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Results for “Mavacamten”

38 trials

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Showing 20 of 38 results

Large-scale testing (Phase 3)Study completedNCT04349072
What this trial is testing

Evaluate Mavacamten in Adults With Symptomatic Obstructive HCM Who Are Eligible for Septal Reduction Therapy

Who this might be right for
HOCM, Hypertrophic Obstructive Cardiomyopathy
Bristol-Myers Squibb 112
Not applicableEnded earlyNCT07155434
What this trial is testing

ENABLE-HCM - AI-ENabled Echocardiography With Ultrasound Beyond the Echo Lab for Better HCM Imaging and Expanded Access

Who this might be right for
Hypertrophic Cardiomyopathy (HCM)Cardiac ImagingEchocardiography+2 more
UltraSight 36
Post-approval studies (Phase 4)Active Not RecruitingNCT06112743
What this trial is testing

Evaluate Mavacamten Impact on Myocardial Structure in Participants With Symptomatic Obstructive Hypertrophic Cardiomyopathy

Who this might be right for
Cardiomyopathy, Hypertrophic
Bristol-Myers Squibb 63
Large-scale testing (Phase 3)Study completedNCT05414175
What this trial is testing

Mavacamten in Obstructive Hypertrophic Cardiomyopathy

Who this might be right for
Cardiomyopathy, Hypertrophic Obstructive
Bristol-Myers Squibb 38
Early research (Phase 1)Study completedNCT05320094
What this trial is testing

Evaluate the Effect of Activated Charcoal With Sorbitol on the Single-dose of Mavacamten in Healthy Participants

Who this might be right for
Healthy Participants
Bristol-Myers Squibb 45
Not applicableStudy completedNCT06338202
What this trial is testing

Real-World Effectiveness of Mavacamten in Canada

Who this might be right for
Obstructive Hypertrophic Cardiomyopathy (oHCM)
Bristol-Myers Squibb 115
Not applicableActive Not RecruitingNCT06549608
What this trial is testing

A Retrospective Cohort Study of Mavacamten Patient Support Program in Canada

Who this might be right for
Hypertrophic Cardiomyopathy
Bristol-Myers Squibb 685
Not applicableLooking for participantsNCT07383025
What this trial is testing

Mavacamten Post-marketing Surveillance in Patients With Obstructive Hypertrophic Cardiomyopathy in Japan

Who this might be right for
Obstructive Hypertrophic Cardiomyopathy (oHCM)
Bristol-Myers Squibb 200
Testing effectiveness (Phase 2)Study completedNCT03496168
What this trial is testing

Extension Study of Mavacamten (MYK-461) in Adults With Symptomatic Obstructive Hypertrophic Cardiomyopathy Previously Enrolled in PIONEER

Who this might be right for
Hypertrophic Cardiomyopathy
Bristol-Myers Squibb 13
Early research (Phase 1)Study completedNCT05362045
What this trial is testing

Evaluate the Effects on the Single-Dose Drug Levels of Mavacamten in Healthy Participants

Who this might be right for
Healthy Participants
Bristol-Myers Squibb 158
Early research (Phase 1)Study completedNCT06211179
What this trial is testing

Assess the Relative Bioavailability of 5 mg Mavacamten Opened Capsule Administered Via Nasogastric Tube Compared to Intact Oral 5 mg Mavacamten in Healthy Participants

Who this might be right for
Healthy Volunteers
Bristol-Myers Squibb 34
Early research (Phase 1)Study completedNCT05658146
What this trial is testing

Assess the Effects on the Single-Dose Drug Levels of Mavacamten in Healthy Participants

Who this might be right for
Healthy Participants
Bristol-Myers Squibb 95
Not applicableNot Yet RecruitingNCT07120776
What this trial is testing

Positron Emission Tomography to Assess the Effect of Camzyos on Ischaemia in HOCM: PEACH Trial

Who this might be right for
Hypertrophic Obstructive Cardiomyopathy \(HOCM\)Left Ventricular Outflow Tract ObstructionMyocardial Ischaemia
University of Manchester 75
Not applicableNot Yet RecruitingNCT07408427
What this trial is testing

Precision Pharmacogenetics and Genotype Class Based Prediction of Mavacamten Response in Obstructive Hypertrophic Cardiomyopathy

Who this might be right for
Hypertrophic Cardiomyopathy (HCM)
University of Manchester 140
Post-approval studies (Phase 4)Looking for participantsNCT07004972
What this trial is testing

Mavacamten in Adults With Obstructive Hypertrophic Cardiomyopathy in India (ROVER)

Who this might be right for
Symptomatic Obstructive Hypertrophic Cardiomyopathy
Bristol-Myers Squibb 50
Early research (Phase 1)Study completedNCT05719805
What this trial is testing

Evaluate the Effects of Mavacamten in Healthy Participants

Who this might be right for
Healthy Participants
Bristol-Myers Squibb 84
Not applicableNot Yet RecruitingNCT07439952
What this trial is testing

Biological Collection for the Purpose of Exploring Genetic and Clinical-biological Factors Associated With Variability in Response to Mavacamten in the Treatment of Obstructive Hypertrophic Cardiomyopathy

Who this might be right for
Obstructive Hypertrophic Cardiomyopathy (oHCM)
Assistance Publique - Hôpitaux de Paris 300
Early research (Phase 1)Study completedNCT05135871
What this trial is testing

Study Evaluating the Pharmacokinetics of Mavacamten in Healthy Adult Chinese Subjects

Who this might be right for
Hypertrophic Cardiomyopathy
LianBio LLC 45
Not applicableNot Yet RecruitingNCT06856265
What this trial is testing

Efficacy of Mavacamten Combined With Radiofrequency Ablation in Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy

Who this might be right for
Obstructive Hypertrophic CardiomyopathyMavacamtenRadiofrequency Ablation
Shanghai Chest Hospital 40
Not applicableActive Not RecruitingNCT07107373
What this trial is testing

Assess the Treatment of Obstructive Hypertrophic Cardiomyopathy (oHCM) With Mavacamten in the US

Who this might be right for
Obstructive Hypertrophic Cardiomyopathy (oHCM)
Bristol-Myers Squibb 150
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