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Results for “MGMT-Unmethylated Glioblastoma”

43 trials

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Showing 20 of 43 results

Early research (Phase 1)Active Not RecruitingNCT05236036
What this trial is testing

Mycophenolate Mofetil in Combination With Standard of Care for the Treatment of Glioblastoma

Who this might be right for
AstrocytomaGlioblastomaGlioblastoma, IDH-Wildtype+2 more
Northwestern University 60
Testing effectiveness (Phase 2)Looking for participantsNCT05871021
What this trial is testing

Protective VEGF Inhibition for Isotoxic Dose Escalation in Glioblastoma

Who this might be right for
Glioblastoma
University Hospital Tuebingen 146
Early research (Phase 1)Study completedNCT03452930
What this trial is testing

Tinostamustine With or Without Radiation Therapy in Treating Patients With Newly Diagnosed MGMT-Unmethylated Glioblastoma

Who this might be right for
GlioblastomaGliosarcomaMGMT-Unmethylated Glioblastoma
M.D. Anderson Cancer Center 5
Early research (Phase 1)Looking for participantsNCT04555577
What this trial is testing

Peposertib and Radiation Therapy, Followed by Temozolomide for the Treatment of Patients With Newly Diagnosed MGMT Unmethylated Glioblastoma or Gliosarcoma

Who this might be right for
GlioblastomaGliosarcoma
M.D. Anderson Cancer Center 29
Testing effectiveness (Phase 2)Looking for participantsNCT05879250
What this trial is testing

WP1066 and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma

Who this might be right for
Glioblastoma, IDH-WildtypeMGMT-Unmethylated Glioblastoma
Northwestern University 39
Testing effectiveness (Phase 2)Study completedNCT03367715
What this trial is testing

Nivolumab, Ipilimumab, and Short-course Radiotherapy in Adults With Newly Diagnosed, MGMT Unmethylated Glioblastoma

Who this might be right for
MGMT-unmethylated Glioblastoma (GBM)GBM
NYU Langone Health 10
Large-scale testing (Phase 3)Looking for participantsNCT06388733
What this trial is testing

A Study Comparing Niraparib With Temozolomide in Adult Participants With Newly-diagnosed, MGMT Unmethylated Glioblastoma

Who this might be right for
GlioblastomaGBMBrain Neoplasms, Adult, Malignant+1 more
Ivy Brain Tumor Center 450
Testing effectiveness (Phase 2)UnknownNCT05033587
What this trial is testing

Study of AK105 With Anlotinib and Radiotherapy Adjuvant Therapy in MGMT Unmethylated Newly Diagnosed Glioblastoma.

Who this might be right for
MGMT-Unmethylated Glioblastoma
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School 28
Early research (Phase 1)Looking for participantsNCT06973096
What this trial is testing

CART-EGFR-IL13Ra2 in Newly Diagnosed GBM Following Initial Radiotherapy

Who this might be right for
Glioblastoma
University of Pennsylvania 9
Testing effectiveness (Phase 2)Looking for participantsNCT05909618
What this trial is testing

Crizanlizumab Alone or in Combination With Nivolumab for Glioblastoma and Melanoma With Brain Metastases

Who this might be right for
Advanced GlioblastomaMetastatic Melanoma in the Central Nervous SystemMGMT-Unmethylated Glioblastoma
Sheba Medical Center 33
Testing effectiveness (Phase 2)Looking for participantsNCT06504381
What this trial is testing

DB107-RRV, DB107-FC, and Radiation Therapy With or Without Temozolomide (TMZ) for High Grade Glioma

Who this might be right for
High Grade GliomaMGMT-Unmethylated GlioblastomaMGMT-Methylated Glioblastoma
University of California, San Francisco 70
Large-scale testing (Phase 3)Active Not RecruitingNCT04396860
What this trial is testing

Testing the Use of the Immunotherapy Drugs Ipilimumab and Nivolumab Plus Radiation Therapy Compared to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed MGMT Unmethylated Glioblastoma

Who this might be right for
GliosarcomaMGMT-Unmethylated Glioblastoma
National Cancer Institute (NCI) 159
Testing effectiveness (Phase 2)Study completedNCT02717962
What this trial is testing

Study of VAL-083 in Patients With MGMT Unmethylated, Bevacizumab-naive Glioblastoma in the Adjuvant or Recurrent Setting

Who this might be right for
GliomaGlioblastomaGlioblastoma Multiforme+2 more
Kintara Therapeutics, Inc. 118
Testing effectiveness (Phase 2)Ended earlyNCT01044225
What this trial is testing

Effect of Radiation Therapy Plus Temozolomide Combined With Cilengitide or Cetuximab on the 1-year Overall Survival of Patients With Newly Diagnosed MGMT-promoter Unmethylated Glioblastoma

Who this might be right for
Glioblastoma
Bart Neyns 12
Early research (Phase 1)Study completedNCT03726515
What this trial is testing

CART-EGFRvIII + Pembrolizumab in GBM

Who this might be right for
Glioblastoma
University of Pennsylvania 7
Testing effectiveness (Phase 2)Active Not RecruitingNCT04121455
What this trial is testing

Glioblastoma Treatment With Irradiation and Olaptesed Pegol (NOX-A12) in MGMT Unmethylated Patients

Who this might be right for
Glioblastoma
TME Pharma AG 117
Large-scale testing (Phase 3)Looking for participantsNCT03970447
What this trial is testing

A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent Glioblastoma

Who this might be right for
Glioblastoma
Global Coalition for Adaptive Research 1,280
Early research (Phase 1)Ended earlyNCT03107780
What this trial is testing

Testing the Ability of AMG 232 (KRT 232) to Get Into the Tumor in Patients With Brain Cancer

Who this might be right for
GlioblastomaGliosarcomaMGMT-Unmethylated Glioblastoma+1 more
National Cancer Institute (NCI) 32
Testing effectiveness (Phase 2)Study completedNCT03522298
What this trial is testing

Safety, Pharmacokinetics and Efficacy of Paxalisib (GDC-0084) in Newly-diagnosed Glioblastoma

Who this might be right for
Glioblastoma, Adult
Kazia Therapeutics Limited 30
Early research (Phase 1)Ended earlyNCT03250299
What this trial is testing

Microtubule-Targeted Agent BAL101553 and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma

Who this might be right for
GlioblastomaMGMT-Unmethylated Glioblastoma
Basilea Pharmaceutica 26
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