Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “MSS/pMMR”

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 0 results

Not applicableNot Yet RecruitingNCT06823323
What this trial is testing

The Study on the Efficacy and Safety of Lactobacillus Johnsonii in Combination with CapeOX and Pembrolizumab for the Treatment of MSS/pMMR Metastatic Colorectal Cancer.

Who this might be right for
Metastatic Colorectal Cancer (CRC)
Second Affiliated Hospital, Zhejiang University, School of Medicine 150
Testing effectiveness (Phase 2)Looking for participantsNCT07544784
What this trial is testing

AK104 Plus Radiotherapy Combined With Standard Therapy Versus Standard Therapy as First-Line Treatment for pMMR/MSS CRLM (APSOC)

Who this might be right for
Colorectal Cancer Liver Metastases (CRLM)
Fudan University 73
Testing effectiveness (Phase 2)Looking for participantsNCT07468630
What this trial is testing

Tolecizumab Plus Chemoimmunotherapy for pMMR/MSS Locally Advanced Colon Adenocarcinoma

Who this might be right for
Colon Adenocarcinoma
Daping Hospital and the Research Institute of Surgery of the Third Military Medical University 106
Testing effectiveness (Phase 2)Looking for participantsNCT07279077
What this trial is testing

Node-Sparing Low-Dose Radiotherapy Concurrent With Chemotherapy and PD-1 Inhibitor in pMMR/MSS High-Risk Locally Advanced Colon Cancer: A Prospective, Single-Arm, Phase II Trial

Who this might be right for
Colon CancerNeoadjuvant TherapiesImmune Checkpoint Therapy+1 more
Sixth Affiliated Hospital, Sun Yat-sen University 38
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07007767
What this trial is testing

Exploring Sintilimab + Bevacizumab + Decitabine for Advanced pMMR/MSS Colorectal Cancer (After 2+ Prior Therapies）

Who this might be right for
Colorectal Cancer Metastatic
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 32
Testing effectiveness (Phase 2)Study completedNCT04126733
What this trial is testing

Study on the Effectiveness and Safety of the Combination of the Two Drugs Regorafenib and Nivolumab in Patients With Colorectal Cancer (Cancer of the Colon or Rectum Classified as Proficient Mismatch Repair and Microsatellite Stable)

Who this might be right for
Colorectal Cancer
Bayer 70
Testing effectiveness (Phase 2)Looking for participantsNCT07458529
What this trial is testing

Neoadjuvant Chemoradiotherapy Plus Tislelizumab With or Without Probio-M9 in pMMR/MSS Locally Advanced Rectal Cancer

Who this might be right for
Rectal Cancer, AdenocarcinomaNeoadjuvant TherapyImmunotherapy+3 more
Seventh Medical Center of PLA General Hospital 50
Large-scale testing (Phase 3)Looking for participantsNCT06280495
What this trial is testing

Neoadjuvant Serplulimab & Bevacizumab With FOLFOX vs. FOLFOX Alone in RAS/BRAF WT, pMMR/MSS CRC Patients

Who this might be right for
Colorectal CancerLiver Metastases
Sun Yat-sen University 156
Large-scale testing (Phase 3)Not Yet RecruitingNCT07595276
What this trial is testing

Comparing Efficacy and Safety of Enlituo® Versus Erbitux® Plus FOLFOX in Locally Advanced/Metastatic Colorectal Cancer With RAS/BRAF Wild-type and MSS/pMMR Status.

Who this might be right for
Colorectal Cancer
Taizhou Mabtech Pharmaceutical Co.,Ltd 608
Testing effectiveness (Phase 2)Active Not RecruitingNCT06933251
What this trial is testing

PCSK9 Inhibitor and PD-1 Inhibitor Combined With Neoadjuvant Chemoradiotherapy for pMMR/MSS Locally Advanced Rectal Cancer

Who this might be right for
Locally Advanced Rectal Cancer (LARC)
Guangdong Provincial People's Hospital 30
Testing effectiveness (Phase 2)Looking for participantsNCT06685276
What this trial is testing

Safety and Efficacy of Fruquintinib Plus Chidamide and Sintilimab in the Third and Later Line Treatment of MSS/pMMR Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer Metastatic
Dai, Guanghai 46
Testing effectiveness (Phase 2)Active Not RecruitingNCT05846867
What this trial is testing

A Phase Ib/II Clinical Study on AK112 Combined or Not Combined With AK119 in pMMR/MSS Colorectal Cancer

Who this might be right for
Colorectal Cancer
Akeso 170
Not applicableNot Yet RecruitingNCT06504875
What this trial is testing

Application of PD-1 Monoclonal Antibody in Combination With IL-2 and CapeOX in Organ Preservation Therapy for Ultra-Low Localized Advanced Rectal Cancer

Who this might be right for
Rectal Cancer
The First Affiliated Hospital with Nanjing Medical University 23
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06218888
What this trial is testing

A Phase II Clinical Study of the Efficacy and Safety of Tislelizumab Combined With Fruquintinib and Chidamide in the Treatment of Unresectable or Advanced Microsatellite Stabilized (MSS/pMMR) Colorectal Cancer With Liver Metastases

Who this might be right for
Colo-rectal Cancer
Fujian Cancer Hospital 17
Early research (Phase 1)Looking for participantsNCT06513624
What this trial is testing

ETC-159 In Combination With Pembrolizumab In Advanced MSS/pMMR Ovarian Cancers

Who this might be right for
With MSS/pMMR Advanced, Platinum-resistant Ovarian Cancer
National University Hospital, Singapore 16
Testing effectiveness (Phase 2)UnknownNCT04030260
What this trial is testing

Regorafenib and PD-1 Antibody in Combination With Radiotherapy for pMMR/MSS Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer MetastaticMSS
Sun Yat-sen University 28
Not applicableNot Yet RecruitingNCT06504901
What this trial is testing

Evaluation of Efficacy and Safety of PD-1 Monoclonal Antibody in Combination With rhG-CSF, IL-2, and CapeOX in Initially Resectable Synchronous Colorectal Liver Metastases

Who this might be right for
Colorectal Cancer
The First Affiliated Hospital with Nanjing Medical University 30
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07651007
What this trial is testing

Short-course RT Followed by NALIRIFOX Plus Pucotenlimab as Neoadjuvant Therapy for High-risk Locally Advanced Rectal Cancer With MSS/pMMR

Who this might be right for
Advanced Rectal Cancer
Wang Xin 29
Testing effectiveness (Phase 2)Looking for participantsNCT07079631
What this trial is testing

A Clinical Study to Test if an Investigational Treatment Called BNT314 When Used in Combination With Another Investigational Treatment Pumitamig (BNT327) and Chemotherapy, is Beneficial and Safe for Patients With Advanced Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
BioNTech SE 482
Testing effectiveness (Phase 2)Looking for participantsNCT07527026
What this trial is testing

A Single-arm Phase II Clinical Study of Camrelizumab Combined With Long-course Chemoradiotherapy for Total Neoadjuvant Therapy in Locally Advanced Low pMMR/MSS Rectal Cancer

Who this might be right for
Locally Advanced Rectal Cancer
Chinese PLA General Hospital 44
Next Page