial is testing

The Safety, Tolerability, and Effects of Cobimetinib and GDC-0994 in Patients With Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Non-Small Cell Lung Cancer, Metastatic Colorectal Cancer, Metastatic Non Small Cell Lung Cancer, Metastatic Cancers, Melanoma
Genentech, Inc. 24
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