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Results for “Mavacamten”

36 trials

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Showing 20 of 36 results

Not applicableNot Yet RecruitingNCT07408427
What this trial is testing

Precision Pharmacogenetics and Genotype Class Based Prediction of Mavacamten Response in Obstructive Hypertrophic Cardiomyopathy

Who this might be right for
Hypertrophic Cardiomyopathy (HCM)
University of Manchester 140
Not applicableLooking for participantsNCT06146660
What this trial is testing

Assess the Safety of Mavacamten in Korean Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy

Who this might be right for
Obstructive Hypertrophic Cardiomyopathy
Bristol-Myers Squibb 600
Post-approval studies (Phase 4)Looking for participantsNCT07004972
What this trial is testing

Mavacamten in Adults With Obstructive Hypertrophic Cardiomyopathy in India (ROVER)

Who this might be right for
Symptomatic Obstructive Hypertrophic Cardiomyopathy
Bristol-Myers Squibb 50
Early research (Phase 1)Study completedNCT05719805
What this trial is testing

Evaluate the Effects of Mavacamten in Healthy Participants

Who this might be right for
Healthy Participants
Bristol-Myers Squibb 84
Large-scale testing (Phase 3)Study completedNCT04349072
What this trial is testing

Evaluate Mavacamten in Adults With Symptomatic Obstructive HCM Who Are Eligible for Septal Reduction Therapy

Who this might be right for
HOCM, Hypertrophic Obstructive Cardiomyopathy
Bristol-Myers Squibb 112
Large-scale testing (Phase 3)Study completedNCT05414175
What this trial is testing

Mavacamten in Obstructive Hypertrophic Cardiomyopathy

Who this might be right for
Cardiomyopathy, Hypertrophic Obstructive
Bristol-Myers Squibb 38
Testing effectiveness (Phase 2)Study completedNCT03442764
What this trial is testing

Mavacamten in Adults With Symptomatic Non-Obstructive Hypertrophic Cardiomyopathy (nHCM)

Who this might be right for
Non-obstructive Hypertrophic Cardiomyopathy
MyoKardia, Inc. 59
Not applicableActive Not RecruitingNCT06372457
What this trial is testing

COLLIGO-HCM: A Multinational Observational Study of the Real-World Effectiveness of Mavacamten Among Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy (oHCM)

Who this might be right for
Hypertrophic Cardiomyopathy (HCM)
Bristol-Myers Squibb 500
Early research (Phase 1)Study completedNCT05320094
What this trial is testing

Evaluate the Effect of Activated Charcoal With Sorbitol on the Single-dose of Mavacamten in Healthy Participants

Who this might be right for
Healthy Participants
Bristol-Myers Squibb 45
Post-approval studies (Phase 4)Active Not RecruitingNCT06112743
What this trial is testing

Evaluate Mavacamten Impact on Myocardial Structure in Participants With Symptomatic Obstructive Hypertrophic Cardiomyopathy

Who this might be right for
Cardiomyopathy, Hypertrophic
Bristol-Myers Squibb 63
Not applicableLooking for participantsNCT07383025
What this trial is testing

Mavacamten Post-marketing Surveillance in Patients With Obstructive Hypertrophic Cardiomyopathy in Japan

Who this might be right for
Obstructive Hypertrophic Cardiomyopathy (oHCM)
Bristol-Myers Squibb 200
Not applicableNot Yet RecruitingNCT07120776
What this trial is testing

Positron Emission Tomography to Assess the Effect of Camzyos on Ischaemia in HOCM: PEACH Trial

Who this might be right for
Hypertrophic Obstructive Cardiomyopathy \(HOCM\)Left Ventricular Outflow Tract ObstructionMyocardial Ischaemia
University of Manchester 75
Testing effectiveness (Phase 2)Study completedNCT03496168
What this trial is testing

Extension Study of Mavacamten (MYK-461) in Adults With Symptomatic Obstructive Hypertrophic Cardiomyopathy Previously Enrolled in PIONEER

Who this might be right for
Hypertrophic Cardiomyopathy
Bristol-Myers Squibb 13
Post-approval studies (Phase 4)Not Yet RecruitingNCT07103655
What this trial is testing

The Therapeutic Value of Mavacamten in Hypertrophic Cardiomyopathy With Mid-to-Apical Left Ventricular Obstruction

Who this might be right for
Hypertrophic Cardiomyopathy (HCM)
Second Affiliated Hospital, School of Medicine, Zhejiang University 132
Large-scale testing (Phase 3)Study completedNCT05582395
What this trial is testing

Mavacamten in Non-Obstructive Hypertrophic Cardiomyopathy

Who this might be right for
Cardiomyopathy, Hypertrophic
Bristol-Myers Squibb 580
Not applicableLooking for participantsNCT07155434
What this trial is testing

ENABLE-HCM - AI-ENabled Echocardiography With Ultrasound Beyond the Echo Lab for Better HCM Imaging and Expanded Access

Who this might be right for
Hypertrophic Cardiomyopathy (HCM)Cardiac ImagingEchocardiography+2 more
UltraSight 75
Testing effectiveness (Phase 2)Study completedNCT04766892
What this trial is testing

Mavacamten in Participants With HFpEF and Elevation of NT-proBNP With or Without Elevation of cTnT

Who this might be right for
Heart Failure With Preserved Ejection Fraction
Bristol-Myers Squibb 30
Large-scale testing (Phase 3)Active Not RecruitingNCT06253221
What this trial is testing

Evaluate Mavacamten in Adolescents With Symptomatic Obstructive Hypertrophic Cardiomyopathy

Who this might be right for
Cardiomyopathy, Hypertrophic
Bristol-Myers Squibb 44
Early research (Phase 1)Study completedNCT06211179
What this trial is testing

Assess the Relative Bioavailability of 5 mg Mavacamten Opened Capsule Administered Via Nasogastric Tube Compared to Intact Oral 5 mg Mavacamten in Healthy Participants

Who this might be right for
Healthy Volunteers
Bristol-Myers Squibb 34
Not applicableActive Not RecruitingNCT07107373
What this trial is testing

Assess the Treatment of Obstructive Hypertrophic Cardiomyopathy (oHCM) With Mavacamten in the US

Who this might be right for
Obstructive Hypertrophic Cardiomyopathy (oHCM)
Bristol-Myers Squibb 150
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