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Results for “MSI-H/dMMR Colorectal Cancer”

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Showing 20 of 0 results

Testing effectiveness (Phase 2)UnknownNCT05371197
What this trial is testing

Envafolimab as Neoadjuvant Immuntherapy in Resectable Local Advanced dMMR/MSI-H Colorectal Cancer

Who this might be right for
Colorectal CancerMismatch Repair-deficient (dMMR)Microsatellite Instability-high (MSI-H)+1 more
Third Affiliated Hospital, Sun Yat-Sen University 26
Testing effectiveness (Phase 2)Active Not RecruitingNCT04751370
What this trial is testing

Testing Nivolumab and Ipilimumab With Short-Course Radiation in Locally Advanced Rectal Cancer

Who this might be right for
Locally Advanced Rectal AdenocarcinomaStage II Rectal Cancer AJCC v8Stage III Rectal Cancer AJCC v8
National Cancer Institute (NCI) 31
Testing effectiveness (Phase 2)Looking for participantsNCT06698757
What this trial is testing

Different Cycles of Preoperative Neoadjuvant Sintilimab in Mismatch-repair Deficient/microsatellite Instability-high, Locally Advanced Colorectal Cancer

Who this might be right for
Colorectal Cancer
Yugui Lian 96
Testing effectiveness (Phase 2)Looking for participantsNCT06205836
What this trial is testing

Cemiplimab With or Without Fianlimab to Treat Older Patients With Localized or Locally Advanced MSI-H Colorectal Cancer

Who this might be right for
Colorectal Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 44
Early research (Phase 1)Study completedNCT02635672
What this trial is testing

Phase I Dose Escalation Study for VIP152 in Patients With Advanced Cancer

Who this might be right for
Neoplasms
Vincerx Pharma, Inc. 110
Early research (Phase 1)Active Not RecruitingNCT05838768
What this trial is testing

Study of HRO761 Alone or in Combination in Cancer Patients With Specific DNA Alterations Called Microsatellite Instability or Mismatch Repair Deficiency.

Who this might be right for
MSIhi or dMMR Advanced Unresectable or Metastatic Solid Tumors, Including Colorectal Cancers
Novartis Pharmaceuticals 123
Testing effectiveness (Phase 2)UnknownNCT05913570
What this trial is testing

Cadonilimab as Neoadjuvant Therapy in Resectable Stage II-III MSI-H/dMMR Colorectal Cancer

Who this might be right for
Colorectal CancerMismatch Repair-deficient (dMMR)Microsatellite Instability-high (MSI-H)+1 more
LiuYing 22
Large-scale testing (Phase 3)Looking for participantsNCT05236972
What this trial is testing

PACE: PD-1 Antibody For dMMR/MSI-H Stage III Colorectal Cancer

Who this might be right for
Colorectal Carcinoma
Sun Yat-sen University 323
Testing effectiveness (Phase 2)Study completedNCT02060188
What this trial is testing

Nivolumab Alone or Nivolumab Combination Therapy in Colon Cancer That Has Come Back or Has Spread

Who this might be right for
Microsatellite Unstable Colorectal CancerMicrosatellite Stable Colorectal CancerMismatch Repair Proficient Colorectal Cancer+1 more
Bristol-Myers Squibb 385
Large-scale testing (Phase 3)Not Yet RecruitingNCT07740720
What this trial is testing

The Duration of Dostarlimab in Untreated Mismatch Repair Deficient (dMMR)/ Microsatellite Instability-high (MSI-H) Locally Advanced Rectal Cancer

Who this might be right for
Neoplasms, Rectal
GlaxoSmithKline 90
Not applicableNot Yet RecruitingNCT07656740
What this trial is testing

Non-Operative Management and Following Immunotherapy for Colorectal Cancer and Other GI Cancers

Who this might be right for
Gastrointestinal CancerColorectal (Colon or Rectal) CancerStomach (Gastric) Cancer
Peking University Cancer Hospital & Institute 50
Not applicableStudy completedNCT04482608
What this trial is testing

The mCRC Patients With pMMR/MSS or dMMR/MSI-H Status Received Palliative Chemotherapy Efficacy and Survival

Who this might be right for
Colorectal Cancer MetastaticMismatch Repair DeficiencyMicrosatellite Instability High
Sun Yat-sen University 671
Testing effectiveness (Phase 2)UnknownNCT04636008
What this trial is testing

Sintilimab Plus Hypofractionated Radiotherapy for MSI-H/dMMR Rectal Cancer

Who this might be right for
Anti-PD-1 AntibodyRadiotherapyRectal Cancer+2 more
West China Hospital 20
Large-scale testing (Phase 3)Active Not RecruitingNCT05652894
What this trial is testing

HX008 Compared to Chemotherapy in the First-Line Treatment of Subjects With MSI-H/dMMR Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
Taizhou Hanzhong biomedical co. LTD 190
Large-scale testing (Phase 3)Study completedNCT02563002
What this trial is testing

Study of Pembrolizumab (MK-3475) vs Standard Therapy in Participants With Microsatellite Instability-High (MSI-H) or Mismatch Repair Deficient (dMMR) Stage IV Colorectal Carcinoma (MK-3475-177/KEYNOTE-177)

Who this might be right for
Colorectal Carcinoma
Merck Sharp & Dohme LLC 307
Testing effectiveness (Phase 2)Active Not RecruitingNCT04802876
What this trial is testing

Efficacy of Tislelizumab and Spartalizumab Across Multiple Cancer-types in Patients with PD1-high MRNA Expressing Tumors

Who this might be right for
MSI-H Colorectal CancerMelanomaAnal Carcinoma+28 more
SOLTI Breast Cancer Research Group 184
Early research (Phase 1)Ended earlyNCT04244552
What this trial is testing

A Phase 1b Trial of ATRC-101 in Adults With Advanced Solid Malignancies

Who this might be right for
Breast CancerColorectal CancerOvarian Cancer+13 more
Atreca, Inc. 87
Testing effectiveness (Phase 2)Active Not RecruitingNCT06640049
What this trial is testing

Dostarlimab in Participants With Untreated Locally Advanced Rectal Cancer in China

Who this might be right for
Neoplasms, Rectal
GlaxoSmithKline 23
Testing effectiveness (Phase 2)UnknownNCT05429866
What this trial is testing

Immunological Variables Associated to ICI Toxicity in Cancer Patients

Who this might be right for
Breast CancerMelanomaNon Small Cell Lung Cancer+10 more
Jules Bordet Institute 441
Not applicableLooking for participantsNCT04643041
What this trial is testing

Watch and Wait in PD-1 Monoclonal Antibody Treated dMMR/MSI-H Distal Rectal Cancer

Who this might be right for
Rectal Cancer
Sixth Affiliated Hospital, Sun Yat-sen University 47
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