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Results for “MTAP-deleted Solid Tumors”

27 trials

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Showing 20 of 27 results

Early research (Phase 1)Ended earlyNCT03435250
What this trial is testing

Study of AG-270 in Participants With Advanced Solid Tumors or Lymphoma With MTAP Loss

Who this might be right for
Advanced Solid TumorsLymphoma
Institut de Recherches Internationales Servier 123
Early research (Phase 1)Active Not RecruitingNCT04794699
What this trial is testing

Study of IDE397 in Participants With Solid Tumors Harboring MTAP Deletion

Who this might be right for
Solid Tumor
IDEAYA Biosciences 169
Early research (Phase 1)Not Yet RecruitingNCT07583771
What this trial is testing

A Phase Ⅰ Study of CS08399 in Participants With MTAP-deleted Solid Tumors and Lymphoma

Who this might be right for
Pancreatic AdenocarcinomaNon Small Cell Lung CancerAdvanced Solid Tumors+2 more
Chipscreen Biosciences, Ltd. 186
Early research (Phase 1)Looking for participantsNCT05245500
What this trial is testing

Phase 1 Study of MRTX1719 in Solid Tumors With MTAP Deletion

Who this might be right for
MesotheliomaNon Small Cell Lung CancerMalignant Peripheral Nerve Sheath Tumors+3 more
Bristol-Myers Squibb 336
Early research (Phase 1)Looking for participantsNCT07469982
What this trial is testing

A Phase I Study of SY-9453 in Patients With Advanced Solid Tumors

Who this might be right for
Advanced or Metastatic Solid Tumors With Homozygous MTAP Deletion
Shouyao Holdings (Beijing) Co. LTD 122
Early research (Phase 1)Looking for participantsNCT06973863
What this trial is testing

PEP08 in Patients With MTAP-Del Advanced or Metastatic Solid Tumors

Who this might be right for
Advanced Solid TumorSolid TumorsMTAP-deleted Solid Tumors+1 more
PharmaEngine 40
Early research (Phase 1)Not Yet RecruitingNCT07567859
What this trial is testing

HS-10587 in Patients With Advanced Solid Tumors

Who this might be right for
MTAP Deletion
Jiangsu Hansoh Pharmaceutical Co., Ltd. 362
Testing effectiveness (Phase 2)Active Not RecruitingNCT06188702
What this trial is testing

S095035 as a Single Agent and in Combination in Adult Participants With Advanced or Metastatic Solid Tumors With Deletion of MTAP

Who this might be right for
MTAP-deleted Solid Tumors
Servier Bio-Innovation LLC 60
Early research (Phase 1)Looking for participantsNCT07128303
What this trial is testing

Study of GS-5319 Given Alone or in Combination in Adults With Solid Tumors

Who this might be right for
Advanced Solid Tumor
Gilead Sciences 476
Early research (Phase 1)Ended earlyNCT06568614
What this trial is testing

An Investigational Study of BG-89894 Tablets in Participants With Advanced Solid Tumors

Who this might be right for
Advanced or Metastatic MTAP-deleted Solid Tumors
BeOne Medicines 29
Testing effectiveness (Phase 2)Looking for participantsNCT06630416
What this trial is testing

Pemetrexed Response in Relation to Tumor Alterations of Gene Status for the Treatment of Patients With Metastatic Urothelial Bladder Cancer and Other Solid Tumors

Who this might be right for
Metastatic Bladder Urothelial CarcinomaMetastatic Malignant Solid NeoplasmStage IV Bladder Cancer AJCC v8+1 more
Northwestern University 64
Not applicableStudy completedNCT03361358
What this trial is testing

Pre-Screening Study to Identify MTAP Loss in Advanced Solid Tumors or Lymphoma

Who this might be right for
Advanced Solid TumorsLymphoma
Agios Pharmaceuticals, Inc. 44
Early research (Phase 1)Looking for participantsNCT06672523
What this trial is testing

Evaluate the Mass Balance, Metabolism, Elimination, and Drug Levels of [14C]-BMS-986504 (MRTX1719) in Participants With Advanced Solid Tumors With Homozygous Methylthioadenosine Phosphorylase Deletion

Who this might be right for
Advanced Solid Tumors With Homozygous MTAP Deletion
Bristol-Myers Squibb 8
Early research (Phase 1)Not Yet RecruitingNCT07699757
What this trial is testing

HSK41959 With Standard Therapy in Solid Tumors With MTAP Deletion

Who this might be right for
Non-Small Cell Lung CancerPancreatic Ductal Adenocarcinoma (mPDAC)Advanced Solid Tumors
Haisco Pharmaceutical Group Co., Ltd. 258
Testing effectiveness (Phase 2)Looking for participantsNCT07492680
What this trial is testing

BMS-986504 Monotherapy and in Combination With Other Agents in Participants With Advanced and/or Metastatic Solid Tumors With Homozygous MTAP Deletion (MountainTAP-5)

Who this might be right for
Solid Tumors
Bristol-Myers Squibb 260
Testing effectiveness (Phase 2)Ended earlyNCT05275478
What this trial is testing

Safety and Tolerability of TNG908 in Patients With MTAP-deleted Solid Tumors

Who this might be right for
Locally Advanced Solid Tumor
Tango Therapeutics, Inc. 110
Early research (Phase 1)Looking for participantsNCT07532902
What this trial is testing

BMS-986504 With Standard-of-Care Therapy for People With Solid Tumor Cancer

Who this might be right for
Diffuse Pleural MesotheliomaGastroesophageal CarcinomaUrothelial Carcinoma
Memorial Sloan Kettering Cancer Center 60
Early research (Phase 1)Looking for participantsNCT07071090
What this trial is testing

DC50292A Tablet in Patients With MTAP-deleted Advanced or Metastatic Solid Tumors

Who this might be right for
Solid Tumor Malignancies
Heronova Pharmaceuticals 32
Early research (Phase 1)Looking for participantsNCT07077434
What this trial is testing

Assess Safety, Tolerability and Drug Levels of Navlimetostat (BMS-986504) in Participants With Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumors
Bristol-Myers Squibb 32
Early research (Phase 1)Looking for participantsNCT07277413
What this trial is testing

IDE892 as Monotherapy and Combination in MTAP-deleted Advanced Solid Tumors

Who this might be right for
NSCLC AdenocarcinomaGastroesophageal Cancer (GC)Gastric Adenocarcinoma+10 more
IDEAYA Biosciences 260
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