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Results for “Locally Advanced or Metastatic Urinary Tumors”

105 trials

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Showing 20 of 105 results

Early research (Phase 1)Study completedNCT01976741
What this trial is testing

Dose Escalation Pan-FGFR (Fibroblast Growth Factor Receptor) Inhibitor (Rogaratinib)

Who this might be right for
Neoplasms
Bayer 168
Testing effectiveness (Phase 2)Active Not RecruitingNCT04953104
What this trial is testing

ARID1A and/or KDM6A Mutation and CXCL13 Expression

Who this might be right for
Locally Advanced Bladder Urothelial CarcinomaLocally Advanced Renal Pelvis Urothelial CarcinomaLocally Advanced Ureter Urothelial Carcinoma+29 more
M.D. Anderson Cancer Center 6
Early research (Phase 1)Looking for participantsNCT05614739
What this trial is testing

FORAGER-1: A Study of LOXO-435 (LY3866288) in Participants With Cancer With a Change in a Gene Called FGFR3

Who this might be right for
Urinary Bladder NeoplasmsNeoplasm MetastasisUreteral Neoplasms
Eli Lilly and Company 535
Testing effectiveness (Phase 2)Ended earlyNCT04424641
What this trial is testing

A Study on the Safety of GEN1044 (DuoBody®-CD3x5T4) in Patients With Malignant Solid Tumors

Who this might be right for
Locally Advanced or Metastatic Solid Tumor(s)Prostate CancerEsophageal Cancer+5 more
Genmab 48
Early research (Phase 1)Enrolling By InvitationNCT07218003
What this trial is testing

A Phase 1/1b of RNDO-564 Single Agent or in Combination With Pembrolizumab in Bladder Cancer and Other Solid Tumors Associated With Nectin-4

Who this might be right for
Non Small Cell Lung CancerCervical CancerHead and Neck Squamous Cell Cancer+7 more
Rondo Therapeutics 149
Early research (Phase 1)Study completedNCT03289962
What this trial is testing

Autogene Cevumeran (RO7198457) as a Single Agent and in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Tumors

Who this might be right for
MelanomaNon-Small Cell Lung CancerBladder Cancer+5 more
Genentech, Inc. 273
Early research (Phase 1)Looking for participantsNCT07492628
What this trial is testing

Dual-Target Nectin-4/HER2 CAR-NK Cells in Advanced Urothelial Carcinoma

Who this might be right for
Bladder CancerUrothelial CarcinomaMetastatic Urothelial Carcinoma+2 more
Beijing Biotech 42
Testing effectiveness (Phase 2)Looking for participantsNCT06031584
What this trial is testing

BL-M07D1 in Patients With a Variety of Solid Tumors Including Locally Advanced or Metastatic HER2-positive/Low-expressing Urinary and Gastrointestinal Tumors

Who this might be right for
Her2-positive/Low-expression Urinary and Digestive Tract Tumors
Sichuan Baili Pharmaceutical Co., Ltd. 42
Testing effectiveness (Phase 2)WithdrawnNCT06424717
What this trial is testing

Study of Avelumab and Tuvusertib in Participants With Advanced Urothelial Cancer That Has Progressed on Prior Anti-PD-(L)1 Therapy (JAVELIN DDRiver Bladder)

Who this might be right for
Urothelial Carcinoma
EMD Serono Research & Development Institute, Inc.
Large-scale testing (Phase 3)UnknownNCT00949455
What this trial is testing

A Double Blind Randomised Study of Lapatinib and Placebo in Metastatic TCC of the Urothelium

Who this might be right for
Bladder Cancer
Queen Mary University of London 204
Testing effectiveness (Phase 2)Study completedNCT03785925
What this trial is testing

A Single-Arm Study of Bempegaldesleukin (NKTR-214) Plus Nivolumab in Cisplatin Ineligible Patients Who Have Locally Advanced or Metastatic Urothelial Cancer

Who this might be right for
Urinary Bladder NeoplasmNeoplasm Metastasis
Nektar Therapeutics 192
Testing effectiveness (Phase 2)Study completedNCT02001623
What this trial is testing

Tisotumab Vedotin (HuMax®-TF-ADC) Safety Study in Patients With Solid Tumors

Who this might be right for
Ovary CancerCervix CancerEndometrium Cancer+5 more
Seagen Inc. 195
Large-scale testing (Phase 3)Looking for participantsNCT07129993
What this trial is testing

Study of Datopotamab Deruxtecan Plus Carboplatin or Cisplatin Versus Gemcitabine Plus Carboplatin or Cisplatin in Participants With Locally Advanced or Metastatic Urothelial Carcinoma

Who this might be right for
Urothelial CancerBladder Cancer
Daiichi Sankyo 630
Testing effectiveness (Phase 2)Ended earlyNCT00089128
What this trial is testing

Gemcitabine and Irinotecan in Treating Patients With Locally Advanced or Metastatic Bladder Cancer

Who this might be right for
Bladder Cancer
Medical University of South Carolina 16
Testing effectiveness (Phase 2)Study completedNCT03628716
What this trial is testing

CV301 Combined With PD-1/L1 Blockade in Patients With Locally Advanced or Metastatic Urothelial Bladder Cancer

Who this might be right for
Bladder Cancer
Bavarian Nordic 43
Not applicableStudy completedNCT00253708
What this trial is testing

Massage Therapy in Treating the Symptoms of Patients With Locally Advanced or Metastatic Cancer

Who this might be right for
Cancer
Beth Israel Deaconess Medical Center 39
Early research (Phase 1)Study completedNCT00648102
What this trial is testing

Phase I Study of CDX-1307, hCG-B Vaccine, for Patients With Incurable, Locally Advanced or Metastatic Breast, Colorectal, Pancreatic, Bladder or Ovarian Cancer

Who this might be right for
Breast CancerColorectal CancerPancreatic Cancer+2 more
Celldex Therapeutics 36
Early research (Phase 1)Study completedNCT02443324
What this trial is testing

Ramucirumab Plus Pembrolizumab in Participants With Gastric or GEJ Adenocarcinoma, NSCLC, Transitional Cell Carcinoma of the Urothelium, or Biliary Tract Cancer

Who this might be right for
Gastric AdenocarcinomaAdenocarcinoma of the Gastroesophageal JunctionNon-small Cell Lung Cancer+2 more
Eli Lilly and Company 175
Testing effectiveness (Phase 2)Ended earlyNCT03288545
What this trial is testing

Enfortumab Vedotin Alone or With Other Therapies for Treatment of Urothelial Cancer

Who this might be right for
Carcinoma, Transitional CellUrinary Bladder NeoplasmsUrologic Neoplasms+4 more
Astellas Pharma Global Development, Inc. 348
Large-scale testing (Phase 3)Study completedNCT02302807
What this trial is testing

Atezolizumab Compared With Chemotherapy in Participants With Locally Advanced or Metastatic Urothelial Bladder Cancer [IMvigor211]

Who this might be right for
Bladder Cancer
Hoffmann-La Roche 931
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