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Results for “MPN (Myeloproliferative Neoplasms)”

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Showing 20 of 0 results

Early research (Phase 1)Study completedNCT03895112
What this trial is testing

MPN-RC 118 AVID200 in Myelofibrosis

Who this might be right for
Primary MyelofibrosisPost-essential Thrombocythemia MyelofibrosisPost-polycythemia Vera Myelofibrosis+2 more
John Mascarenhas 21
Early research (Phase 1)Ended earlyNCT02663518
What this trial is testing

A Trial of PF-07901800 (TTI-621) for Patients With Hematologic Malignancies and Selected Solid Tumors

Who this might be right for
Hematologic MalignanciesSolid Tumor
Pfizer 249
Testing effectiveness (Phase 2)Ended earlyNCT02393248
What this trial is testing

Open-Label, Dose-Escalation Study of Pemigatinib in Subjects With Advanced Malignancies - (FIGHT-101)

Who this might be right for
Lung CancerSolid TumorGastric Cancer+8 more
Incyte Corporation 201
Testing effectiveness (Phase 2)Ended earlyNCT02431260
What this trial is testing

An Open-Label, Dose-Escalation Study of INCB054329 in Patients With Advanced Malignancies

Who this might be right for
Solid Tumors and Hematologic Malignancy
Incyte Corporation 69
Large-scale testing (Phase 3)Looking for participantsNCT04064060
What this trial is testing

Evaluate Long-term Safety in Participants Who Have Participated in Other Luspatercept (ACE-536) Clinical Trials

Who this might be right for
Myelodysplastic Syndromes (MDS)Beta-thalassemiaMyeloproliferative Neoplasm(MPN)-Associated Myelofibrosis
Celgene 665
Testing effectiveness (Phase 2)Ended earlyNCT05005182
What this trial is testing

Luspatercept With or Without Hydroxyurea for the Treatment of Myelodysplastic/Myeloproliferative Neoplasms With Ring Sideroblasts and Thrombocytosis or Unclassifiable With Ring Sideroblasts

Who this might be right for
Myelodysplastic/Myeloproliferative Neoplasm With Ring Sideroblasts and Thrombocytosis, Not Otherwise SpecifiedMyelodysplastic/Myeloproliferative Neoplasm, Not Otherwise Specified
Mayo Clinic 3
Large-scale testing (Phase 3)Ended earlyNCT02055781
What this trial is testing

Pacritinib Versus Best Available Therapy to Treat Patients With Myelofibrosis and Thrombocytopenia

Who this might be right for
Primary MyelofibrosisPost-polycythemia Vera MyelofibrosisPost-essential Thrombocythemia Myelofibrosis
CTI BioPharma 311
Testing effectiveness (Phase 2)Ended earlyNCT02718300
What this trial is testing

INCB050465 in Combination With Ruxolitinib in Subjects With Myelofibrosis

Who this might be right for
MPN (Myeloproliferative Neoplasms)
Incyte Corporation 74
Large-scale testing (Phase 3)Active Not RecruitingNCT04285086
What this trial is testing

Ropeginterferon Alfa-2b (P1101) vs. Anagrelide in Essential Thrombocythemia Patients With Hydroxyurea Resistance or Intolerance

Who this might be right for
Essential Thrombocythemia
PharmaEssentia 174
Not applicableNot Yet RecruitingNCT07108023
What this trial is testing

Hematological Disorders in EHPVO Patients

Who this might be right for
Extrahepatic Portal Vein Obstruction (EHPVO)ThrombophiliaMyeloproliferative Neoplasms (MPN)+5 more
Rahab Nady 115
Testing effectiveness (Phase 2)Study completedNCT02807272
What this trial is testing

Tipifarnib in Subjects With Chronic Myelomonocytic Leukemia, Other MDS/MPN, and Acute Myeloid Leukemia

Who this might be right for
Leukemia, Myelomonocytic, Chronic
Kura Oncology, Inc. 44
Large-scale testing (Phase 3)Ended earlyNCT04551053
What this trial is testing

To Evaluate Efficacy and Safety of Parsaclisib and Ruxolitinib in Participants With Myelofibrosis Who Have Suboptimal Response to Ruxolitinib (LIMBER-304)

Who this might be right for
MyelofibrosisPrimary MyelofibrosisPost Essential Thrombocythemia Myelofibrosis+1 more
Incyte Corporation 177
Testing effectiveness (Phase 2)Study completedNCT04243122
What this trial is testing

Assessing Feasibility of Thromboprophylaxis With Apixaban in JAK2-positive Myeloproliferative Neoplasm Patients

Who this might be right for
Myeloproliferative Neoplasm (MPN)Essential Thrombocythemia (ET)JAK2 Mutation+3 more
Ottawa Hospital Research Institute 44
Early research (Phase 1)Active Not RecruitingNCT04041050
What this trial is testing

A Study Evaluating Safety and Tolerability, and Pharmacokinetics of Navitoclax Monotherapy and in Combination With Ruxolitinib in Participants With Myeloproliferative Neoplasm

Who this might be right for
Myeloproliferative Neoplasm
AbbVie 85
Large-scale testing (Phase 3)Active Not RecruitingNCT06468033
What this trial is testing

P1101 in Treating Patients With Early PMF or Overt PMF at Low or Intermediate-1 Risk

Who this might be right for
Primary MyelofibrosisMyeloproliferative Neoplasm
PharmaEssentia 160
Early research (Phase 1)Study completedNCT01393509
What this trial is testing

The First-in-human Phase I Trial of PU-H71 in Patients With Advanced Malignancies

Who this might be right for
Metastatic Solid TumorLymphomaMyeloproliferative Neoplasms (MPN)
Memorial Sloan Kettering Cancer Center 47
Testing effectiveness (Phase 2)Ended earlyNCT03287245
What this trial is testing

Evaluate the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of Idasanutlin Monotherapy in Participants With Hydroxyurea-Resistant/Intolerant Polycythemia Vera

Who this might be right for
Polycythemia Vera
Hoffmann-La Roche 27
Not applicableNot Yet RecruitingNCT06615414
What this trial is testing

Cardiovascular Manifestations in Ph-negative MPN

Who this might be right for
Philadelphia Negative Myeloproliferative Neoplasms
Assiut University 80
Testing effectiveness (Phase 2)Ended earlyNCT02711137
What this trial is testing

Open-Label Safety and Tolerability Study of INCB057643 in Subjects With Advanced Malignancies

Who this might be right for
Solid Tumors
Incyte Corporation 137
Testing effectiveness (Phase 2)Study completedNCT02084563
What this trial is testing

Study of Molecular and Genetic Abnormalities in Patients With Myeloid Neoplasms

Who this might be right for
Acute Myeloid LeukemiaMyeloproliferative NeoplasmsMyelodysplastic Syndromes+1 more
Hospital Israelita Albert Einstein 455
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