Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Loss of Heterozygosity”

18 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 18 of 18 results

Not applicableUnknownNCT04651933
What this trial is testing

A Training Set for the HRD Model in EOC

Who this might be right for
Epithelial Ovarian CancerBRCA MutationLoss of Heterozygosity+3 more
Lei Li 200
Not applicableStudy completedNCT03621007
What this trial is testing

An Observational,Prospective Natural History Study of Early-Onset Extreme Obesity Due to Bi-Allelic Loss-of-Function Mutations in the POMC, PCSK1 or LEPR Genes

Who this might be right for
POMC Deficiency ObesityPCSK1 Deficiency ObesityLEPR Deficiency Obesity
Rhythm Pharmaceuticals, Inc. 8
Not applicableUnknownNCT02436746
What this trial is testing

The Cognitive Variability in NF1 and TSC Monozygotic Twins

Who this might be right for
Neurofibromatosis Type ITuberous Sclerosis Complex
Erasmus Medical Center 116
Large-scale testing (Phase 3)Study completedNCT00402779
What this trial is testing

Erlotinib Prevention of Oral Cancer (EPOC)

Who this might be right for
Oral Cancer
M.D. Anderson Cancer Center 303
Testing effectiveness (Phase 2)Study completedNCT01891344
What this trial is testing

Rucaparib in Patients With Platinum-Sensitive, Relapsed, High-Grade Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer (ARIEL2)

Who this might be right for
Ovarian CancerEpithelial Ovarian CancerFallopian Tube Cancer+1 more
pharmaand GmbH 491
Not applicableEnded earlyNCT00615628
What this trial is testing

Inheritance of Osteosarcoma & Paget's Disease Through Chromosome 18:

Who this might be right for
OsteosarcomaPaget's Disease
State University of New York - Upstate Medical University 8
Not applicableLooking for participantsNCT04981119
What this trial is testing

Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing

Who this might be right for
Solid Tumor, AdultColorectal CancerNon Small Cell Lung Cancer+14 more
A2 Biotherapeutics Inc. 200
Large-scale testing (Phase 3)Study completedNCT03287960
What this trial is testing

Setmelanotide for the Treatment of Leptin Receptor (LEPR) Deficiency Obesity

Who this might be right for
Leptin Receptor Deficiency Obesity
Rhythm Pharmaceuticals, Inc. 15
Not applicableUnknownNCT00126958
What this trial is testing

Cost-Effectiveness in Bladder Cancer

Who this might be right for
Bladder Cancer
Erasmus Medical Center 500
Not applicableLooking for participantsNCT00001975
What this trial is testing

Study of Skin Tumors in Tuberous Sclerosis

Who this might be right for
Tuberous Sclerosis
National Heart, Lung, and Blood Institute (NHLBI) 400
Large-scale testing (Phase 3)Active Not RecruitingNCT00626990
What this trial is testing

Phase III Trial of Anaplastic Glioma Without 1p/19q Loss of Heterozygosity (LOH)

Who this might be right for
Brain and Central Nervous System Tumors
European Organisation for Research and Treatment of Cancer - EORTC 751
Early research (Phase 1)Looking for participantsNCT05787587
What this trial is testing

PARG Inhibitor IDE161 in Participants With Advanced Solid Tumors

Who this might be right for
Advanced or Metastatic Solid TumorsBreast CancerOvarian Cancer+6 more
IDEAYA Biosciences 216
Large-scale testing (Phase 3)Study completedNCT02896192
What this trial is testing

Setmelanotide for the Treatment of Early-Onset Pro-Opiomelanocortin (POMC) Deficiency Obesity

Who this might be right for
Pro-opiomelanocortin (POMC) Deficiency Obesity
Rhythm Pharmaceuticals, Inc. 15
Not applicableUnknownNCT03202810
What this trial is testing

Innovative Approach to Triage Oral Precancer

Who this might be right for
Oral CancerOral Premalignant Lesion
British Columbia Cancer Agency 360
Testing effectiveness (Phase 2)Ended earlyNCT03840967
What this trial is testing

A Study Evaluating Safety and Efficacy of Niraparib in Patients With Previously Treated Metastatic Esophageal/Gastroesophageal Junction/Proximal Gastric Adenocarcinoma

Who this might be right for
Esophageal CancerGastric CancerAdenocarcinoma
Shadia Jalal, MD 14
Not applicableActive Not RecruitingNCT05812027
What this trial is testing

A Screening Study to Collect Samples for TAA, HLA & HLA Loss of Heterozygosity in Patients With Metastatic Solid Tumors

Who this might be right for
Head and Neck CancerCervical CancerNon Small Cell Lung Cancer+4 more
TScan Therapeutics, Inc. 1,150
Large-scale testing (Phase 3)Study completedNCT02855944
What this trial is testing

ARIEL4: A Study of Rucaparib Versus Chemotherapy BRCA Mutant Ovarian, Fallopian Tube, or Primary Peritoneal Cancer Patients

Who this might be right for
Ovarian CancerEpithelial Ovarian CancerFallopian Tube Cancer+1 more
pharmaand GmbH 349
Testing effectiveness (Phase 2)Study completedNCT03845296
What this trial is testing

Rucaparib in Treating Patients With Genomic LOH High and/or Deleterious BRCA1/2 Mutation Stage IV or Recurrent Non-small Cell Lung Cancer (A Lung-MAP Treatment Trial)

Who this might be right for
Deleterious BRCA1 Gene MutationDeleterious BRCA2 Gene MutationLoss of Heterozygosity+8 more
SWOG Cancer Research Network 64