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Results for “MGMT-unmethylated Glioblastoma (GBM)”

43 trials

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Showing 20 of 43 results

Testing effectiveness (Phase 2)UnknownNCT02928575
What this trial is testing

Combining Sunitinib, Temozolomide and Radiation to Treat Patients Diagnosed With Glioblastoma

Who this might be right for
Glioblastoma Multiforme
Bassam Abdulkarim 45
Testing effectiveness (Phase 2)Study completedNCT02717962
What this trial is testing

Study of VAL-083 in Patients With MGMT Unmethylated, Bevacizumab-naive Glioblastoma in the Adjuvant or Recurrent Setting

Who this might be right for
GliomaGlioblastomaGlioblastoma Multiforme+2 more
Kintara Therapeutics, Inc. 118
Early research (Phase 1)Study completedNCT03726515
What this trial is testing

CART-EGFRvIII + Pembrolizumab in GBM

Who this might be right for
Glioblastoma
University of Pennsylvania 7
Testing effectiveness (Phase 2)Active Not RecruitingNCT04121455
What this trial is testing

Glioblastoma Treatment With Irradiation and Olaptesed Pegol (NOX-A12) in MGMT Unmethylated Patients

Who this might be right for
Glioblastoma
TME Pharma AG 117
Testing effectiveness (Phase 2)Study completedNCT00813943
What this trial is testing

Cilengitide, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma and Unmethylated Gene Promoter Status

Who this might be right for
Glioblastoma
EMD Serono 265
Testing effectiveness (Phase 2)Ended earlyNCT06359379
What this trial is testing

Ropidoxuridine as a Radiosensitizer in Newly Diagnosed IDH-Wildtype Glioblastoma With Unmethylated MGMT Promoter

Who this might be right for
Glioblastoma, IDH-wildtype
Shuttle Pharmaceuticals, Inc. 30
Testing effectiveness (Phase 2)UnknownNCT06186440
What this trial is testing

Cisplatin Plus Temozolomide Compared With Temozolomide in Patients With MGMT Promotor Unmethylated Glioblastoma

Who this might be right for
Glioblastoma Multiforme of Brain
Zhongnan Hospital 60
Testing effectiveness (Phase 2)UnknownNCT05694416
What this trial is testing

Etoposide Plus Cisplatin Compared With Temozolomide in Patients With Glioblastoma

Who this might be right for
MGMT-Unmethylated Glioblastoma
Zhongnan Hospital 60
Testing effectiveness (Phase 2)Study completedNCT03367715
What this trial is testing

Nivolumab, Ipilimumab, and Short-course Radiotherapy in Adults With Newly Diagnosed, MGMT Unmethylated Glioblastoma

Who this might be right for
MGMT-unmethylated Glioblastoma (GBM)GBM
NYU Langone Health 10
Early research (Phase 1)Looking for participantsNCT04555577
What this trial is testing

Peposertib and Radiation Therapy, Followed by Temozolomide for the Treatment of Patients With Newly Diagnosed MGMT Unmethylated Glioblastoma or Gliosarcoma

Who this might be right for
GlioblastomaGliosarcoma
M.D. Anderson Cancer Center 29
Testing effectiveness (Phase 2)Active Not RecruitingNCT05986851
What this trial is testing

Azeliragon in MGMT Unmethylated Glioblastoma

Who this might be right for
Glioblastoma
Cantex Pharmaceuticals 30
Early research (Phase 1)Looking for participantsNCT05743595
What this trial is testing

Neoantigen-based Personalized DNA Vaccine With Retifanlimab PD-1 Blockade Therapy in Patients With Newly Diagnosed, Unmethylated Glioblastoma

Who this might be right for
Unmethylated Glioblastoma
Washington University School of Medicine 27
Early research (Phase 1)Study completedNCT03452930
What this trial is testing

Tinostamustine With or Without Radiation Therapy in Treating Patients With Newly Diagnosed MGMT-Unmethylated Glioblastoma

Who this might be right for
GlioblastomaGliosarcomaMGMT-Unmethylated Glioblastoma
M.D. Anderson Cancer Center 5
Testing effectiveness (Phase 2)UnknownNCT04224441
What this trial is testing

Repurposing Chlorpromazine in the Treatment of Glioblastoma

Who this might be right for
Glioblastoma MultiformeMGMT-Unmethylated Glioblastoma
Marco G Paggi, MD, PhD 41
Testing effectiveness (Phase 2)Study completedNCT03522298
What this trial is testing

Safety, Pharmacokinetics and Efficacy of Paxalisib (GDC-0084) in Newly-diagnosed Glioblastoma

Who this might be right for
Glioblastoma, Adult
Kazia Therapeutics Limited 30
Large-scale testing (Phase 3)Study completedNCT02617589
What this trial is testing

An Investigational Immuno-therapy Study of Nivolumab Compared to Temozolomide, Each Given With Radiation Therapy, for Newly-diagnosed Patients With Glioblastoma (GBM, a Malignant Brain Cancer)

Who this might be right for
Brain Cancer
Bristol-Myers Squibb 560
Testing effectiveness (Phase 2)Looking for participantsNCT03643549
What this trial is testing

Bortezomib and Temozolomide in Recurrent Grade-4 Glioma Unmethylated MGMT Promoter (BORTEM-17)

Who this might be right for
Glioblastoma
Haukeland University Hospital 63
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07326566
What this trial is testing

Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIII

Who this might be right for
Glioblastoma (GBM)Newly Diagnosed GlioblastomaGBM+4 more
Black Diamond Therapeutics, Inc. 162
Testing effectiveness (Phase 2)UnknownNCT04725214
What this trial is testing

Anlotinib Combined With STUPP for MGMT Nonmethylated Glioblastoma

Who this might be right for
MGMT-Unmethylated Glioblastoma
Second Affiliated Hospital, School of Medicine, Zhejiang University 33
Early research (Phase 1)WithdrawnNCT04741984
What this trial is testing

Monocyte Antigen Carrier Cells for Newly Diagnosed GBM

Who this might be right for
GlioblastomaGlioma, Malignant
Michael Gunn
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