Testing effectiveness (Phase 2)Looking for participantsNCT03667170What this trial is testingKN035 for dMMR/MSI-H Advanced Solid TumorsWho this might be right forSolid Tumor 3D Medicines (Sichuan) Co., Ltd. 200
Early research (Phase 1)Study completedNCT04242199What this trial is testingSafety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099280 in Participants With Advanced Solid TumorsWho this might be right forAdvanced Solid TumorMSI-H/dMMR TumorsCutaneous Squamous Cell Carcinoma+9 more Incyte Corporation 182
Testing effectiveness (Phase 2)WithdrawnNCT04001101What this trial is testingAnti-PD-1 +/- RT for MSI-H Solid TumorsWho this might be right forMicrosatellite Instability HighMismatch Repair DeficiencyColorectal Cancer University of Colorado, Denver
Testing effectiveness (Phase 2)Looking for participantsNCT04114136What this trial is testingAnti-PD-1 mAb Plus Metabolic Modulator in Solid Tumor MalignanciesWho this might be right forMelanomaNSCLCHepatocellular Carcinoma+5 more Dan Zandberg 72
Testing effectiveness (Phase 2)Active Not RecruitingNCT05879822What this trial is testingEvaluate INCB099280 in Participants With Select Solid Tumors Who Are Immune Checkpoint Inhibitor NaiveWho this might be right forAdvanced Solid Tumor Incyte Corporation 73
Testing effectiveness (Phase 2)Looking for participantsNCT02332668What this trial is testingPembrolizumab (MK-3475) in Pediatric Participants With an Advanced Solid Tumor or Lymphoma (MK-3475-051/KEYNOTE-051)Who this might be right forMelanomaLymphomaSolid Tumor+2 more Merck Sharp & Dohme LLC 370
Testing effectiveness (Phase 2)WithdrawnNCT06331598What this trial is testingAdjuvant Atezolizumab or Atezolizumab Plus Tiragolumab in Solid Tumors with Resectable Disease with Intermediate-High Risk of Recurrence and High Tumor Mutational Burden (TMB-H) or Microsatellite Instability (MSI-H)Who this might be right forSolid Tumors Hoffmann-La Roche
Testing effectiveness (Phase 2)UnknownNCT03475953What this trial is testingA Phase I/II Study of Regorafenib Plus Avelumab in Solid TumorsWho this might be right forColorectal Cancer Not MSI-H or MMR-deficientGISTOesophageal or Gastric Carcinoma+12 more Institut Bergonié 747
Early research (Phase 1)Ended earlyNCT04272034What this trial is testingSafety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099318 in Participants With Advanced Solid TumorsWho this might be right forAdvanced Solid TumorsMSI-H/dMMR TumorsCutaneous Squamous Cell Carcinoma+15 more Incyte Corporation 105
Not applicableUnknownNCT06004713What this trial is testingRegistry Study in MSI/dMMR Solid TumorsWho this might be right forDMMR CancerMSI-HSolid Tumor Peking University Cancer Hospital & Institute 190
Testing effectiveness (Phase 2)Ended earlyNCT05714553What this trial is testingNUC-3373 in Combination With Other Agents in Patients With Advanced Solid TumoursWho this might be right forAdvanced CancerAdvanced Solid TumorNeoplasm Malignant+14 more NuCana plc 19
Early research (Phase 1)Ended earlyNCT04458259What this trial is testingStudy of PF-07265807 in Participants With Metastatic Solid Tumors.Who this might be right forNeoplasm Metastasis Pfizer 88
Early research (Phase 1)Looking for participantsNCT06974110What this trial is testingStudy of Orally Administered MOMA-341 in Participants With Advanced or Metastatic Solid TumorsWho this might be right forAdvanced Solid TumorMetastatic Solid TumorEndometrial Cancer+4 more MOMA Therapeutics 132
Testing effectiveness (Phase 2)Looking for participantsNCT06898450What this trial is testingAssess the Safety, Tolerability, and Efficacy of NDI-219216 in Patients With Advanced Solid Tumors.Who this might be right forAdvanced Solid Tumors CancerMSI-H Cancer Nimbus Wadjet, Inc. 134
Testing effectiveness (Phase 2)Active Not RecruitingNCT05199272What this trial is testingA Phase 1/2a Study of 23ME-00610 in Patients With Advanced Solid MalignanciesWho this might be right forSolid TumorClear Cell Renal Cell CarcinomaEpithelial Ovarian Cancer+6 more 23andMe, Inc. 141
Early research (Phase 1)Study completedNCT03236935What this trial is testingPhase Ib of L-NMMA and PembrolizumabWho this might be right forNon-Small Cell Lung CancerMalignant MelanomaHead and Neck Squamous Cell Carcinoma+3 more The Methodist Hospital Research Institute 12
Testing effectiveness (Phase 2)Looking for participantsNCT03941574What this trial is testingA Clinical Study to Evaluate HLX10 Monotherapy for the Treatment of MSI-H or dMMR Solid Tumors That Failed to Respond to Standard TherapyWho this might be right forMSI-H Solid Malignant Tumor Shanghai Henlius Biotech 108
Testing effectiveness (Phase 2)Looking for participantsNCT06580574What this trial is testingImmune Checkpoint Inhibitors for Organ Preservation in Non-metastatic dMMR/MSI-H Gastric or Colon CancersWho this might be right forGastric CancerColon CancerMSI-H+1 more Peking University 34
Testing effectiveness (Phase 2)Ended earlyNCT04547101What this trial is testingAK104 in Subjects With Locally Advanced Unresectable or Metastatic MSI-H/dMMR Solid TumorsWho this might be right forMSI-H/dMMR Solid Tumor Akeso 6
Testing effectiveness (Phase 2)Study completedNCT03436563What this trial is testingM7824 in Patients With Metastatic Colorectal Cancer or With Advanced Solid Tumors With Microsatellite InstabilityWho this might be right forColon AdenocarcinomaHigh-Frequency Microsatellite InstabilityMetastatic Malignant Solid Neoplasm+8 more M.D. Anderson Cancer Center 4