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Results for “Macrophage Activation Syndrome”

27 trials

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Showing 20 of 27 results

Not applicableStudy completedNCT03721809
What this trial is testing

Characterization of the Inflammatory Profile of Patients With Macrophage Activation Syndrome Secondary to Bacterial Sepsis

Who this might be right for
Macrophage Activation Syndrome
University Hospital, Rouen 27
Large-scale testing (Phase 3)Study completedNCT05001737
What this trial is testing

Evaluate Efficacy, Safety and Tolerability, PK and PD of Emapalumab in Children and Adults With MAS in Still's or SLE

Who this might be right for
Macrophage Activation SyndromeSecondary Hemophagocytic LymphohistiocytosisStill Disease+4 more
Swedish Orphan Biovitrum 33
Not applicableActive Not RecruitingNCT03827343
What this trial is testing

Retrospective Study of Immunotherapy Related Toxicities and Factors Impacting Outcomes in Children and Adults With Cancer

Who this might be right for
Macrophage Activation SyndromePrimary Hemophagocytic Lymphohistiocytosis
National Cancer Institute (NCI) 500
Large-scale testing (Phase 3)UnknownNCT05137496
What this trial is testing

Ruxolitinib and Methylprednisolone as a First-line Treatment for Macrophage Activation Syndrome

Who this might be right for
Macrophage Activation Syndrome
Beijing Friendship Hospital 40
Not applicableStudy completedNCT06992505
What this trial is testing

Assessment of Macrophage Activation syndromE in STill's Disease in Italy

Who this might be right for
Macrophage Activation Syndrome (MAS)Still Disease, Juvenile OnsetStill's Disease, Adult-Onset
Swedish Orphan Biovitrum 32
Not applicableLooking for participantsNCT06339177
What this trial is testing

Hemophagocytic Lymphohistiocytosis (HLH) Evaluation and Research of Clinical, ImmUnoLogic and TranscriptomE Study

Who this might be right for
Lymphohistiocytosis, HemophagocyticSecondary Hemophagocytic LymphohistiocytosisMacrophage Activation Syndrome+1 more
National Institute of Allergy and Infectious Diseases (NIAID) 300
Not applicableStudy completedNCT02545621
What this trial is testing

A Role for RAGE/TXNIP/Inflammasome Axis in Alveolar Macrophage Activation During ARDS (RIAMA): a Proof-of-concept Clinical Study

Who this might be right for
Acute Respiratory Distress SyndromeMechanical Ventilation
University Hospital, Clermont-Ferrand 20
Not applicableStudy completedNCT00002433
What this trial is testing

The Effects of r-metHuIFN-Gamma on the Lungs of Patients With AIDS

Who this might be right for
HIV Infections
Amgen 12
Testing effectiveness (Phase 2)UnknownNCT02569463
What this trial is testing

Low-dose IL-2 ( Interleukin-2) Treatment in Macrophage Activation Syndrome（MAS）

Who this might be right for
Macrophage Activation Syndrome
Peking University People's Hospital 6
Testing effectiveness (Phase 2)Study completedNCT03311854
What this trial is testing

Investigate the Safety and Efficacy of Emapalumab, an Anti-IFN-gamma mAb in Patients With Systemic Juvenile Idiopathic Arthritis (sJIA) or Adult-onset Still's Disease (AOSD) Developing Macrophage Activation Syndrome/Secondary HLH (MAS/sHLH)

Who this might be right for
Macrophage Activation SyndromeLymphohistiocytosis, HemophagocyticArthritis, Juvenile+1 more
Swedish Orphan Biovitrum 14
Not applicableStudy completedNCT02854943
What this trial is testing

Investigation of Ferritin in Critically Ill Patients With Hemophagocytic Lymphohistiocytosis

Who this might be right for
Hemophagocytic Lymphohistiocytosis (HLH)Macrophage Activation Syndrome (MAS)Hemophagocytic Syndromes
Gunnar Lachmann 2,623
Not applicableStudy completedNCT06405152
What this trial is testing

Assessment of Macrophage Activation syndromE in STill's Disease

Who this might be right for
Macrophage Activation SyndromeStill's Disease, Adult-OnsetStills Disease, Juvenile-Onset
Swedish Orphan Biovitrum 75
Testing effectiveness (Phase 2)Study completedNCT04339712
What this trial is testing

Personalised Immunotherapy for SARS-CoV-2 (COVID-19) Associated With Organ Dysfunction

Who this might be right for
COVID-19Virus DiseasesMacrophage Activation Syndrome+1 more
Hellenic Institute for the Study of Sepsis 102
Not applicableUnknownNCT04347460
What this trial is testing

Establishing a COVID-19 Prospective Cohort for Identification of Secondary HLH

Who this might be right for
COVID
Technical University of Munich 20
Testing effectiveness (Phase 2)Active Not RecruitingNCT02061800
What this trial is testing

CD34+ (Malignant) Stem Cell Selection for Patients Receiving Allogenic Stem Cell Transplant

Who this might be right for
Chronic Myeloid Leukemia (CML)Acute Myelogenous Leukemia (AML)Myelodysplastic Syndrome (MDS)+3 more
Diane George 14
Testing effectiveness (Phase 2)Active Not RecruitingNCT01966367
What this trial is testing

CD34+ (Non-Malignant) Stem Cell Selection for Patients Receiving Allogeneic Stem Cell Transplantation

Who this might be right for
Bone Marrow Failure SyndromeSevere Aplastic AnemiaSevere Congenital Neutropenia+13 more
Diane George 37
Not applicableNot Yet RecruitingNCT07491926
What this trial is testing

MASKd: a Study on Kawasaki Disease (KD) Complicated by Macrophage Activation Syndrome (MAS)

Who this might be right for
Kawasaki DiseaseMacrophage Activation Syndrome (MAS)
Meyer Children's Hospital IRCCS 150
Not applicableLooking for participantsNCT07312474
What this trial is testing

Epidemiological, Clinical and Biological Characteristics of Human Anaplasmosis Cases in Alsace

Who this might be right for
Human Anaplasmosis
University Hospital, Strasbourg, France 100
Testing effectiveness (Phase 2)Study completedNCT03332225
What this trial is testing

A Trial of Validation and Restoration of Immune Dysfunction in Severe Infections and Sepsis

Who this might be right for
SepsisMacrophage Activation Syndrome
Hellenic Institute for the Study of Sepsis 36
Early research (Phase 1)Ended earlyNCT02780583
What this trial is testing

Treatment of Macrophage Activation Syndrome (MAS) With Anakinra

Who this might be right for
Macrophage Activation Syndrome
University of Alabama at Birmingham 9
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