Not applicableEnded earlyNCT05605587What this trial is testingLeflunomide Treatment for MEN1 Patients - the LUMEN1 TrialWho this might be right forMEN1 Gene Mutation University Hospital, Basel, Switzerland 3
Early research (Phase 1)Looking for participantsNCT05735184What this trial is testingInvestigate the Safety and Tolerability of Ziftomenib in Combination With Venetoclax/Azacitidine, Venetoclax, 7+3, or 7+3+Quizartinib in Patients With AMLWho this might be right forAcute Myeloid LeukemiaMixed Lineage Leukemia Gene MutationRefractory AML+7 more Kura Oncology, Inc. 420
Testing effectiveness (Phase 2)Ended earlyNCT02315625What this trial is testingStudy of Mutation-Targeted Therapy With Sunitinib or Everolimus in People With Advanced Low- or Intermediate-Grade Neuroendocrine Tumors of the Gastrointestinal Tract and Pancreas With or Without Cytoreductive SurgeryWho this might be right forNeuroendocrine TumorsNeuroendocrine CarcinomaNeuroendocrine Neoplasms+2 more National Cancer Institute (NCI) 16
Testing effectiveness (Phase 2)Looking for participantsNCT04988555What this trial is testingEnzomenib (DSP-5336) in Patients With Acute Leukemia (Horizen-1)Who this might be right forLeukemia, Myeloid, AcuteLeukemia, Lymphocytic, AcuteMultiple Myeloma+1 more Sumitomo Pharma America, Inc. 606
Early research (Phase 1)Study completedNCT05326516What this trial is testingRevumenib in Combination With Chemotherapy in Participants With R/R Acute LeukemiaWho this might be right forRelapsed/Refractory LeukemiasAcute Lymphoblastic LeukemiaAcute Lymphocytic Leukemia+3 more Syndax Pharmaceuticals 30
Not applicableLooking for participantsNCT07559695What this trial is testingA Real-world Study on the Efficacy and Safety of Menin Inhibitors as Maintenance After Allo-HSCTWho this might be right forMenin InhibitorsAcute LeukemiaPost Hematopoietic Stem Cell Transplantation+4 more The First Affiliated Hospital of Soochow University 20
Early research (Phase 1)Looking for participantsNCT07270770What this trial is testingBY002 IIT Study in R/R Acute LeukemiaWho this might be right forAcute LeukemiaKMT2A Rearrangements or NPM1 Mutations Acute Leukemia The First Affiliated Hospital of Soochow University 18
Not applicableEnded earlyNCT03044600What this trial is testingGene Expression in HyperparathyroidismWho this might be right forParathyroid DiseaseHyperparathyroidism M.D. Anderson Cancer Center 22
Testing effectiveness (Phase 2)Study completedNCT04300790What this trial is testingStudy to Evaluate the Effect of Metformin in the Prevention of HG in HR[+]/HER2[-] PIK3CA-mut Advanced BC PatientsWho this might be right forBreast Cancer MedSIR 69
Post-approval studies (Phase 4)Study completedNCT05631795What this trial is testingStudy to Assess the Safety of Alpelisib Plus Fulvestrant, in Men and Post-menopausal Women With HR-positive, HER2-negative, Advanced Breast Cancer (aBC) With PIK3CA Mutation, Whose Disease Progressed on or After Endocrine TreatmentWho this might be right forAdvanced Breast Cancer Novartis Pharmaceuticals 40
Testing effectiveness (Phase 2)Active Not RecruitingNCT06052813What this trial is testingBN104 in the Treatment of Acute LeukemiaWho this might be right forALL, AdultAML, AdultAcute Leukaemia+4 more Institut de Recherches Internationales Servier (I.R.I.S.) 66
Early research (Phase 1)Looking for participantsNCT06222580What this trial is testingSNDX-5613 and Gilteritinib for the Treatment of Relapsed or Refractory FLT3-Mutated Acute Myeloid Leukemia and Concurrent MLL-Rearrangement or NPM1 MutationWho this might be right forAcute Myeloid Leukemia With FLT3/ITD MutationAcute Myeloid Leukemia With KMT2A RearrangementAcute Myeloid Leukemia With NPM1 Mutation+2 more Uma Borate 30
Not applicableLooking for participantsNCT01793168What this trial is testingRare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at SanfordWho this might be right forRare DisordersUndiagnosed DisordersDisorders of Unknown Prevalence+340 more Sanford Health 20,000
Not applicableLooking for participantsNCT06430021What this trial is testingStudy of the Value of hPG80 (Circulating Progastrin) for the Diagnosis of Neuroendocrine Tumours in Patients With an MEN1 MutationWho this might be right forNeuroendocrine TumorsMEN1 Mutation Centre Hospitalier Universitaire Dijon 297
Not applicableStudy completedNCT02957981What this trial is testingThe Genetic Education for Men Trial: Web-Based Education vs. Standard CareWho this might be right forProstate CarcinomaBreast NeoplasmPancreatic Cancer+2 more Georgetown University 63
Early research (Phase 1)Looking for participantsNCT05886049What this trial is testingA Phase 1b Study of Menin Inhibitor SNDX- 5613 in Combination With Daunorubicin and Cytarabine in Newly Diagnosed Patients With Acute Myeloid Leukemia and NPM1 Mutated/FLT3 Wildtype or MLL/KMT2A Rearranged or NUP98 Alterations DiseaseWho this might be right forAcute Myeloid LeukemiaAcute Myeloid Leukemia With KMT2A RearrangementAcute Myeloid Leukemia With NPM1 Mutation+1 more National Cancer Institute (NCI) 38
Not applicableUnknownNCT00672269What this trial is testingStudy Investigating MEN1 and SDHD in Familial Carcinoid TumorsWho this might be right forCarcinoid Neuroendocrine Cancer Rutgers University 25
Large-scale testing (Phase 3)Looking for participantsNCT07007312What this trial is testingStudies to Assess Ziftomenib in Combination With Ven+Aza or 7+3 in Patients With Untreated NPM1-m or KMT2A-r AMLWho this might be right forAcute Myeloid Leukemia (AML) Kura Oncology, Inc. 1,300
Testing effectiveness (Phase 2)Looking for participantsNCT07101497What this trial is testingPhase 2 Trial of BN104 as Post-HSCT Maintenance in Acute LeukemiaWho this might be right forMenin InhibitorsPost Hematopoietic Stem Cell TransplantationMaintenance Therapy+4 more The First Affiliated Hospital of Soochow University 60
Early research (Phase 1)Ended earlyNCT05153330What this trial is testingStudy of BMF-219, a Covalent Menin Inhibitor, in Adult Patients With AML, ALL (With KMT2A/ MLL1r, NPM1 Mutations), DLBCL, MM, and CLL/SLLWho this might be right forAcute Myeloid LeukemiaAcute Lymphoblastic LeukemiaAcute Mixed-Phenotype Leukemia+12 more Biomea Fusion Inc. 55