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Results for “Melas”

40 trials

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Showing 20 of 40 results

Not applicableStudy completedNCT03432871
What this trial is testing

Nicotinamide Riboside and Mitochondrial Biogenesis

Who this might be right for
Mitochondrial DiseasesMitochondrial MyopathiesProgressive External Ophthalmoplegia+4 more
Cambridge University Hospitals NHS Foundation Trust 13
Testing effectiveness (Phase 2)Active Not RecruitingNCT06402123
What this trial is testing

A Phase 2b Study of Zagociguat in Patients With MELAS

Who this might be right for
Mitochondrial Encephalopathy, Lactic Acidosis and Stroke-Like Episodes (MELAS Syndrome)
Tisento Therapeutics 43
Not applicableStudy completedNCT00004353
What this trial is testing

Study of the Metabolism of Pyruvate and Related Problems in Patients With Lactic Acidemia

Who this might be right for
Mitochondrial MyopathyMELAS SyndromeLactic Acidosis
National Center for Research Resources (NCRR) 35
Testing effectiveness (Phase 2)Study completedNCT02909400
What this trial is testing

The KHENERGY Study

Who this might be right for
Mitochondrial DiseasesMitochondrial MyopathiesMitochondrial Encephalomyopathies+2 more
Khondrion BV 20
Testing effectiveness (Phase 2)Study completedNCT00887562
What this trial is testing

Study of Idebenone in the Treatment of Mitochondrial Encephalopathy Lactic Acidosis & Stroke-like Episodes

Who this might be right for
MELAS Syndrome
Michio Hirano 27
Testing effectiveness (Phase 2)Looking for participantsNCT06644534
What this trial is testing

Assess TTI-0102 vs Placebo in MELAS Patients

Who this might be right for
MELAS SyndromeMitochondrial Encephalomyopathy, Lactic Acidosis and Stroke-like Episodes (MELAS)
Thiogenesis Therapeutics, Inc. 12
Large-scale testing (Phase 3)Ended earlyNCT04378075
What this trial is testing

Evaluate Efficacy and Safety of Vatiquinone for Treating Mitochondrial Disease in Participants With Refractory Epilepsy

Who this might be right for
Mitochondrial DiseasesDrug Resistant EpilepsyLeigh Disease+5 more
PTC Therapeutics 68
Not applicableLooking for participantsNCT01532791
What this trial is testing

Natural History Study - Mitochondrial Disease

Who this might be right for
MELAS or m.3243 A>G Mitochondrial DNA Mutation Carrier
Columbia University 300
Not applicableNo Longer AvailableNCT01370447
What this trial is testing

EPI-743 for Mitochondrial Respiratory Chain Diseases

Who this might be right for
Mitochondrial Diseases
PTC Therapeutics
Large-scale testing (Phase 3)Study completedNCT05218655
What this trial is testing

A Safety Study for Previously Treated Vatiquinone (PTC743) Participants With Inherited Mitochondrial Disease

Who this might be right for
Inherited Mitochondrial Disease
PTC Therapeutics 101
Testing effectiveness (Phase 2)Study completedNCT06051448
What this trial is testing

Promoting Resilience in Stress Management (PRISM) and Clinical-focused Narrative (CFN) Pilot in Adults With Primary Mitochondrial Disease (PMD).

Who this might be right for
Mitochondrial DiseasesMitochondrial MyopathiesMitochondrial Encephalomyopathies+2 more
Children's Hospital of Philadelphia 16
Very early researchStudy completedNCT01252979
What this trial is testing

Ketones & Mitochondrial Heteroplasmy

Who this might be right for
MELAS SyndromeMitochondrial Diseases
The University of Texas Health Science Center, Houston 13
Not applicableLooking for participantsNCT05554835
What this trial is testing

Global Registry and Natural History Study for Mitochondrial Disorders

Who this might be right for
Mitochondrial DiseasesKearns-Sayre SyndromeMIDD+15 more
LMU Klinikum 6,000
Not applicableStudy completedNCT06180421
What this trial is testing

Mitochondrial Video Assessment Source Material Study

Who this might be right for
PolG, Primary Mitochondrial Myopathy
The Emmes Company, LLC 28
Not applicableNot Yet RecruitingNCT06013397
What this trial is testing

Effectiveness of Ketogenic Diet in MELAS Syndrome

Who this might be right for
MELAS SyndromeKetogenic Dieting
Second Affiliated Hospital, School of Medicine, Zhejiang University 100
Testing effectiveness (Phase 2)Study completedNCT01603446
What this trial is testing

L-arginine Therapy on Endothelium-dependent Vasodilation & Mitochondrial Metabolism in MELAS Syndrome

Who this might be right for
MELAS Syndrome
The Hospital for Sick Children 7
Testing effectiveness (Phase 2)UnknownNCT00068913
What this trial is testing

Evaluating the Effectiveness of a Dichloroacetate in MELAS Syndrome

Who this might be right for
MELAS Syndrome
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) 35
Very early researchStudy completedNCT01339494
What this trial is testing

Nitric Oxide Production in MELAS Syndrome

Who this might be right for
MELAS Syndrome
Baylor College of Medicine 30
Early research (Phase 1)Study completedNCT03888716
What this trial is testing

A Phase Ia/Ib, SAD and MAD Study of of KL1333 in Healthy Subjects and Patients With Primary Mitochondrial Disease

Who this might be right for
Mitochondrial DiseasesMitochondrial Respiratory Chain DeficienciesMELAS Syndrome+1 more
Abliva AB 72
Not applicableLooking for participantsNCT01694940
What this trial is testing

North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)

Who this might be right for
Mitochondrial DisordersMitochondrial Genetic DisordersMitochondrial Diseases+2 more
Columbia University 1,000
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