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Results for “Lymphohistiocytosis”

114 trials

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Showing 20 of 114 results

Not applicableActive Not RecruitingNCT05236764
What this trial is testing

Haploidentical Hematopoietic Cell Transplantation Using TCR Alpha/Beta and CD19 Depletion

Who this might be right for
Acute Lymphoblastic Leukemia in RemissionAcute Myeloid Leukemia in RemissionMyelodysplastic Syndromes+8 more
Baylor College of Medicine 3
Large-scale testing (Phase 3)Study completedNCT02069899
What this trial is testing

Long-term Follow-up of Hemophagocytic Lymphohistiocytosis (HLH) Participants Who Received Treatment With Emapalumab (NI-0501), an Anti-interferon Gamma Monoclonal Antibody

Who this might be right for
Hemophagocytic Lymphohistiocytosis
Swedish Orphan Biovitrum 58
Testing effectiveness (Phase 2)Study completedNCT00919503
What this trial is testing

Treosulfan and Fludarabine Phosphate Before Donor Stem Cell Transplant in Treating Patients With Nonmalignant Inherited Disorders

Who this might be right for
Non-Neoplastic Hematologic and Lymphocytic Disorder
Fred Hutchinson Cancer Center 98
Testing effectiveness (Phase 2)WithdrawnNCT02007239
What this trial is testing

Tocilizumab and Hemophagocytic Lymphohistiocytosis (HLH)

Who this might be right for
Hemophagocytic Lymphohistiocytosis
Children's Hospital of Philadelphia
Early research (Phase 1)Looking for participantsNCT06135922
What this trial is testing

Clinical Study of EBV-TCR-T Cells for EBV-associated Hemophagocytic Lymphohistiocytosis or EBV Infection

Who this might be right for
EBV-associated Hemophagocytic LymphohistiocytosisEBV Infection
Chinese PLA General Hospital 9
Testing effectiveness (Phase 2)Active Not RecruitingNCT02061800
What this trial is testing

CD34+ (Malignant) Stem Cell Selection for Patients Receiving Allogenic Stem Cell Transplant

Who this might be right for
Chronic Myeloid Leukemia (CML)Acute Myelogenous Leukemia (AML)Myelodysplastic Syndrome (MDS)+3 more
Diane George 14
Large-scale testing (Phase 3)Not Yet RecruitingNCT05775705
What this trial is testing

L-DEP Regimen Combined With PD-1 Antibody as Induction Therapy for Epstein-Barr Virus-positive LA-HLH

Who this might be right for
PD-1 AntibodyHemophagocytic LymphohistiocytosisEpstein-Barr Virus+1 more
Beijing Friendship Hospital 25
Large-scale testing (Phase 3)UnknownNCT03742115
What this trial is testing

Etoposide in the First-line Treatment of Adult EBV-HLH

Who this might be right for
Hemophagocytic Lymphohistiocytosis
Beijing Friendship Hospital 90
Post-approval studies (Phase 4)Looking for participantsNCT07270835
What this trial is testing

Zanubrutinib Combined With Rituximab in the Treatment of Secondary HLH in B-cell Lymphoma

Who this might be right for
Hemophagocytic LymphohistiocytosisB Cell Lymphoma
The First Affiliated Hospital of Soochow University 40
Not applicableStudy completedNCT03546101
What this trial is testing

Early Detection of Epstein-Barr Virus Related Disease.

Who this might be right for
Post-transplant Lymphoproliferative DisorderMononucleosisEpstein-Barr Virus Infections+6 more
University of Aarhus 1,527
Not applicableUnknownNCT00006056
What this trial is testing

Pilot Study of Unrelated Donor Hematopoietic Stem Cell Transplantation in Patients With Life Threatening Hemophagocytic Disorders

Who this might be right for
Chediak-Higashi SyndromeGraft Versus Host DiseaseX-Linked Lymphoproliferative Syndrome+3 more
Fairview University Medical Center 40
Not applicableUnknownNCT05137522
What this trial is testing

Chidamide Combines With VP-16 and Methylprednisolone in the Treatment of HLH

Who this might be right for
ChidamideHemophagocytic Lymphohistiocytosis
Beijing Friendship Hospital 20
Large-scale testing (Phase 3)Study completedNCT05001737
What this trial is testing

Evaluate Efficacy, Safety and Tolerability, PK and PD of Emapalumab in Children and Adults With MAS in Still's or SLE

Who this might be right for
Macrophage Activation SyndromeSecondary Hemophagocytic LymphohistiocytosisStill Disease+4 more
Swedish Orphan Biovitrum 33
Not applicableLooking for participantsNCT04902807
What this trial is testing

Conception of a Diagnosis, Prognosis and Therapeutic Decision Tool for Patients With Autoimmunity and Inflammation

Who this might be right for
Autoimmune Lymphoproliferative SyndromeAutoimmune CytopeniaAutoimmune Diseases+17 more
Institut National de la Santé Et de la Recherche Médicale, France 500
Testing effectiveness (Phase 2)Study completedNCT07034209
What this trial is testing

Evaluate the Efficacy, Safety, Tolerability, Pharmacokinetic Characteristics, and Immunogenicity of Plonmarlimab in Subjects With Rheumatic and Immunological Disease-associated Haemophagocytic Lymphohistiocytosis (HLH) (Also Known as Macrophage Activation Syndrome (MAS))

Who this might be right for
Hemophagocytic Lymphohistiocytoses
TJ Biopharma Co., Ltd. 18
Early research (Phase 1)Active Not RecruitingNCT00710892
What this trial is testing

CASPALLO: Allodepleted T Cells Transduced With Inducible Caspase 9 Suicide Gene

Who this might be right for
Acute Lymphoblastic LeukemiaNon-Hodgkin's LymphomaMyelodysplastic Syndrome+1 more
Baylor College of Medicine 10
Large-scale testing (Phase 3)Ended earlyNCT00176826
What this trial is testing

T-Cell Depletion and Stem Cell Transplant for Immune Deficiencies and Histiocytic Disorders

Who this might be right for
Hemophagocytic LymphohistiocytosisX-Linked Lymphoproliferative DisordersChediak-Higashi Syndrome+4 more
Masonic Cancer Center, University of Minnesota 22
Not applicableLooking for participantsNCT05702502
What this trial is testing

Assessing the Presence of CT-DNA in Lymphoma Associated HLH

Who this might be right for
LymphomaHaemophagocytic Lymphohistiocytosis
Nottingham University Hospitals NHS Trust 12
Early research (Phase 1)UnknownNCT05546060
What this trial is testing

Efficacy and Safety of Venetoclax Combined With Dexamethasone and Etoposide in HLH

Who this might be right for
Hemophagocytic Lymphohistiocytosis
Beijing Friendship Hospital 20
Testing effectiveness (Phase 2)Looking for participantsNCT06160791
What this trial is testing

Ruxolitinib With De-Intensified HLH-94 for the Treatment of Hemophagocytic Lymphohistiocytosis (HLH)

Who this might be right for
Hemophagocytic Lymphohistiocytoses
Jerry Lee, MD, MSc, MPhil 36
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