Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “MSS Metastatic Colorectal Cancer”

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 0 results

Large-scale testing (Phase 3)Ended earlyNCT05328908
What this trial is testing

Nivolumab-relatlimab Fixed-dose Combination Versus Regorafenib or TAS-102 in Participants With Later-lines of Metastatic Colorectal Cancer

Who this might be right for
Colorectal Neoplasms
Bristol-Myers Squibb 769
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07021950
What this trial is testing

AK112 Plus FOLFIRI Versus Bevacizumab Plus FOLFIRI as Second-line Treatment of MSS/pMMR Metastatic Colorectal Cancer

Who this might be right for
Colorectal CancerIvonescimab
Sun Yat-sen University 130
Early research (Phase 1)Ended earlyNCT04060342
What this trial is testing

GB1275 Monotherapy and in Combination With an Anti-PD1 Antibody in Patients With Specified Advanced Solid Tumors or in Combination With Standard of Care in Patients With Metastatic Pancreatic Adenocarcinoma

Who this might be right for
Pancreatic AdenocarcinomaEsophageal AdenocarcinomaEsophageal Squamous Cell Carcinoma+11 more
GB006, Inc., a wholly owned subsidiary of Gossamer Bio, Inc. 61
Testing effectiveness (Phase 2)Looking for participantsNCT07446322
What this trial is testing

FOLFIRI and Bevacizumab With or Without Pelareorep for Second-Line Treatment of Metastatic RAS-Mutated, Microsatellite-Stable Colorectal Cancer

Who this might be right for
Ras-mutated Metastatic Colorectal CancermCRCMSS Metastatic Colorectal Cancer
Oncolytics Biotech 60
Early research (Phase 1)Study completedNCT03005002
What this trial is testing

Durvalumab and Tremelimumab in Treating Patients With Microsatellite Stable Metastatic Colorectal Cancer to the Liver

Who this might be right for
Metastatic Carcinoma in the LiverMLH1 Gene MutationMSH6 Gene Mutation+4 more
City of Hope Medical Center 9
Testing effectiveness (Phase 2)Looking for participantsNCT06856837
What this trial is testing

- IKF/AIO-QUINTIS - Evaluating Fruquintinib in Combination With Tislelizumab in Microsatellite Stable / Proficient Mismatch Repair (MSS/pMMR) Metastatic Colorectal Cancer Without Active Liver Metastases

Who this might be right for
Metastatic Colorectal Cancer
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest 140
Testing effectiveness (Phase 2)Study completedNCT03631407
What this trial is testing

Safety and Efficacy of Vicriviroc (MK-7690) in Combination With Pembrolizumab (MK-3475) in Participants With Advanced/Metastatic Microsatellite Stable (MSS) Colorectal Cancer (CRC) (MK-7690-046)

Who this might be right for
Colorectal Neoplasms
Merck Sharp & Dohme LLC 41
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07007767
What this trial is testing

Exploring Sintilimab + Bevacizumab + Decitabine for Advanced pMMR/MSS Colorectal Cancer (After 2+ Prior Therapies）

Who this might be right for
Colorectal Cancer Metastatic
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 32
Large-scale testing (Phase 3)Not Yet RecruitingNCT06959693
What this trial is testing

A Clinical Study to Evaluate the Efficacy and Safety of Envafolimab Combined With Cetuxima-βand mFOLFOX6 in Patients With MSS, RAS/BRAF Wild-Type Metastatic Colorectal Cancer (mCRC)

Who this might be right for
Metastatic Colorectal Cancer (CRC)
Sun Yat-sen University 590
Testing effectiveness (Phase 2)UnknownNCT05551247
What this trial is testing

Envafolimab Combined With Endostatin in Recurrent or Metastatic MSS-type Colorectal Cancer

Who this might be right for
Colorectal Neoplasms
First Affiliated Hospital Xi'an Jiaotong University 30
Early research (Phase 1)Ended earlyNCT04108481
What this trial is testing

Immunotherapy With Y90-RadioEmbolization for Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer MetastaticColon CancerMetastatic Colorectal Cancer+7 more
University of Iowa 5
Testing effectiveness (Phase 2)Looking for participantsNCT06484153
What this trial is testing

Fruquintinib and Pirfenidone in Combination With Anti-PD-1 Antibody in Advanced or Metastatic pMMR/MSS Colorectal Carcinoma

Who this might be right for
To Evaluate the Efficacy of Fruquintinib and Pirfenidone in Combination With Anti-PD-1 Antibody in Colorectal CarcinomaTo Evaluate Whether Pirfenidone Can Reshape the Tumor Microenvironment in Colorectal CancerCombination of Fruquintinib and Anti-PD-1 Antibody Was Reported to Improve Patient Prognosis in Colorectal Cancer
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Testing effectiveness (Phase 2)UnknownNCT05160727
What this trial is testing

Radiotherapy Combined With Tislelizumab and Irinotecan in MSS/pMMR Recurrence and Metastatic Colorectal Cancer

Who this might be right for
Mismatch Repair-proficientColorectal Cancer MetastaticMicrosatellite Stable
Zhejiang Cancer Hospital 44
Testing effectiveness (Phase 2)Study completedNCT03271047
What this trial is testing

Study of Binimetinib + Nivolumab Plus or Minus Ipilimumab in Patients With Previously Treated Microsatellite-stable (MSS) Metastatic Colorectal Cancer With RAS Mutation

Who this might be right for
MSSRAS-mutant Colorectal Cancer
Pfizer 75
Testing effectiveness (Phase 2)UnknownNCT04659382
What this trial is testing

Study to Evaluate Efficacy and Safety of Selective Internal Radiation Therapy Plus Xelox, Bevacizumab and Atezolizumab (Immune Chekpoint Inhibitor) in Patients With Liver-dominant Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal CancerpMMRMSS+2 more
Federation Francophone de Cancerologie Digestive 52
Testing effectiveness (Phase 2)Looking for participantsNCT05954429
What this trial is testing

Explore the Third-line Treatment of Fruquintinib Combined With Serplulimab in Advanced Non-liver-limited Metastatic Colorectal Cancer: a Single-center, Phase 2 Study

Who this might be right for
Colorectal Cancer
Fudan University 50
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07656766
What this trial is testing

Sintilimab Plus Gossypol Acetate in Advanced Colorectal Cancer

Who this might be right for
Advanced Colorectal Cancer
Peking University People's Hospital 32
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06513221
What this trial is testing

A Prospective Study of MSS-type Metastatic Colorectal Cancer Receiving Multiple Lines of Standard Chemotherapy, Bevacizumab Combined With Adebrelimab

Who this might be right for
Metastatic Colorectal Cancer
Fudan University 100
Early research (Phase 1)Study completedNCT04362839
What this trial is testing

Regorafenib, Ipilimumab and Nivolumab for the Treatment of Chemotherapy Resistant Microsatellite Stable Metastatic Colorectal Cancer

Who this might be right for
Advanced Colon AdenocarcinomaMetastatic Colon AdenocarcinomaMetastatic Colorectal Adenocarcinoma+22 more
City of Hope Medical Center 39
Testing effectiveness (Phase 2)Ended earlyNCT05716295
What this trial is testing

A Dose Escalation/Expansion Study of MDK-703 in Patients With Advanced or Metastatic Solid Tumors

Who this might be right for
Advanced or Metastatic Solid Tumors
Medikine, Inc. 26
Next Page
25