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Results for “MLH1 Gene Mutation”

13 trials

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Showing 13 of 13 results

Not applicableActive Not RecruitingNCT00261456
What this trial is testing

The IMPACT Study - Identification of Men With a Genetic Predisposition to ProstAte Cancer

Who this might be right for
Prostate CancerBRCA MutationMismatch Repair Gene Mutation+1 more
Institute of Cancer Research, United Kingdom 3,500
Not applicableLooking for participantsNCT07472686
What this trial is testing

Small Bowel Capsule Endoscopy in Lynch Syndrome

Who this might be right for
MMR MutationSmall Bowel AdenomaSmall-bowel Adenocarcinoma+2 more
Assistance Publique - Hôpitaux de Paris 400
Not applicableActive Not RecruitingNCT04009148
What this trial is testing

Cascade Testing in Families With Newly Diagnosed Hereditary Breast and Ovarian Cancer Syndrome

Who this might be right for
BRCA-Mutated Ovarian CarcinomaBRIP1 Gene MutationMSH2 A636P+5 more
NYU Langone Health 118
Testing effectiveness (Phase 2)Ended earlyNCT03631641
What this trial is testing

Nivolumab in Preventing Colon Adenomas in Participants With Lynch Syndrome and a History of Partial Colectomy

Who this might be right for
Colon AdenomaColon CarcinomaLynch Syndrome+2 more
John Hays 3
Not applicableStudy completedNCT04976439
What this trial is testing

Patogenic Mutation in 5 Genes

Who this might be right for
Colorectal CancerAPC Gene MutationTP53 Gene Mutation+3 more
Dr Cipto Mangunkusumo General Hospital 22
Early research (Phase 1)Study completedNCT03005002
What this trial is testing

Durvalumab and Tremelimumab in Treating Patients With Microsatellite Stable Metastatic Colorectal Cancer to the Liver

Who this might be right for
Metastatic Carcinoma in the LiverMLH1 Gene MutationMSH6 Gene Mutation+4 more
City of Hope Medical Center 9
Not applicableLooking for participantsNCT07450612
What this trial is testing

Liquid Biopsy and Machine Learning for Early Colorectal Cancer, Adenomas, Lynch Cancers, and Residual Disease Detection

Who this might be right for
Colorectal CancerAdenoma ColonAdenoma Colon Polyp+16 more
San Raffaele University 1,200
Not applicableLooking for participantsNCT06708429
What this trial is testing

Lynch Syndrome X-Talk of Enteral Mucosa With Immune System

Who this might be right for
Lynch SyndromeLynch Syndrome ILynch Syndrome II+19 more
San Raffaele University 300
Not applicableTemporarily pausedNCT02993068
What this trial is testing

Stand up to Cancer: MAGENTA (Making Genetic Testing Accessible)

Who this might be right for
BARD1 Gene MutationBRCA1 Gene MutationBRCA2 Gene Mutation+12 more
M.D. Anderson Cancer Center 5,200
Not applicableLooking for participantsNCT05420064
What this trial is testing

An Intervention to Increase Genetic Testing in Families Who May Share a Gene Mutation Related to Cancer Risk and An Intervention to Help Patients and Their Primary Care Providers Stay Up-to-date About Uncertain Genetic Test Results

Who this might be right for
BRCA1 MutationPOLD1 Gene MutationCDKN2A Mutation+19 more
Memorial Sloan Kettering Cancer Center 1,000
Not applicableActive Not RecruitingNCT02760849
What this trial is testing

Surgery in Preventing Ovarian Cancer in Patients With Genetic Mutations

Who this might be right for
Deleterious BARD1 Gene MutationDeleterious BRCA1 Gene MutationDeleterious BRCA2 Gene Mutation+11 more
M.D. Anderson Cancer Center 374
Not applicableLooking for participantsNCT05704010
What this trial is testing

Videocapsule Endoscopy in Lynch Syndrome

Who this might be right for
Lynch SyndromeLynch Syndrome ILynch Syndrome II+5 more
San Raffaele University 100
Not applicableLooking for participantsNCT06982768
What this trial is testing

How Epigenetic Changes in hMLH1 Connect Lab Research With Diagnosis in Gastric Cancer

Who this might be right for
Gastrectomy for Gastric CancerGastrectomyMLH1 Gene Mutation+1 more
Fondazione Policlinico Universitario Agostino Gemelli IRCCS 245