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Results for “Macrophage Activation Syndrome”

26 trials

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Showing 20 of 26 results

Large-scale testing (Phase 3)UnknownNCT05137496
What this trial is testing

Ruxolitinib and Methylprednisolone as a First-line Treatment for Macrophage Activation Syndrome

Who this might be right for
Macrophage Activation Syndrome
Beijing Friendship Hospital 40
Testing effectiveness (Phase 2)Active Not RecruitingNCT02061800
What this trial is testing

CD34+ (Malignant) Stem Cell Selection for Patients Receiving Allogenic Stem Cell Transplant

Who this might be right for
Chronic Myeloid Leukemia (CML)Acute Myelogenous Leukemia (AML)Myelodysplastic Syndrome (MDS)+3 more
Diane George 14
Not applicableStudy completedNCT03721809
What this trial is testing

Characterization of the Inflammatory Profile of Patients With Macrophage Activation Syndrome Secondary to Bacterial Sepsis

Who this might be right for
Macrophage Activation Syndrome
University Hospital, Rouen 27
Not applicableStudy completedNCT00001000
What this trial is testing

Atvogen in Healthy Volunteers and HIV-Infected Patients Who Have No Symptoms of Infection

Who this might be right for
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID) 20
Not applicableLooking for participantsNCT07312474
What this trial is testing

Epidemiological, Clinical and Biological Characteristics of Human Anaplasmosis Cases in Alsace

Who this might be right for
Human Anaplasmosis
University Hospital, Strasbourg, France 100
Not applicableStudy completedNCT06992505
What this trial is testing

Assessment of Macrophage Activation syndromE in STill's Disease in Italy

Who this might be right for
Macrophage Activation Syndrome (MAS)Still Disease, Juvenile OnsetStill's Disease, Adult-Onset
Swedish Orphan Biovitrum 32
Testing effectiveness (Phase 2)Active Not RecruitingNCT05611710
What this trial is testing

Anakinra in Dengue With Hyperinflammation ( AnaDen )

Who this might be right for
DengueDengue With Warning SignsSevere Dengue+6 more
Oxford University Clinical Research Unit, Vietnam 160
Large-scale testing (Phase 3)Study completedNCT05001737
What this trial is testing

Evaluate Efficacy, Safety and Tolerability, PK and PD of Emapalumab in Children and Adults With MAS in Still's or SLE

Who this might be right for
Macrophage Activation SyndromeSecondary Hemophagocytic LymphohistiocytosisStill Disease+4 more
Swedish Orphan Biovitrum 33
Testing effectiveness (Phase 2)Study completedNCT03311854
What this trial is testing

Investigate the Safety and Efficacy of Emapalumab, an Anti-IFN-gamma mAb in Patients With Systemic Juvenile Idiopathic Arthritis (sJIA) or Adult-onset Still's Disease (AOSD) Developing Macrophage Activation Syndrome/Secondary HLH (MAS/sHLH)

Who this might be right for
Macrophage Activation SyndromeLymphohistiocytosis, HemophagocyticArthritis, Juvenile+1 more
Swedish Orphan Biovitrum 14
Not applicableStudy completedNCT02545621
What this trial is testing

A Role for RAGE/TXNIP/Inflammasome Axis in Alveolar Macrophage Activation During ARDS (RIAMA): a Proof-of-concept Clinical Study

Who this might be right for
Acute Respiratory Distress SyndromeMechanical Ventilation
University Hospital, Clermont-Ferrand 20
Not applicableLooking for participantsNCT06339177
What this trial is testing

Hemophagocytic Lymphohistiocytosis (HLH) Evaluation and Research of Clinical, ImmUnoLogic and TranscriptomE Study

Who this might be right for
Lymphohistiocytosis, HemophagocyticSecondary Hemophagocytic LymphohistiocytosisMacrophage Activation Syndrome+1 more
National Institute of Allergy and Infectious Diseases (NIAID) 300
Not applicableActive Not RecruitingNCT03827343
What this trial is testing

Retrospective Study of Immunotherapy Related Toxicities and Factors Impacting Outcomes in Children and Adults With Cancer

Who this might be right for
Macrophage Activation SyndromePrimary Hemophagocytic Lymphohistiocytosis
National Cancer Institute (NCI) 500
Early research (Phase 1)Ended earlyNCT02780583
What this trial is testing

Treatment of Macrophage Activation Syndrome (MAS) With Anakinra

Who this might be right for
Macrophage Activation Syndrome
University of Alabama at Birmingham 9
Post-approval studies (Phase 4)Study completedNCT01600170
What this trial is testing

Downmodulating Monocyte Activation for HIV-1 Associated Neurocognitive Disorders (HAND)

Who this might be right for
HIV Dementia
University of Pennsylvania 11
Not applicableUnknownNCT04347460
What this trial is testing

Establishing a COVID-19 Prospective Cohort for Identification of Secondary HLH

Who this might be right for
COVID
Technical University of Munich 20
Not applicableStudy completedNCT06405152
What this trial is testing

Assessment of Macrophage Activation syndromE in STill's Disease

Who this might be right for
Macrophage Activation SyndromeStill's Disease, Adult-OnsetStills Disease, Juvenile-Onset
Swedish Orphan Biovitrum 75
Not applicableStudy completedNCT00002433
What this trial is testing

The Effects of r-metHuIFN-Gamma on the Lungs of Patients With AIDS

Who this might be right for
HIV Infections
Amgen 12
Not applicableUnknownNCT01095146
What this trial is testing

New Candidate Criteria for Diagnosis of Macrophage Activation Syndrome

Who this might be right for
Macrophage Activation SyndromeLymphohistiocytosis, Hemophagocytic
Amrita Institute of Medical Sciences & Research Center 50
Testing effectiveness (Phase 2)Study completedNCT07034209
What this trial is testing

Evaluate the Efficacy, Safety, Tolerability, Pharmacokinetic Characteristics, and Immunogenicity of Plonmarlimab in Subjects With Rheumatic and Immunological Disease-associated Haemophagocytic Lymphohistiocytosis (HLH) (Also Known as Macrophage Activation Syndrome (MAS))

Who this might be right for
Hemophagocytic Lymphohistiocytoses
TJ Biopharma Co., Ltd. 18
Testing effectiveness (Phase 2)UnknownNCT02569463
What this trial is testing

Low-dose IL-2 ( Interleukin-2) Treatment in Macrophage Activation Syndrome（MAS）

Who this might be right for
Macrophage Activation Syndrome
Peking University People's Hospital 6
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