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Results for “MTOR”

313 trials

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Showing 20 of 313 results

Testing effectiveness (Phase 2)Ended earlyNCT00727207
What this trial is testing

Everolimus in Treating Older Patients With Mantle Cell Lymphoma Previously Treated With First-Line or Second-Line Chemotherapy

Who this might be right for
Lymphoma
Technical University of Munich 35
Testing effectiveness (Phase 2)UnknownNCT01088893
What this trial is testing

Everolimus in Breast Cancer Patients After Pre-operative Chemotherapy

Who this might be right for
Breast Neoplasms
Organisation for Oncology and Translational Research 50
Post-approval studies (Phase 4)Study completedNCT02328963
What this trial is testing

Proportion of CMV Seropositive Kidney Transplant Recipients Who Will Develop a CMV Infection When Treated With an Immunosuppressive Regimen Including Everolimus and Reduced Dose of Cyclosporine Versus an Immunosuppressive Regimen With Mycophenolic Acid and Standard Dose of Cyclosporine A

Who this might be right for
Transplantation InfectionCytomegalovirus Infection
University Hospital, Bordeaux 186
Testing effectiveness (Phase 2)WithdrawnNCT01290406
What this trial is testing

BEZ235 Trial in Patients With Advanced Endometrial Carcinoma

Who this might be right for
Endometrial Cancer
Novartis Pharmaceuticals
Testing effectiveness (Phase 2)Study completedNCT05781698
What this trial is testing

Repurposing Fenofibrate in Modulating mTOR/NLRP3 Inflammasome in Patients With Ulcerative Colitis

Who this might be right for
Inflammatory Bowel Diseases
Tanta University 60
Testing effectiveness (Phase 2)Study completedNCT00560963
What this trial is testing

Treatment of Patients Suffering From a Progressive Pancreas Carcinoma With Everolimus (RAD001) and Gemcitabine

Who this might be right for
Advanced or Metastatic Pancreatic Adenocarcinoma
Novartis Pharmaceuticals 21
Testing effectiveness (Phase 2)Study completedNCT00975819
What this trial is testing

Safety and Efficacy Study of Sirolimus in Complicated Vascular Anomalies

Who this might be right for
Kaposiform HemangioendotheliomasTufted AngiomaCapillary Venous Lymphatic Malformation+6 more
Denise Martin Adams 61
Testing effectiveness (Phase 2)Study completedNCT03522298
What this trial is testing

Safety, Pharmacokinetics and Efficacy of Paxalisib (GDC-0084) in Newly-diagnosed Glioblastoma

Who this might be right for
Glioblastoma, Adult
Kazia Therapeutics Limited 30
Early research (Phase 1)Study completedNCT01122199
What this trial is testing

Study of RAD001 + AMG479 for Patients With Advanced Solid Tumors

Who this might be right for
Neoplasm Metastases
Shadia Jalal 27
Not applicableStudy completedNCT05054166
What this trial is testing

Efficacy of Everolimus-containing Chemotherapy in HER2- mBC Patients With PI3K/AKT/mTOR Mutations Study

Who this might be right for
Breast CancerPI3K/AKT/mTOR Pathway MutationEverolimus
Zhejiang Cancer Hospital 14
Early research (Phase 1)Study completedNCT00060645
What this trial is testing

Safety Study of AP23573 in Patients With Advanced, Refractory or Recurrent Malignancies (8669-013)(COMPLETED)

Who this might be right for
TumorsLymphomaMultiple Myeloma
Merck Sharp & Dohme LLC 33
Testing effectiveness (Phase 2)Study completedNCT01510119
What this trial is testing

Autophagy Inhibition to Augment Mammilian Target of Rapamycin (mTOR) Inhibition: A Phase I/II Trial of RAD001 and Hydroxychloroquine (HCQ) in Patients With Previously Treated Renal Cell Carcinoma

Who this might be right for
Metastatic Clear Cell Renal Cell Carcinoma
Abramson Cancer Center at Penn Medicine 40
Testing effectiveness (Phase 2)Study completedNCT00770120
What this trial is testing

S0722: Everolimus in Treating Patients With Pleural Malignant Mesothelioma That Cannot Be Removed By Surgery

Who this might be right for
Malignant Mesothelioma
SWOG Cancer Research Network 61
Testing effectiveness (Phase 2)Ended earlyNCT00811590
What this trial is testing

Pilot Study of mTOR Inhibitor Therapy in Peutz-Jeghers Syndrome

Who this might be right for
Peutz-Jeghers Syndrome
University of Utah 3
Not applicableEnded earlyNCT03946774
What this trial is testing

Dietary Protein and Monocyte/Macrophage Mammalian Target of Rapamycin (mTOR) Signaling

Who this might be right for
Dietary Protein
Washington University School of Medicine 21
Testing effectiveness (Phase 2)Active Not RecruitingNCT03047213
What this trial is testing

Sapanisertib in Treating Patients With Locally Advanced or Metastatic Bladder Cancer With TSC1 and/or TSC2 Mutations

Who this might be right for
Locally Advanced Bladder Urothelial CarcinomaMetastatic Transitional Cell CarcinomaMetastatic Urothelial Carcinoma+3 more
National Cancer Institute (NCI) 17
Post-approval studies (Phase 4)WithdrawnNCT04936971
What this trial is testing

Introduction of mTor Inhibitors and the Activation of the Cytomegalovirus (CMV) -Specific Cellular Immune Response

Who this might be right for
Kidney TransplantationCytomegalovirus Infections
Edoardo Melilli
Early research (Phase 1)WithdrawnNCT01194193
What this trial is testing

Preliminary Anti-tumour Activity of mTor Kinase Inhibitor in Advanced Tumours

Who this might be right for
CancerAdvanced Solid TumoursLymphomas
AstraZeneca 63
Testing effectiveness (Phase 2)UnknownNCT03664115
What this trial is testing

Itraconazole in Non Small Cell Lung Cancer

Who this might be right for
Lung Cancer
Ain Shams University 60
Large-scale testing (Phase 3)Study completedNCT01707849
What this trial is testing

The Impact of Everolimus Based Immunosuppression in the Evolution of Hepatitis C Fibrosis After Liver Transplantation

Who this might be right for
Hepatitis C Recurrence After Liver Transplant
Hospital Vall d'Hebron 18
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