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Results for “Macrophage Activation Syndrome (MAS)”

21 trials

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Showing 20 of 21 results

Not applicableStudy completedNCT06405152
What this trial is testing

Assessment of Macrophage Activation syndromE in STill's Disease

Who this might be right for
Macrophage Activation SyndromeStill's Disease, Adult-OnsetStills Disease, Juvenile-Onset
Swedish Orphan Biovitrum 75
Testing effectiveness (Phase 2)Study completedNCT04339712
What this trial is testing

Personalised Immunotherapy for SARS-CoV-2 (COVID-19) Associated With Organ Dysfunction

Who this might be right for
COVID-19Virus DiseasesMacrophage Activation Syndrome+1 more
Hellenic Institute for the Study of Sepsis 102
Testing effectiveness (Phase 2)Active Not RecruitingNCT02061800
What this trial is testing

CD34+ (Malignant) Stem Cell Selection for Patients Receiving Allogenic Stem Cell Transplant

Who this might be right for
Chronic Myeloid Leukemia (CML)Acute Myelogenous Leukemia (AML)Myelodysplastic Syndrome (MDS)+3 more
Diane George 14
Not applicableLooking for participantsNCT07312474
What this trial is testing

Epidemiological, Clinical and Biological Characteristics of Human Anaplasmosis Cases in Alsace

Who this might be right for
Human Anaplasmosis
University Hospital, Strasbourg, France 100
Large-scale testing (Phase 3)Study completedNCT05001737
What this trial is testing

Evaluate Efficacy, Safety and Tolerability, PK and PD of Emapalumab in Children and Adults With MAS in Still's or SLE

Who this might be right for
Macrophage Activation SyndromeSecondary Hemophagocytic LymphohistiocytosisStill Disease+4 more
Swedish Orphan Biovitrum 33
Testing effectiveness (Phase 2)Study completedNCT07034209
What this trial is testing

Evaluate the Efficacy, Safety, Tolerability, Pharmacokinetic Characteristics, and Immunogenicity of Plonmarlimab in Subjects With Rheumatic and Immunological Disease-associated Haemophagocytic Lymphohistiocytosis (HLH) (Also Known as Macrophage Activation Syndrome (MAS))

Who this might be right for
Hemophagocytic Lymphohistiocytoses
TJ Biopharma Co., Ltd. 18
Not applicableUnknownNCT04347460
What this trial is testing

Establishing a COVID-19 Prospective Cohort for Identification of Secondary HLH

Who this might be right for
COVID
Technical University of Munich 20
Not applicableUnknownNCT01095146
What this trial is testing

New Candidate Criteria for Diagnosis of Macrophage Activation Syndrome

Who this might be right for
Macrophage Activation SyndromeLymphohistiocytosis, Hemophagocytic
Amrita Institute of Medical Sciences & Research Center 50
Not applicableLooking for participantsNCT06339177
What this trial is testing

Hemophagocytic Lymphohistiocytosis (HLH) Evaluation and Research of Clinical, ImmUnoLogic and TranscriptomE Study

Who this might be right for
Lymphohistiocytosis, HemophagocyticSecondary Hemophagocytic LymphohistiocytosisMacrophage Activation Syndrome+1 more
National Institute of Allergy and Infectious Diseases (NIAID) 300
Testing effectiveness (Phase 2)Study completedNCT03311854
What this trial is testing

Investigate the Safety and Efficacy of Emapalumab, an Anti-IFN-gamma mAb in Patients With Systemic Juvenile Idiopathic Arthritis (sJIA) or Adult-onset Still's Disease (AOSD) Developing Macrophage Activation Syndrome/Secondary HLH (MAS/sHLH)

Who this might be right for
Macrophage Activation SyndromeLymphohistiocytosis, HemophagocyticArthritis, Juvenile+1 more
Swedish Orphan Biovitrum 14
Large-scale testing (Phase 3)Looking for participantsNCT07208058
What this trial is testing

A Phase III Clinical Study to Evaluate the Efficacy, Safety, and Tolerability of Plonmarlimab in Subjects With Relapsed/Refractory Rheumatic and Immunologic Disease-associated Haemophagocytic Lymphohistiocytosis (Also Known as Macrophage Activation Syndrome [MAS])

Who this might be right for
Relapsed/Refractory Rheumatic and Immunologic Disease-associated Haemophagocytic Lymphohistiocytosis
TJ Biopharma Co., Ltd. 30
Testing effectiveness (Phase 2)Study completedNCT03332225
What this trial is testing

A Trial of Validation and Restoration of Immune Dysfunction in Severe Infections and Sepsis

Who this might be right for
SepsisMacrophage Activation Syndrome
Hellenic Institute for the Study of Sepsis 36
Large-scale testing (Phase 3)UnknownNCT05137496
What this trial is testing

Ruxolitinib and Methylprednisolone as a First-line Treatment for Macrophage Activation Syndrome

Who this might be right for
Macrophage Activation Syndrome
Beijing Friendship Hospital 40
Not applicableStudy completedNCT02854943
What this trial is testing

Investigation of Ferritin in Critically Ill Patients With Hemophagocytic Lymphohistiocytosis

Who this might be right for
Hemophagocytic Lymphohistiocytosis (HLH)Macrophage Activation Syndrome (MAS)Hemophagocytic Syndromes
Gunnar Lachmann 2,623
Testing effectiveness (Phase 2)Active Not RecruitingNCT05611710
What this trial is testing

Anakinra in Dengue With Hyperinflammation ( AnaDen )

Who this might be right for
DengueDengue With Warning SignsSevere Dengue+6 more
Oxford University Clinical Research Unit, Vietnam 160
Testing effectiveness (Phase 2)UnknownNCT02569463
What this trial is testing

Low-dose IL-2 ( Interleukin-2) Treatment in Macrophage Activation Syndrome（MAS）

Who this might be right for
Macrophage Activation Syndrome
Peking University People's Hospital 6
Not applicableActive Not RecruitingNCT03827343
What this trial is testing

Retrospective Study of Immunotherapy Related Toxicities and Factors Impacting Outcomes in Children and Adults With Cancer

Who this might be right for
Macrophage Activation SyndromePrimary Hemophagocytic Lymphohistiocytosis
National Cancer Institute (NCI) 500
Not applicableStudy completedNCT06992505
What this trial is testing

Assessment of Macrophage Activation syndromE in STill's Disease in Italy

Who this might be right for
Macrophage Activation Syndrome (MAS)Still Disease, Juvenile OnsetStill's Disease, Adult-Onset
Swedish Orphan Biovitrum 32
Early research (Phase 1)Ended earlyNCT02780583
What this trial is testing

Treatment of Macrophage Activation Syndrome (MAS) With Anakinra

Who this might be right for
Macrophage Activation Syndrome
University of Alabama at Birmingham 9
Not applicableStudy completedNCT03721809
What this trial is testing

Characterization of the Inflammatory Profile of Patients With Macrophage Activation Syndrome Secondary to Bacterial Sepsis

Who this might be right for
Macrophage Activation Syndrome
University Hospital, Rouen 27
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