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Results for “Locally Advanced or Metastatic Malignant Solid Tumors”

66 trials

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Showing 20 of 66 results

Early research (Phase 1)WithdrawnNCT06626256
What this trial is testing

STIL101 for Injection for the Treatment of Locally Advanced, Metastatic or Unresectable Pancreatic Cancer, Colorectal Cancer, Renal Cell Cancer, Cervical Cancer and Melanoma

Who this might be right for
Locally Advanced Cervical CarcinomaLocally Advanced Colorectal CarcinomaLocally Advanced Malignant Solid Neoplasm+24 more
City of Hope Medical Center
Early research (Phase 1)Active Not RecruitingNCT05311397
What this trial is testing

A166 in Patients With Advanced Solid Malignant Tumors

Who this might be right for
Breast Cancer
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. 120
Testing effectiveness (Phase 2)Ended earlyNCT04260802
What this trial is testing

Evaluate the Safety and Pharmacokinetics of OC-001 in Patients With Locally Advanced or Metastatic Cancers

Who this might be right for
CancerNeoplasmsMetastatic Cancer+16 more
Ocellaris Pharma, Inc. 73
Testing effectiveness (Phase 2)Active Not RecruitingNCT04940299
What this trial is testing

Tocilizumab, Ipilimumab, and Nivolumab for the Treatment of Advanced Melanoma, Non-Small Cell Lung Cancer, or Urothelial Carcinoma

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8Locally Advanced Bladder Carcinoma+39 more
M.D. Anderson Cancer Center 35
Testing effectiveness (Phase 2)Looking for participantsNCT07105215
What this trial is testing

A I/II Phase Clinical Study to Evaluate the Safety and Efficacy of RC278 in the Treatment of Solid Tumors

Who this might be right for
Solid Tumors
RemeGen Co., Ltd. 312
Early research (Phase 1)Looking for participantsNCT05098210
What this trial is testing

Personalized Neo-Antigen Peptide Vaccine for the Treatment of Stage IIIC-IV Melanoma, Hormone Receptor Positive HER2 Negative Metastatic Refractory Breast Cancer or Stage III-IV Non-Small Cell Lung Cancer

Who this might be right for
Anatomic Stage IV Breast Cancer AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8Locally Advanced Cutaneous Melanoma+22 more
Fred Hutchinson Cancer Center 25
Early research (Phase 1)Active Not RecruitingNCT02321501
What this trial is testing

Ceritinib and Everolimus in Treating Patients With Locally Advanced or Metastatic Solid Tumors or Stage IIIB-IV Non-small Cell Lung Cancer

Who this might be right for
ALK PositiveLocally Advanced Malignant Solid NeoplasmMetastatic Malignant Solid Neoplasm+3 more
M.D. Anderson Cancer Center 37
Testing effectiveness (Phase 2)Looking for participantsNCT07287995
What this trial is testing

ASP2998 Given by Itself and Given With Standard Therapies in People With Solid Tumors

Who this might be right for
Locally Advanced or Metastatic Malignant Solid Tumors
Astellas Pharma Global Development, Inc. 428
Testing effectiveness (Phase 2)Active Not RecruitingNCT03583255
What this trial is testing

Physical Activity With or Without Dexamethasone in Reducing Cancer-Related Fatigue in Patients With Locally Advanced, Metastatic, or Recurrent Cancer

Who this might be right for
Advanced Malignant Solid NeoplasmHematopoietic and Lymphoid System NeoplasmLocally Advanced Malignant Solid Neoplasm+2 more
M.D. Anderson Cancer Center 99
Early research (Phase 1)Study completedNCT00721266
What this trial is testing

A Dose-Escalation Study of RO5083945 in Patients With Metastatic and/or Locally Advanced Malignant Epidermal Growth Factor Receptor (EGFR)+ Solid Tumors.

Who this might be right for
Neoplasms
Hoffmann-La Roche 102
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07282873
What this trial is testing

Study of TYK-01054 Capsules in Patients With Advanced Solid Tumors

Who this might be right for
Solid Tumor MalignanciesMalignant Mesothelioma (MM)
TYK Medicines, Inc 219
Early research (Phase 1)Looking for participantsNCT04511039
What this trial is testing

Trifluridine/Tipiracil and Talazoparib for the Treatment of Patients With Locally Advanced or Metastatic Colorectal or Gastroesophageal Cancer

Who this might be right for
Advanced Malignant Solid NeoplasmClinical Stage III Gastroesophageal Junction AdenocarcinomaClinical Stage IV Gastroesophageal Junction Adenocarcinoma+26 more
Roswell Park Cancer Institute 45
Early research (Phase 1)Active Not RecruitingNCT03845166
What this trial is testing

XL092 as Single-Agent and Combination Therapy in Subjects With Solid Tumors

Who this might be right for
Neoplasm MalignantRenal Cell CarcinomaHormone Receptor Positive Breast Carcinoma+2 more
Exelixis 325
Early research (Phase 1)Study completedNCT03238027
What this trial is testing

Investigate Axatilimab Alone or in Combination With Durvalumab in Patients With Solid Tumors

Who this might be right for
Solid TumorMetastatic TumorLocally Advanced Malignant Neoplasm+1 more
Syndax Pharmaceuticals 45
Testing effectiveness (Phase 2)Looking for participantsNCT06016062
What this trial is testing

RC148 As a Single Agent and Combination Therapy in Patients with Locally Advanced Unresectable or Metastatic Malignant Solid Tumors

Who this might be right for
Solid Tumor
RemeGen Co., Ltd. 221
Early research (Phase 1)UnknownNCT05554666
What this trial is testing

ASKG315 in Patients With Advanced Solid Tumors.

Who this might be right for
Advanced Solid Tumors
AskGene Pharma, Inc. 56
Testing effectiveness (Phase 2)Looking for participantsNCT06038396
What this trial is testing

RC118 Plus Toripalimab / RC148 in Patients with Locally Advanced Unresectable or Metastatic Solid Tumors

Who this might be right for
Advanced Solid Tumor
RemeGen Co., Ltd. 48
Testing effectiveness (Phase 2)Ended earlyNCT05169437
What this trial is testing

Niraparib in the Treatment of Patients With Advanced PALB2 Mutated Tumors

Who this might be right for
Solid TumorBreast TumorColon Tumor, Malignant+9 more
Tempus AI 22
Testing effectiveness (Phase 2)Looking for participantsNCT05564377
What this trial is testing

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

Who this might be right for
Advanced Malignant Solid NeoplasmAnatomic Stage III Breast Cancer AJCC v8Anatomic Stage IV Breast Cancer AJCC v8+12 more
National Cancer Institute (NCI) 2,900
Testing effectiveness (Phase 2)Study completedNCT04121442
What this trial is testing

Isunakinra Alone and in Combination With a PD-1/PD-L1 Inhibitor in Patients With Solid Tumors

Who this might be right for
Solid Tumor, Adult
Buzzard Pharmaceuticals 15
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