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Results for “MELAS Syndrome”

38 trials

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Showing 20 of 38 results

Testing effectiveness (Phase 2)Study completedNCT01603446
What this trial is testing

L-arginine Therapy on Endothelium-dependent Vasodilation & Mitochondrial Metabolism in MELAS Syndrome

Who this might be right for
MELAS Syndrome
The Hospital for Sick Children 7
Testing effectiveness (Phase 2)Study completedNCT04165239
What this trial is testing

The KHENERGYZE Study

Who this might be right for
Mitochondrial DiseasesMitochondrial MyopathiesMitochondrial Encephalomyopathies+2 more
Khondrion BV 27
Not applicableUnknownNCT02114554
What this trial is testing

Mitochondrial nt3243 A>G Mutation in Taiwan

Who this might be right for
MELAS SyndromeNoninsulin-dependent Diabetes Mellitus With Deafness
National Taiwan University Hospital 40
Testing effectiveness (Phase 2)Study completedNCT00887562
What this trial is testing

Study of Idebenone in the Treatment of Mitochondrial Encephalopathy Lactic Acidosis & Stroke-like Episodes

Who this might be right for
MELAS Syndrome
Michio Hirano 27
Testing effectiveness (Phase 2)UnknownNCT00068913
What this trial is testing

Evaluating the Effectiveness of a Dichloroacetate in MELAS Syndrome

Who this might be right for
MELAS Syndrome
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) 35
Not applicableNo Longer AvailableNCT01370447
What this trial is testing

EPI-743 for Mitochondrial Respiratory Chain Diseases

Who this might be right for
Mitochondrial Diseases
PTC Therapeutics
Testing effectiveness (Phase 2)Ended earlyNCT04475549
What this trial is testing

Phase 2a Study of IW-6463 in Adults Diagnosed With Mitochondrial Encephalomyopathy, Lactic Acidosis, and Stroke-like Episodes (MELAS)

Who this might be right for
MELAS
Tisento Therapeutics 8
Testing effectiveness (Phase 2)Study completedNCT06051448
What this trial is testing

Promoting Resilience in Stress Management (PRISM) and Clinical-focused Narrative (CFN) Pilot in Adults With Primary Mitochondrial Disease (PMD).

Who this might be right for
Mitochondrial DiseasesMitochondrial MyopathiesMitochondrial Encephalomyopathies+2 more
Children's Hospital of Philadelphia 16
Early research (Phase 1)Study completedNCT03056209
What this trial is testing

Safety, Tolerability and Pharmacokinetic Study of KL1333 in Healthy Male Volunteers

Who this might be right for
MELAS SyndromeMitochondrial Respiratory Chain Deficiencies
Yungjin Pharm. Co., Ltd. 60
Not applicableLooking for participantsNCT05554835
What this trial is testing

Global Registry and Natural History Study for Mitochondrial Disorders

Who this might be right for
Mitochondrial DiseasesKearns-Sayre SyndromeMIDD+15 more
LMU Klinikum 6,000
Not applicableUnknownNCT05255328
What this trial is testing

Clinical Long Term Evaluation of Glutamine Supplement in MELAS Syndrome

Who this might be right for
MELAS Syndrome
Hospital Universitario 12 de Octubre 9
Post-approval studies (Phase 4)Study completedNCT01831934
What this trial is testing

Responses to Influenza Vaccine in Patients With Mitochondrial Disorders (MELAS)

Who this might be right for
MELAS Syndrome
Stanford University 22
Testing effectiveness (Phase 2)Study completedNCT02909400
What this trial is testing

The KHENERGY Study

Who this might be right for
Mitochondrial DiseasesMitochondrial MyopathiesMitochondrial Encephalomyopathies+2 more
Khondrion BV 20
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06792500
What this trial is testing

A Basket Clinical Study to Assess Glycerol Tributyrate in Patients With Mitochondrial Encephalopathy, Lactic Acidosis, Stroke-like Episodes (MELAS) or Leber's Hereditary Optic Neuropathy-Plus (LHON-Plus)

Who this might be right for
MELAS SyndromeLebers Hereditory Optic Neuropathy With Extra Ocular Symptoms (LHON-Plus)
George Washington University 24
Early research (Phase 1)Study completedNCT03888716
What this trial is testing

A Phase Ia/Ib, SAD and MAD Study of of KL1333 in Healthy Subjects and Patients With Primary Mitochondrial Disease

Who this might be right for
Mitochondrial DiseasesMitochondrial Respiratory Chain DeficienciesMELAS Syndrome+1 more
Abliva AB 72
Testing effectiveness (Phase 2)Study completedNCT06402123
What this trial is testing

A Phase 2b Study of Zagociguat in Patients With MELAS

Who this might be right for
Mitochondrial Encephalopathy, Lactic Acidosis and Stroke-Like Episodes (MELAS Syndrome)
Tisento Therapeutics 43
Large-scale testing (Phase 3)Study completedNCT05218655
What this trial is testing

A Safety Study for Previously Treated Vatiquinone (PTC743) Participants With Inherited Mitochondrial Disease

Who this might be right for
Inherited Mitochondrial Disease
PTC Therapeutics 101
Testing effectiveness (Phase 2)Ended earlyNCT02473445
What this trial is testing

A Long-term Extension of Study RP103-MITO-001 (NCT02023866) to Assess Cysteamine Bitartrate Delayed-release Capsules (RP103) in Children With Inherited Mitochondrial Disease

Who this might be right for
Mitochondrial Diseases
Amgen 22
Testing effectiveness (Phase 2)Study completedNCT05972954
What this trial is testing

OMT-28 in Patients With Primary Mitochondrial Disease (PMD) (PMD-OPTION)

Who this might be right for
Primary Mitochondrial Disease
Omeicos Therapeutics GmbH 28
Very early researchStudy completedNCT01339494
What this trial is testing

Nitric Oxide Production in MELAS Syndrome

Who this might be right for
MELAS Syndrome
Baylor College of Medicine 30
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