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Results for “Mesothelin Expressing Neoplasms”

60 trials

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Showing 20 of 60 results

Early research (Phase 1)Looking for participantsNCT06623396
What this trial is testing

Mesothelin-Targeted CAR T-Cell Therapy in People With Esophagogastric Cancer

Who this might be right for
Mesothelin PositiveMesothelin-Expressing TumorsEsophageal Adenocarcinoma+5 more
Memorial Sloan Kettering Cancer Center 18
Early research (Phase 1)Ended earlyNCT04809766
What this trial is testing

Mesothelin-Specific T-Cells (FH-TCR-Tᴍsʟɴ) for the Treatment of Metastatic Pancreatic Ductal Adenocarcinoma

Who this might be right for
Metastatic Pancreatic Ductal AdenocarcinomaStage IV Pancreatic Cancer AJCC v8
Fred Hutchinson Cancer Center 9
Early research (Phase 1)Looking for participantsNCT05568680
What this trial is testing

SynKIR-110 for Mesothelin Expressing Ovarian Cancer, Cholangiocarcinoma or Mesothelioma

Who this might be right for
Ovarian CancerCholangiocarcinoma RecurrentMesothelioma, Malignant
Verismo Therapeutics 42
Early research (Phase 1)Study completedNCT01018784
What this trial is testing

MORAb-009 in Patients With Solid Tumor

Who this might be right for
CancerMesothelin-positive
Eisai Co., Ltd. 17
Testing effectiveness (Phase 2)UnknownNCT03030001
What this trial is testing

PD-1 Antibody Expressing CAR T Cells for Mesothelin Positive Advanced Malignancies

Who this might be right for
Solid Tumor, AdultAdvanced Cancer
Ningbo Cancer Hospital 40
Early research (Phase 1)Ended earlyNCT06523803
What this trial is testing

ZW171 in Participants With Advanced or Metastatic Mesothelin-expressing Cancers

Who this might be right for
Mesothelin-expressing Advanced Cancers
Zymeworks BC Inc. 32
Very early researchNot Yet RecruitingNCT07420010
What this trial is testing

An Open-label, Single-arm Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetic Profile, and Preliminary Efficacy of KT032 Cell Injection in Patients With Mesothelin-positive Advanced Solid Tumors.

Who this might be right for
Ovarian CancerMesotheliomaColon Cancer
Weijia Fang, MD 24
Testing effectiveness (Phase 2)Active Not RecruitingNCT03907852
What this trial is testing

Phase 1/2 Trial of Gavo-cel (TC-210) in Patients With Advanced Mesothelin-Expressing Cancer

Who this might be right for
MesotheliomaMesothelioma, MalignantMesothelioma; Pleura+8 more
TCR2 Therapeutics 57
Testing effectiveness (Phase 2)Ended earlyNCT04027946
What this trial is testing

LMB-100 Followed by Pembrolizumab in the Treatment of Adults With Mesothelin-Expressing Non-Squamous Non-Small Cell Lung Cancer (NSCLC)

Who this might be right for
Lung CancerNon-Small Cell Lung CancerAdenocarcinoma of Lung
National Cancer Institute (NCI) 6
Testing effectiveness (Phase 2)Study completedNCT03023722
What this trial is testing

Phase II Anetumab Ravtansine in Pre-treated Mesothelin-expressing Pancreatic Cancer

Who this might be right for
Pancreatic Cancer
Yale University 18
Very early researchUnknownNCT05373147
What this trial is testing

ΑPD1-MSLN-CAR T Cells for the Treatment of MSLN-positive Advanced Solid Tumors

Who this might be right for
Solid Tumor
Shanghai Mengchao Cancer Hospital 21
Very early researchEnded earlyNCT01413451
What this trial is testing

Amatuximab for High Mesothelin Cancers

Who this might be right for
Carcinoma, Pancreatic DuctalMesotheliomaOvarian Neoplasms+1 more
National Cancer Institute (NCI) 7
Early research (Phase 1)Looking for participantsNCT05403554
What this trial is testing

NI-1801 in Patients with Mesothelin Expressing Solid Cancers

Who this might be right for
Epithelial Ovarian CancerTriple Negative Breast CancerNon-squamous Non-small-cell Lung Cancer+2 more
Light Chain Bioscience - Novimmune SA 70
Early research (Phase 1)Not Yet RecruitingNCT05783089
What this trial is testing

MSLN-targeted CAR-T Cells in Solid Tumors.

Who this might be right for
Mesothelin-positive Advanced Malignant Solid Tumors
Cancer Institute and Hospital, Chinese Academy of Medical Sciences 87
Early research (Phase 1)Study completedNCT01521325
What this trial is testing

A Single-Dose Pilot Study of Radiolabeled Amatuximab (MORAb-009) in Mesothelin Over Expressing Cancers

Who this might be right for
MesotheliomaPancreatic CancerOvarian Cancer+1 more
Morphotek 6
Testing effectiveness (Phase 2)Looking for participantsNCT07083323
What this trial is testing

A Phase I/II Study of HY05350 in Mesothelin(MSLN)-Positive Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumor
Sichuan Huiyu Pharmaceutical Co., Ltd 262
Testing effectiveness (Phase 2)Active Not RecruitingNCT03126630
What this trial is testing

Pembrolizumab With or Without Anetumab Ravtansine in Treating Patients With Mesothelin-Positive Pleural Mesothelioma

Who this might be right for
Pleural Malignant Mesothelioma
National Cancer Institute (NCI) 49
Early research (Phase 1)UnknownNCT02580747
What this trial is testing

Treatment of Relapsed and/or Chemotherapy Refractory Advanced Malignancies by CART-meso

Who this might be right for
Malignant MesotheliomaPancreatic CancerOvarian Tumor+3 more
Chinese PLA General Hospital 20
Testing effectiveness (Phase 2)Ended earlyNCT05451849
What this trial is testing

A Phase 1/2 Trial of TC-510 In Patients With Advanced Mesothelin-Expressing Cancer

Who this might be right for
MesotheliomaMesotheliomas PleuralMesothelioma, Malignant+14 more
TCR2 Therapeutics 14
Early research (Phase 1)UnknownNCT06256055
What this trial is testing

Phase 1 Study of UCMYM802 Injection in Mesothelin-positive Advanced Malignant Solid Tumors

Who this might be right for
Malignant MesotheliomaColorectal CancerBile Duct Cancer+4 more
UTC Therapeutics Inc. 24
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