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Results for “MTAP-deleted Solid Tumors”

21 trials

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Showing 20 of 21 results

Early research (Phase 1)Active Not RecruitingNCT04794699
What this trial is testing

Study of IDE397 in Participants With Solid Tumors Harboring MTAP Deletion

Who this might be right for
Solid Tumor
IDEAYA Biosciences 169
Early research (Phase 1)Not Yet RecruitingNCT07469982
What this trial is testing

A Phase I Study of SY-9453 in Patients With Advanced Solid Tumors

Who this might be right for
Advanced or Metastatic Solid Tumors With Homozygous MTAP Deletion
Shouyao Holdings (Beijing) Co. LTD 122
Testing effectiveness (Phase 2)Looking for participantsNCT06914128
What this trial is testing

A First-in-human Study to Learn How Safe BAY 3713372 is and How it Works in Participants With MTAP-deleted Solid Tumors

Who this might be right for
MTAP-deleted Solid Tumors
Bayer 370
Early research (Phase 1)Looking for participantsNCT06968572
What this trial is testing

Phase I Study of HSK41959 in Solid Tumors With MTAP Deletion

Who this might be right for
Advanced Solid Tumors
Haisco Pharmaceutical Group Co., Ltd. 245
Early research (Phase 1)Looking for participantsNCT05245500
What this trial is testing

Phase 1 Study of MRTX1719 in Solid Tumors With MTAP Deletion

Who this might be right for
MesotheliomaNon Small Cell Lung CancerMalignant Peripheral Nerve Sheath Tumors+3 more
Bristol-Myers Squibb 336
Not applicableStudy completedNCT03361358
What this trial is testing

Pre-Screening Study to Identify MTAP Loss in Advanced Solid Tumors or Lymphoma

Who this might be right for
Advanced Solid TumorsLymphoma
Agios Pharmaceuticals, Inc. 44
Early research (Phase 1)Active Not RecruitingNCT06568614
What this trial is testing

An Investigational Study of BG-89894 Tablets in Participants With Advanced Solid Tumors

Who this might be right for
Advanced or Metastatic MTAP-deleted Solid Tumors
BeOne Medicines 29
Early research (Phase 1)Looking for participantsNCT06414460
What this trial is testing

Study of ISM3412 in Participants With Locally Advanced/Metastatic Solid Tumors

Who this might be right for
Locally Advanced/Metastatic Solid Tumors
InSilico Medicine Hong Kong Limited 80
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07492680
What this trial is testing

BMS-986504 Monotherapy and in Combination With Other Agents in Participants With Advanced and/or Metastatic Solid Tumors With Homozygous MTAP Deletion (MountainTAP-5)

Who this might be right for
Solid Tumors
Bristol-Myers Squibb 260
Testing effectiveness (Phase 2)Looking for participantsNCT05732831
What this trial is testing

Safety and Tolerability of TNG462 in Patients With MTAP-deleted Solid Tumors

Who this might be right for
Locally Advanced Solid Tumor
Tango Therapeutics, Inc. 225
Testing effectiveness (Phase 2)Looking for participantsNCT06188702
What this trial is testing

S095035 as a Single Agent and in Combination in Adult Participants With Advanced or Metastatic Solid Tumors With Deletion of MTAP

Who this might be right for
MTAP-deleted Solid Tumors
Servier Bio-Innovation LLC 342
Early research (Phase 1)Looking for participantsNCT07277413
What this trial is testing

IDE892 as Monotherapy and Combination in MTAP-deleted Advanced Solid Tumors

Who this might be right for
NSCLC AdenocarcinomaGastroesophageal Cancer (GC)Gastric Adenocarcinoma+8 more
IDEAYA Biosciences 260
Early research (Phase 1)Looking for participantsNCT06973863
What this trial is testing

PEP08 in Patients With MTAP-Del Advanced or Metastatic Solid Tumors

Who this might be right for
Advanced Solid TumorSolid TumorsMTAP-deleted Solid Tumors+1 more
PharmaEngine 40
Early research (Phase 1)Looking for participantsNCT07077434
What this trial is testing

Assess Safety, Tolerability and Drug Levels of BMS-986504 in Participants With Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumors
Bristol-Myers Squibb 32
Early research (Phase 1)Ended earlyNCT03435250
What this trial is testing

Study of AG-270 in Participants With Advanced Solid Tumors or Lymphoma With MTAP Loss

Who this might be right for
Advanced Solid TumorsLymphoma
Institut de Recherches Internationales Servier 123
Early research (Phase 1)Looking for participantsNCT07128303
What this trial is testing

Study of GS-5319 in Adults With Solid Tumors

Who this might be right for
Advanced Solid Tumor
Gilead Sciences 178
Early research (Phase 1)Looking for participantsNCT06796699
What this trial is testing

A Phase Ia/Ib Clinical Study of GH56 Capsules in Subjects With MTAP-Deleted Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumors With MTAP Gene Deletion
Suzhou Genhouse Bio Co., Ltd. 90
Early research (Phase 1)Looking for participantsNCT07532902
What this trial is testing

BMS-986504 With Standard-of-Care Therapy for People With Solid Tumor Cancer

Who this might be right for
Diffuse Pleural MesotheliomaGastroesophageal CarcinomaUrothelial Carcinoma
Memorial Sloan Kettering Cancer Center 60
Early research (Phase 1)Looking for participantsNCT06672523
What this trial is testing

Evaluate the Mass Balance, Metabolism, Elimination, and Drug Levels of [14C]-BMS-986504 (MRTX1719) in Participants With Advanced Solid Tumors With Homozygous Methylthioadenosine Phosphorylase Deletion

Who this might be right for
Advanced Solid Tumors With Homozygous MTAP Deletion
Bristol-Myers Squibb 8
Testing effectiveness (Phase 2)Ended earlyNCT05275478
What this trial is testing

Safety and Tolerability of TNG908 in Patients With MTAP-deleted Solid Tumors

Who this might be right for
Locally Advanced Solid Tumor
Tango Therapeutics, Inc. 110
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