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Results for “MGMT-Unmethylated Glioblastoma”

45 trials

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Showing 20 of 45 results

Early research (Phase 1)Ended earlyNCT03250299
What this trial is testing

Microtubule-Targeted Agent BAL101553 and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma

Who this might be right for
GlioblastomaMGMT-Unmethylated Glioblastoma
Basilea Pharmaceutica 26
Testing effectiveness (Phase 2)Looking for participantsNCT07185880
What this trial is testing

The Safety and Tolerability of MT-125 in GBM Patients

Who this might be right for
Glioblastoma (GBM)
Myosin Therapeutics Inc. 36
Testing effectiveness (Phase 2)Looking for participantsNCT06504381
What this trial is testing

DB107-RRV, DB107-FC, and Radiation Therapy With or Without Temozolomide (TMZ) for High Grade Glioma

Who this might be right for
High Grade GliomaMGMT-Unmethylated GlioblastomaMGMT-Methylated Glioblastoma
University of California, San Francisco 70
Testing effectiveness (Phase 2)Active Not RecruitingNCT05986851
What this trial is testing

Azeliragon in MGMT Unmethylated Glioblastoma

Who this might be right for
Glioblastoma
Cantex Pharmaceuticals 30
Testing effectiveness (Phase 2)UnknownNCT04725214
What this trial is testing

Anlotinib Combined With STUPP for MGMT Nonmethylated Glioblastoma

Who this might be right for
MGMT-Unmethylated Glioblastoma
Second Affiliated Hospital, School of Medicine, Zhejiang University 33
Testing effectiveness (Phase 2)Ended earlyNCT01044225
What this trial is testing

Effect of Radiation Therapy Plus Temozolomide Combined With Cilengitide or Cetuximab on the 1-year Overall Survival of Patients With Newly Diagnosed MGMT-promoter Unmethylated Glioblastoma

Who this might be right for
Glioblastoma
Bart Neyns 12
Testing effectiveness (Phase 2)Study completedNCT03367715
What this trial is testing

Nivolumab, Ipilimumab, and Short-course Radiotherapy in Adults With Newly Diagnosed, MGMT Unmethylated Glioblastoma

Who this might be right for
MGMT-unmethylated Glioblastoma (GBM)GBM
NYU Langone Health 10
Large-scale testing (Phase 3)Not Yet RecruitingNCT07452458
What this trial is testing

Temporally-Modulated Pulsed Radiation Therapy Versus Standard Radiation Therapy for the Treatment of Newly Diagnosed, IDH Wildtype, MGMT-Unmethylated Glioblastoma

Who this might be right for
Glioblastoma, IDH-WildtypeMGMT-Unmethylated Glioblastoma
NRG Oncology 398
Early research (Phase 1)Study completedNCT05938387
What this trial is testing

Safety and Tolerability of CVGBM in Adults With Newly Diagnosed MGMT-Unmethylated Glioblastoma or Astrocytoma

Who this might be right for
Glioblastoma
CureVac 37
Very early researchStudy completedNCT05432375
What this trial is testing

Study of Tinostamustine for Adjuvant Treatment of Glioblastoma

Who this might be right for
Glioblastoma Multiforme
Mundipharma Research Limited 10
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07347210
What this trial is testing

Evaluation of UCPVax Vaccine +/- Pembrolizumab Combined With Standard Treatment as Adjuvant Therapy in Patients With Unmethylated MGMT Glioblastoma

Who this might be right for
Primary Glioblastoma
Centre Hospitalier Universitaire de Besancon 98
Testing effectiveness (Phase 2)Ended earlyNCT06359379
What this trial is testing

Ropidoxuridine as a Radiosensitizer in Newly Diagnosed IDH-Wildtype Glioblastoma With Unmethylated MGMT Promoter

Who this might be right for
Glioblastoma, IDH-wildtype
Shuttle Pharmaceuticals, Inc. 30
Early research (Phase 1)Ended earlyNCT03107780
What this trial is testing

Testing the Ability of AMG 232 (KRT 232) to Get Into the Tumor in Patients With Brain Cancer

Who this might be right for
GlioblastomaGliosarcomaMGMT-Unmethylated Glioblastoma+1 more
National Cancer Institute (NCI) 32
Early research (Phase 1)Study completedNCT03726515
What this trial is testing

CART-EGFRvIII + Pembrolizumab in GBM

Who this might be right for
Glioblastoma
University of Pennsylvania 7
Testing effectiveness (Phase 2)Looking for participantsNCT05734560
What this trial is testing

D2C7-IT and 2141-V11 in Newly Diagnosed GBM Patients

Who this might be right for
Newly Diagnosed MGMT Unmethylated Glioblastoma
Darell Bigner 50
Testing effectiveness (Phase 2)Study completedNCT02717962
What this trial is testing

Study of VAL-083 in Patients With MGMT Unmethylated, Bevacizumab-naive Glioblastoma in the Adjuvant or Recurrent Setting

Who this might be right for
GliomaGlioblastomaGlioblastoma Multiforme+2 more
Kintara Therapeutics, Inc. 118
Early research (Phase 1)Active Not RecruitingNCT05743595
What this trial is testing

Neoantigen-based Personalized DNA Vaccine With Retifanlimab PD-1 Blockade Therapy in Patients With Newly Diagnosed, Unmethylated Glioblastoma

Who this might be right for
Unmethylated Glioblastoma
Washington University School of Medicine 27
Testing effectiveness (Phase 2)UnknownNCT04224441
What this trial is testing

Repurposing Chlorpromazine in the Treatment of Glioblastoma

Who this might be right for
Glioblastoma MultiformeMGMT-Unmethylated Glioblastoma
Marco G Paggi, MD, PhD 41
Early research (Phase 1)Looking for participantsNCT06186401
What this trial is testing

Anti-EGFRvIII synNotch Receptor Induced Anti-EphA2/IL-13Ralpha2 CAR (E-SYNC) T Cells

Who this might be right for
EGFR Gene MutationGlioblastomaMGMT-Unmethylated Glioblastoma+1 more
Hideho Okada, MD, PhD 20
Testing effectiveness (Phase 2)Looking for participantsNCT05909618
What this trial is testing

Crizanlizumab Alone or in Combination With Nivolumab for Glioblastoma and Melanoma With Brain Metastases

Who this might be right for
Advanced GlioblastomaMetastatic Melanoma in the Central Nervous SystemMGMT-Unmethylated Glioblastoma
Sheba Medical Center 33
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