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Results for “MPNST (Malignant Peripheral Nerve Sheath Tumor)”

112 trials

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Showing 20 of 112 results

Early research (Phase 1)Study completedNCT02211768
What this trial is testing

Transformation of Plexiform Neurofibromas to Malignant Peripheral Nerve Sheath Tumors in Neurofibromatosis Type 1

Who this might be right for
NeurofibromatosisMPNST
National Cancer Institute (NCI) 10
Testing effectiveness (Phase 2)Looking for participantsNCT06849986
What this trial is testing

IO Combined With AI as First-line Treatment for Patients With Soft Tissue Sarcoma(TAIS)

Who this might be right for
Soft Tissue SarcomasAngiosarcomaFibrosarcoma+4 more
Fudan University 45
Early research (Phase 1)Active Not RecruitingNCT03618381
What this trial is testing

EGFR806 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults

Who this might be right for
Pediatric Solid TumorGerm Cell TumorRetinoblastoma+13 more
Seattle Children's Hospital 44
Not applicableStudy completedNCT00003793
What this trial is testing

Genetic Study of Children With Soft Tissue Sarcoma or Rhabdomyosarcoma

Who this might be right for
LeukemiaMyelodysplastic SyndromesSarcoma
Children's Oncology Group 294
Early research (Phase 1)Active Not RecruitingNCT04483778
What this trial is testing

B7H3 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults

Who this might be right for
Pediatric Solid TumorGerm Cell TumorRetinoblastoma+14 more
Seattle Children's Hospital 68
Not applicableUnknownNCT01218152
What this trial is testing

Microarray CGH Analysis of Circulating Tumoral Plasma DNA in NF1 Patients With MPNSTs

Who this might be right for
Neurofibromatosis Type 1
KU Leuven 20
Early research (Phase 1)Looking for participantsNCT04222413
What this trial is testing

Metarrestin (ML-246) in Subjects With Metastatic Solid Tumors

Who this might be right for
Advanced Solid TumorsMetastatic Pancreatic CancerPediatric Solid Tumor+3 more
National Cancer Institute (NCI) 116
Large-scale testing (Phase 3)Study completedNCT00003052
What this trial is testing

Combination Chemotherapy With or Without Hyperthermia Therapy in Treating Patients With Soft Tissue Sarcoma

Who this might be right for
Sarcoma
European Organisation for Research and Treatment of Cancer - EORTC 340
Very early researchLooking for participantsNCT06693284
What this trial is testing

A Window of Opportunity Trial of Mirdametinib Plus Vorinostat for NF1 Associated, H3K27 Trimethylation Deficient Malignant Peripheral Nerve Sheath Tumor [MPNST]

Who this might be right for
Primary Malignant Peripheral Nerve Sheath Tumors
University of Minnesota 8
Not applicableWithdrawnNCT00334984
What this trial is testing

Glutamine in Preventing Oral Mucositis in Patients Receiving Chemotherapy for Sarcoma

Who this might be right for
Childhood Malignant Fibrous Histiocytoma of BoneSarcoma
Children's Oncology Group
Early research (Phase 1)Looking for participantsNCT05245500
What this trial is testing

Phase 1 Study of MRTX1719 in Solid Tumors With MTAP Deletion

Who this might be right for
MesotheliomaNon Small Cell Lung CancerMalignant Peripheral Nerve Sheath Tumors+3 more
Bristol-Myers Squibb 336
Testing effectiveness (Phase 2)UnknownNCT01883518
What this trial is testing

Autologous Dendritic Cell Vaccine in Patients With Soft Tissue Sarcoma

Who this might be right for
SarcomaNeoplasms, Connective and Soft Tissue
N.N. Petrov National Medical Research Center of Oncology 48
Testing effectiveness (Phase 2)Active Not RecruitingNCT04917042
What this trial is testing

Tazemetostat in Malignant Peripheral Nerve Sheath Tumors

Who this might be right for
Peripheral Nerve Sheath Tumor
University of Florida 10
Large-scale testing (Phase 3)Study completedNCT00346164
What this trial is testing

Observation, Radiation Therapy, Combination Chemotherapy, and/or Surgery in Treating Young Patients With Soft Tissue Sarcoma

Who this might be right for
Adult Alveolar Soft-part SarcomaAdult AngiosarcomaAdult Epithelioid Sarcoma+26 more
Children's Oncology Group 588
Testing effectiveness (Phase 2)Study completedNCT00006357
What this trial is testing

STI571 in Treating Patients With Recurrent or Refractory Soft Tissue Sarcoma

Who this might be right for
Endometrial CancerGastrointestinal Stromal TumorOvarian Cancer+2 more
European Organisation for Research and Treatment of Cancer - EORTC 91
Testing effectiveness (Phase 2)Active Not RecruitingNCT03872427
What this trial is testing

Testing Whether Cancers With Specific Mutations Respond Better to Glutaminase Inhibitor, Telaglenastat Hydrochloride, Anti-Cancer Treatment, BeGIN Study

Who this might be right for
Advanced Malignant Solid NeoplasmMetastatic Malignant Solid NeoplasmNF1 Mutation Positive Malignant Peripheral Nerve Sheath Tumor+1 more
National Cancer Institute (NCI) 54
Testing effectiveness (Phase 2)Study completedNCT00154388
What this trial is testing

Phase II Study of Imatinib Mesylate in Patients With Life Threatening Malignant Rare Diseases

Who this might be right for
Life Threatening Diseases
Novartis Pharmaceuticals 185
Large-scale testing (Phase 3)UnknownNCT00334854
What this trial is testing

Ifosfamide and Doxorubicin, Radiation Therapy, and/or Surgery in Treating Young Patients With Localized Soft Tissue Sarcoma

Who this might be right for
Childhood Malignant Fibrous Histiocytoma of BoneSarcoma
European Paediatric Soft Tissue Sarcoma Study Group 250
Large-scale testing (Phase 3)Study completedNCT00091351
What this trial is testing

Surgery With or Without Radiation Therapy in Treating Patients With Primary Soft Tissue Sarcoma of the Retroperitoneum or Pelvis

Who this might be right for
Sarcoma
Alliance for Clinical Trials in Oncology 370
Testing effectiveness (Phase 2)Study completedNCT03719430
What this trial is testing

APX005M and Doxorubicin in Advanced Sarcoma

Who this might be right for
Soft Tissue Sarcoma
Alexander Z. Wei, MD 27
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