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Results for “Malignant Childhood Central Nervous System Neoplasm”

133 trials

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Showing 20 of 133 results

Early research (Phase 1)Ended earlyNCT00112619
What this trial is testing

Topotecan in Treating Young Patients With Neoplastic Meningitis Due to Leukemia, Lymphoma, or Solid Tumors

Who this might be right for
Brain and Central Nervous System TumorsCarcinoma of Unknown PrimaryLeukemia+2 more
Pediatric Brain Tumor Consortium 19
Testing effectiveness (Phase 2)Study completedNCT03233204
What this trial is testing

Olaparib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Defects in DNA Damage Repair Genes (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmAnn Arbor Stage III Childhood Non-Hodgkin LymphomaAnn Arbor Stage IV Childhood Non-Hodgkin Lymphoma+33 more
National Cancer Institute (NCI) 6
Testing effectiveness (Phase 2)Study completedNCT00024258
What this trial is testing

Arsenic Trioxide in Treating Patients With Advanced Neuroblastoma or Other Childhood Solid Tumors

Who this might be right for
Brain and Central Nervous System TumorsChildhood Germ Cell TumorExtragonadal Germ Cell Tumor+6 more
Memorial Sloan Kettering Cancer Center 22
Early research (Phase 1)Study completedNCT03565367
What this trial is testing

Hyperpolarized Carbon C 13 Pyruvate Magnetic Resonance Spectroscopic Imaging in Detecting Lactate and Bicarbonate in Participants With Central Nervous System Tumors

Who this might be right for
Malignant Central Nervous System NeoplasmMetastatic Malignant Neoplasm in the Central Nervous System
Daniel M. Spielman 9
Testing effectiveness (Phase 2)Study completedNCT00005811
What this trial is testing

Topotecan Hydrochloride in Treating Children With Meningeal Cancer That Has Not Responded to Previous Treatment

Who this might be right for
AIDS-related Diffuse Large Cell LymphomaAIDS-related Diffuse Mixed Cell LymphomaAIDS-related Diffuse Small Cleaved Cell Lymphoma+17 more
National Cancer Institute (NCI) 77
Early research (Phase 1)WithdrawnNCT04500548
What this trial is testing

Testing the Combination of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) in Children, Adolescent, and Young Adult Patients With Relapsed/Refractory Cancers That Have an Increased Number of Genetic Changes, The 3CI Study

Who this might be right for
Constitutional Mismatch Repair Deficiency SyndromeHematopoietic and Lymphoid Cell NeoplasmLynch Syndrome+9 more
National Cancer Institute (NCI)
Large-scale testing (Phase 3)Study completedNCT00008359
What this trial is testing

Caspofungin Acetate Compared With Amphotericin B Liposomal in Treating Patients With Persistent Fever and Neutropenia Following Cancer Treatment

Who this might be right for
Cancer
Memorial Sloan Kettering Cancer Center
Not applicableStudy completedNCT00165542
What this trial is testing

A-protein Levels in Adult and Pediatric Brain Tumor Patients

Who this might be right for
Malignant Childhood Central Nervous System Neoplasm
Dana-Farber Cancer Institute 54
Testing effectiveness (Phase 2)Active Not RecruitingNCT03698994
What this trial is testing

Ulixertinib in Treating Patients With Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With MAPK Pathway Mutations (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmRecurrent Ependymal TumorRecurrent Ewing Sarcoma+33 more
National Cancer Institute (NCI) 20
Early research (Phase 1)WithdrawnNCT03990597
What this trial is testing

StrataXRT in Preventing Radiation Dermatitis in Pediatric Patients Undergoing Radiation Therapy to the Brain or Spinal Cord

Who this might be right for
Central Nervous System SarcomaEpendymomaGlioma+4 more
M.D. Anderson Cancer Center
Not applicableStudy completedNCT04276194
What this trial is testing

Vertebral Body Sparing Craniospinal Irradiation for Pediatric Patients With Cancer of the Central Nervous System

Who this might be right for
Malignant Central Nervous System Neoplasm
Emory University 10
Not applicableStudy completedNCT00993694
What this trial is testing

Methemoglobinemia in Young Patients With Hematologic Cancer or Aplastic Anemia Treated With Dapsone

Who this might be right for
Chronic Myeloproliferative DisordersLeukemiaLymphoma+6 more
Vanderbilt University 41
Early research (Phase 1)Looking for participantsNCT03911388
What this trial is testing

HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors

Who this might be right for
Neoplasms, BrainGlioblastoma MultiformeGlioblastoma of Cerebellum+30 more
M.D. Anderson Cancer Center 24
Testing effectiveness (Phase 2)Study completedNCT00005955
What this trial is testing

Temozolomide Followed by Radiation Therapy in Treating Children With Newly Diagnosed Malignant CNS Tumors

Who this might be right for
Brain and Central Nervous System TumorsNeuroblastoma
Duke University
Testing effectiveness (Phase 2)Study completedNCT00095940
What this trial is testing

Lapatinib in Treating Young Patients With Recurrent or Refractory Central Nervous System Tumors

Who this might be right for
Recurrent Childhood Anaplastic AstrocytomaRecurrent Childhood Brain Stem GliomaRecurrent Childhood Ependymoma+5 more
National Cancer Institute (NCI) 52
Early research (Phase 1)WithdrawnNCT05720624
What this trial is testing

Pharmacodynamic Analyses of Metabolic Agents Following Brain Radiation

Who this might be right for
Malignant Central Nervous System Neoplasm
Mayo Clinic
Early research (Phase 1)Study completedNCT00303940
What this trial is testing

Talabostat Combined With Temozolomide or Carboplatin in Treating Young Patients With Relapsed or Refractory Brain Tumors or Other Solid Tumors

Who this might be right for
Brain and Central Nervous System TumorsChildhood Germ Cell TumorKidney Cancer+5 more
National Institutes of Health Clinical Center (CC) 26
Early research (Phase 1)Looking for participantsNCT06193759
What this trial is testing

Immunotherapy for Malignant Pediatric Brain Tumors Employing Adoptive Cellular Therapy (IMPACT)

Who this might be right for
Medulloblastoma, ChildhoodAtypical Teratoid/Rhabdoid Tumor of CNSEmbryonal Tumor With Multilayered Rosettes+2 more
Children's National Research Institute 12
Testing effectiveness (Phase 2)Study completedNCT00005952
What this trial is testing

Temozolomide Plus Peripheral Stem Cell Transplantation in Treating Children With Newly Diagnosed Malignant Glioma or Recurrent CNS or Other Solid Tumors

Who this might be right for
Brain and Central Nervous System TumorsChildhood Germ Cell TumorHead and Neck Cancer+5 more
Duke University 30
Testing effectiveness (Phase 2)Study completedNCT03213691
What this trial is testing

Selumetinib Sulfate in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Activating MAPK Pathway Mutations (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmAnn Arbor Stage III Childhood Non-Hodgkin LymphomaAnn Arbor Stage IV Childhood Non-Hodgkin Lymphoma+8 more
National Cancer Institute (NCI) 21
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