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Results for “MPAL”

69 trials

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Showing 20 of 69 results

Testing effectiveness (Phase 2)Looking for participantsNCT07356154
What this trial is testing

Revumenib and Mezigdomide in People With Leukemia

Who this might be right for
LeukemiaAcute LeukemiaRelapse Leukemia+5 more
Memorial Sloan Kettering Cancer Center 52
Testing effectiveness (Phase 2)Active Not RecruitingNCT04904588
What this trial is testing

HLA-Mismatched Unrelated Donor Hematopoietic Cell Transplantation With Post-Transplantation Cyclophosphamide

Who this might be right for
Acute Lymphoblastic LeukemiaAcute Myelogenous LeukemiaMixed Phenotype Acute Leukemia+5 more
Center for International Blood and Marrow Transplant Research 300
Testing effectiveness (Phase 2)Looking for participantsNCT07012447
What this trial is testing

Venetoclax + Azacytidine for Newly Diagnosed ETP-like ALL and T-ALL With Myeloid Mutations

Who this might be right for
Early T Acute Lymphoblastic LeukemiaT-Acute Lymphoblastic LeukemiaMixed Phenotype Acute Leukemia, T/Myeloid, Nos
yuejun Liu 32
Testing effectiveness (Phase 2)Looking for participantsNCT06533579
What this trial is testing

Gene Therapy for CD19-Positive Hematologic Malignancies (SENTRY-CD19)

Who this might be right for
B-cell Acute Lymphoblastic LeukemiaLarge B-cell LymphomaChronic Lymphocytic Leukemia+10 more
Vironexis Biotherapeutics Inc. 32
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07819396
What this trial is testing

Depletion of CD45RA Positive Naive T Cells for the Prevention of Graft Versus Host Disease in Older Patients Undergoing Allogeneic Hematopoietic Cell Transplantation for Acute Leukemia or Myelodysplastic Syndrome

Who this might be right for
Acute Biphenotypic LeukemiaAcute LeukemiaAcute Leukemia of Ambiguous Lineage+11 more
Fred Hutchinson Cancer Center 52
Testing effectiveness (Phase 2)Study completedNCT00723099
What this trial is testing

Donor Umbilical Cord Blood Transplant in Treating Patients With Hematologic Cancer

Who this might be right for
Acute Lymphoblastic LeukemiaAcute Myeloid LeukemiaAggressive Non-Hodgkin Lymphoma+23 more
Fred Hutchinson Cancer Center 73
Testing effectiveness (Phase 2)WithdrawnNCT05320380
What this trial is testing

The Drug IMGN632 in Children With Leukemia That Has Come Back After Treatment or is Difficult to Treat

Who this might be right for
Recurrent Acute Myeloid LeukemiaRecurrent B Acute Lymphoblastic LeukemiaRecurrent Mixed Phenotype Acute Leukemia+5 more
Children's Oncology Group
Not applicableNot Yet RecruitingNCT07008027
What this trial is testing

Real World Asparaginase Therapy Toxicity

Who this might be right for
Drug Toxicity
St. Jude Children's Research Hospital 200
Testing effectiveness (Phase 2)Study completedNCT05433532
What this trial is testing

Study of Azacitidine，Venetoclax，and Flumatinib in Newly Diagnosed Ph-positive Acute Leukemia and CML-AP/BP Patients

Who this might be right for
Philadelphia ChromosomeAcute Myeloid LeukemiaAcute Lymphoblastic Leukemia+2 more
The First Affiliated Hospital of Soochow University 20
Testing effectiveness (Phase 2)Study completedNCT04827745
What this trial is testing

Blinatumomab for Treatment of R/R or MRD-positive CD19-Positive MPAL

Who this might be right for
Mixed Phenotype Acute Leukemia (MPAL)Measurable Residual Disease (MRD)
University of Maryland, Baltimore 2
Not applicableStudy completedNCT05270395
What this trial is testing

Piloting 'mPal,' a Multilevel Strategy for Palliative Care Implementation

Who this might be right for
Lung Cancer
Laurie McLouth 75
Post-approval studies (Phase 4)Looking for participantsNCT06289673
What this trial is testing

Identification of Necessary Information for Treatment Induction in Newly Diagnosed Acute Lymphoblastic Leukemia/Lymphoma

Who this might be right for
Acute Lymphoblastic LeukemiaLymphoblastic LymphomaMixed Phenotype Acute Leukemia
St. Jude Children's Research Hospital 850
Not applicableNot Yet RecruitingNCT06991920
What this trial is testing

Immune-targeted Combination With Chemotherapy for Acute Leukemia of Ambiguous Lineage

Who this might be right for
Adult ALLMPAL
Institute of Hematology & Blood Diseases Hospital, China 50
Very early researchNot Yet RecruitingNCT06876701
What this trial is testing

The Treatment of Newly Diagnosed CD19+Mixed Phenotype Acute Leukemia in Adults

Who this might be right for
Acute Leukemia
Ruijin Hospital 10
Testing effectiveness (Phase 2)Looking for participantsNCT07222579
What this trial is testing

Subcutaneous Blinatumomab for Treatment of Adult Patients With CD19-Positive Mixed Phenotype Acute Leukemia (MPAL)

Who this might be right for
CD19 PositiveMixed Phenotype Acute Leukemia (MPAL)
West Virginia University 78
Early research (Phase 1)Active Not RecruitingNCT03843528
What this trial is testing

Vorinostat Dose-escalation After Allogeneic Hematopoietic Cell Transplantation

Who this might be right for
Acute Myeloid LeukemiaMyelodysplastic SyndromesMixed Phenotype Acute Leukemia+1 more
Johns Hopkins All Children's Hospital 15
Early research (Phase 1)Active Not RecruitingNCT06325748
What this trial is testing

SENTI-202: Off-the-shelf Logic Gated CAR NK Cell Therapy in Adults With CD33 and/or FLT3 Blood Cancers Including AML/MDS

Who this might be right for
AML/MDSCD33 Expressing Hematological MalignanciesFLT3 Expressing Hematological Malignancies
Senti Biosciences 21
Early research (Phase 1)WithdrawnNCT07498465
What this trial is testing

Find the Highest Dose of SNDX-5613 (Revumenib) as a Treatment Option After Hematopoietic Stem Cell Transplant in Children With Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, and Mixed Phenotype Acute Leukemia

Who this might be right for
Acute Lymphoblastic LeukemiaAcute Myeloid LeukemiaChildhood Acute Lymphoblastic Leukemia+3 more
Children's Oncology Group
Early research (Phase 1)Ended earlyNCT01887587
What this trial is testing

Vincristine, Doxorubicin, And Dexamethasone + Ixazomib in Acute Lymphoblastic Leukemia (ALL), Lymphoblastic Lymphoma Or Mixed Phenotype Acute Leukemia

Who this might be right for
Relapsed or Refractory Acute Lymphoblastic LeukemiaRelapsed or Refractory Lymphoblastic LymphomaMixed Phenotype Acute Leukemia
Ehab L Atallah 5
Early research (Phase 1)Active Not RecruitingNCT02879695
What this trial is testing

Blinatumomab and Nivolumab With or Without Ipilimumab in Treating Patients With Poor-Risk Relapsed or Refractory CD19+ Precursor B-Lymphoblastic Leukemia

Who this might be right for
Recurrent B Acute Lymphoblastic LeukemiaRecurrent Mixed Phenotype Acute LeukemiaRefractory B Acute Lymphoblastic Leukemia+1 more
National Cancer Institute (NCI) 28
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