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Results for “Mavacamten”

45 trials

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Showing 20 of 45 results

Not applicableLooking for participantsNCT07361289
What this trial is testing

Assess the Real-World Effectiveness of Mavacamten in Adult Patients With Obstructive Hypertrophic Cardiomyopathy in China

Who this might be right for
Hypertrophic Cardiomyopathy
Bristol-Myers Squibb 500
Large-scale testing (Phase 3)Active Not RecruitingNCT06253221
What this trial is testing

Evaluate Mavacamten in Adolescents With Symptomatic Obstructive Hypertrophic Cardiomyopathy

Who this might be right for
Cardiomyopathy, Hypertrophic
Bristol-Myers Squibb 44
Early research (Phase 1)Study completedNCT05320094
What this trial is testing

Evaluate the Effect of Activated Charcoal With Sorbitol on the Single-dose of Mavacamten in Healthy Participants

Who this might be right for
Healthy Participants
Bristol-Myers Squibb 45
Post-approval studies (Phase 4)Not Yet RecruitingNCT07807384
What this trial is testing

Efficacy and Safety of an LVEF-Guided Mavacamten Dose Up-Titration Strategy in Chinese Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy

Who this might be right for
Obstructive Hypertrophic Cardiomyopathy (oHCM)
Second Affiliated Hospital of Nanchang University 115
Large-scale testing (Phase 3)Ended earlyNCT05582395
What this trial is testing

Mavacamten in Non-Obstructive Hypertrophic Cardiomyopathy

Who this might be right for
Cardiomyopathy, Hypertrophic
Bristol-Myers Squibb 580
Not applicableLooking for participantsNCT05939700
What this trial is testing

Mavacamten Pregnancy Surveillance Program

Who this might be right for
BreastfeedingHypertrophic CardiomyopathyPregnancy Related
Bristol-Myers Squibb 20
Not applicableNot Yet RecruitingNCT07815301
What this trial is testing

Gradual Tapering or Discontinuation of Beta-Blockers After Stabilization With Mavacamten Therapy

Who this might be right for
Obstructive Hypertrophic Cardiomyopathy (oHCM)
First Affiliated Hospital of Wenzhou Medical University 286
Not applicableStudy completedNCT06549608
What this trial is testing

A Retrospective Cohort Study of Mavacamten Patient Support Program in Canada

Who this might be right for
Hypertrophic Cardiomyopathy
Bristol-Myers Squibb 683
Early research (Phase 1)Study completedNCT05362045
What this trial is testing

Evaluate the Effects on the Single-Dose Drug Levels of Mavacamten in Healthy Participants

Who this might be right for
Healthy Participants
Bristol-Myers Squibb 158
Not applicableEnded earlyNCT07155434
What this trial is testing

ENABLE-HCM - AI-ENabled Echocardiography With Ultrasound Beyond the Echo Lab for Better HCM Imaging and Expanded Access

Who this might be right for
Hypertrophic Cardiomyopathy (HCM)Cardiac ImagingEchocardiography+2 more
UltraSight 36
Early research (Phase 1)Study completedNCT05658146
What this trial is testing

Assess the Effects on the Single-Dose Drug Levels of Mavacamten in Healthy Participants

Who this might be right for
Healthy Participants
Bristol-Myers Squibb 95
Not applicableActive Not RecruitingNCT06947590
What this trial is testing

Efficacy of Mavacamten in Patients With Symptomatic Latent Obstructive Hypertrophic Cardiomyopathy

Who this might be right for
HCM - Hypertrophic CardiomyopathyMavacamten
Xu Liu 78
Large-scale testing (Phase 3)Study completedNCT04349072
What this trial is testing

Evaluate Mavacamten in Adults With Symptomatic Obstructive HCM Who Are Eligible for Septal Reduction Therapy

Who this might be right for
HOCM, Hypertrophic Obstructive Cardiomyopathy
Bristol-Myers Squibb 112
Post-approval studies (Phase 4)Active Not RecruitingNCT07004972
What this trial is testing

Mavacamten in Adults With Obstructive Hypertrophic Cardiomyopathy in India (ROVER)

Who this might be right for
Symptomatic Obstructive Hypertrophic Cardiomyopathy
Bristol-Myers Squibb 50
Not applicableStudy completedNCT06338202
What this trial is testing

Real-World Effectiveness of Mavacamten in Canada

Who this might be right for
Obstructive Hypertrophic Cardiomyopathy (oHCM)
Bristol-Myers Squibb 115
Not applicableLooking for participantsNCT05489705
What this trial is testing

A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)

Who this might be right for
Obstructive Hypertrophic Cardiomyopathy
Bristol-Myers Squibb 1,700
Large-scale testing (Phase 3)Study completedNCT03723655
What this trial is testing

A Long-Term Safety Extension Study of Mavacamten in Adults Who Have Completed MAVERICK-HCM or EXPLORER-HCM

Who this might be right for
Hypertrophic CardiomyopathyObstructive Hypertrophic CardiomyopathyNon-obstructive Hypertrophic Cardiomyopathy
Bristol-Myers Squibb 314
Large-scale testing (Phase 3)Study completedNCT05174416
What this trial is testing

Evaluate the Efficacy and Safety of Mavacamten in Chinese Adults With Symptomatic Obstructive HCM

Who this might be right for
Obstructive Hypertrophic Cardiomyopathy
LianBio LLC 81
Large-scale testing (Phase 3)Study completedNCT03470545
What this trial is testing

Clinical Study to Evaluate Mavacamten (MYK-461) in Adults With Symptomatic Obstructive Hypertrophic Cardiomyopathy

Who this might be right for
Obstructive Hypertrophic Cardiomyopathy
MyoKardia, Inc. 251
Not applicableLooking for participantsNCT07541833
What this trial is testing

Effectiveness and Treatment Patterns of Mavacamten in Patients With Obstructive Hypertrophic Cardiomyopathy in Japan (MANAGE-HCM)

Who this might be right for
Cardiomyopathy
Bristol-Myers Squibb 36
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