Early research (Phase 1)Ended earlyNCT03938857What this trial is testingDOSE Trial of Opioid Sparing EffectWho this might be right forDexmedetomidineMechanical Ventilation ComplicationCritically Ill Duke University 30
Large-scale testing (Phase 3)UnknownNCT04082767What this trial is testingSedation Efficacy of Dexmedetomidine Versus Midazolam in Critically Ill Ventilated ChildrenWho this might be right forMechanically Ventilated, Critically Ill Children Douglas Fraser 120
Large-scale testing (Phase 3)Looking for participantsNCT04801589What this trial is testingGoal-Directed Sedation in Mechanically Ventilated Infants and ChildrenWho this might be right forDeliriumCritical IllnessSedation Complication+2 more Vanderbilt University Medical Center 372
Large-scale testing (Phase 3)UnknownNCT02989051What this trial is testingFluid Restriction Keeps Children DryWho this might be right forRespiratory InfectionFluid OverloadCritical Illness+1 more Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 34
Large-scale testing (Phase 3)Looking for participantsNCT05867472What this trial is testingAdvancing Brain Outcomes in Pediatric Critically Ill Patients Sedated With Volatile AnEsthestic AgentsWho this might be right forIntensive Care Units, PediatricAnesthetics, InhalationMechanically Ventilated, Critically Ill Children Sunnybrook Health Sciences Centre 60
Not applicableLooking for participantsNCT05969483What this trial is testingValidation of a Processed EEG Device for Monitoring Sedation in PICUWho this might be right forSedation Complication Azienda Ospedaliera di Padova 150
Not applicableUnknownNCT05054452What this trial is testingPredicting Fluid Responsiveness in Mechanically Ventilated Critically Ill Children Using Transthoracic EchocardiographyWho this might be right forFluid TherapyHemodynamicsHypovolemia+1 more Assistance Publique - Hôpitaux de Paris 76
Post-approval studies (Phase 4)Study completedNCT00959062What this trial is testingAdjunctive Clonidine in the Sedation of Mechanically Ventilated ChildrenWho this might be right forRespiration, ArtificialCritical IllnessConscious Sedation+1 more Hamilton Health Sciences Corporation 50
Large-scale testing (Phase 3)Study completedNCT00109395What this trial is testingLorazepam Sedation for Critically Ill ChildrenWho this might be right forCritical Illness The Emmes Company, LLC 179
Testing effectiveness (Phase 2)WithdrawnNCT03293927What this trial is testingPolypharmacy-related Adverse Events in Critically Ill ChildrenWho this might be right forDelirium Duke University