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Results for “Mesothelin-Expressing Tumors”

60 trials

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Showing 20 of 60 results

Early research (Phase 1)Study completedNCT02639091
What this trial is testing

Phase Ib Study of Anetumab Ravtansine in Combination With Pemetrexed and Cisplatin in Mesothelin-expressing Solid Tumors

Who this might be right for
Medical Oncology
Bayer 36
Not applicableLooking for participantsNCT01950572
What this trial is testing

Tissue Procurement and Natural History Study of Patients With Malignant Mesothelioma

Who this might be right for
ThymomaStomach NeoplasmsPancreatic Neoplasms+3 more
National Cancer Institute (NCI) 1,000
Early research (Phase 1)Study completedNCT02696642
What this trial is testing

Phase I Study of Anetumab Ravtansine in Hepatic or Renal Impairment

Who this might be right for
Neoplasms
Bayer 54
Early research (Phase 1)Ended earlyNCT04809766
What this trial is testing

Mesothelin-Specific T-Cells (FH-TCR-Tᴍsʟɴ) for the Treatment of Metastatic Pancreatic Ductal Adenocarcinoma

Who this might be right for
Metastatic Pancreatic Ductal AdenocarcinomaStage IV Pancreatic Cancer AJCC v8
Fred Hutchinson Cancer Center 9
Testing effectiveness (Phase 2)Active Not RecruitingNCT03126630
What this trial is testing

Pembrolizumab With or Without Anetumab Ravtansine in Treating Patients With Mesothelin-Positive Pleural Mesothelioma

Who this might be right for
Pleural Malignant Mesothelioma
National Cancer Institute (NCI) 49
Early research (Phase 1)Study completedNCT02824042
What this trial is testing

Thorough ECG (Electrocardiogram) and Drug Interaction Study With Anetumab Ravtansine and Itraconazole

Who this might be right for
Medical Oncology
Bayer 63
Early research (Phase 1)Looking for participantsNCT06756035
What this trial is testing

CT-95 in Advanced Cancers Associated With Mesothelin Expression

Who this might be right for
Mesothelin-Expressing TumorsEpithelial Ovarian CancerMalignant Pleural Mesothelioma, Advanced+8 more
Context Therapeutics Inc. 70
Very early researchUnknownNCT04489862
What this trial is testing

ΑPD1-MSLN-CAR T Cells for the Treatment of MSLN-positive Advanced Solid Tumors

Who this might be right for
Non-small-cell Lung CancerMesothelioma
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 10
Not applicableLooking for participantsNCT06717022
What this trial is testing

A Clinical Study of CHT102 in Mesothelin Positive Advanced Solid Tumors

Who this might be right for
Mesothelin Positive Tumors
Tianjin Medical University Cancer Institute and Hospital 24
Early research (Phase 1)WithdrawnNCT05375825
What this trial is testing

Phase I Evaluation of Immunotoxin LMB-100 Administered by Normothermic, Intrapleural Perfusion Following Cytoreductive Surgery in Participants With Pleural Mesotheliomas, or Pleural Effusions From Cancers Expressing Mesothelin

Who this might be right for
Malignant Pleural Mesotheliomas (Mpm)Malignant Pleural Effusions (Mpe)Epithelial Tumors, Malignant+2 more
National Cancer Institute (NCI)
Early research (Phase 1)Study completedNCT03054298
What this trial is testing

CAR T Cells in Mesothelin Expressing Cancers

Who this might be right for
Lung AdenocarcinomaOvarian CancerPeritoneal Carcinoma+3 more
University of Pennsylvania 65
Very early researchLooking for participantsNCT05166070
What this trial is testing

An Exploratory Clinical Study of RD133 in Subjects With Relapsed or Refractory MSLN-Positive Solid Tumors

Who this might be right for
Solid Tumor
The First Affiliated Hospital with Nanjing Medical University 24
Early research (Phase 1)UnknownNCT05089266
What this trial is testing

Study of αPD1-MSLN-CAR T Cells to Evaluate the Safety, Tolerability, and Effectiveness for Patients With MSLN-positive Advanced Solid Tumors

Who this might be right for
Colorectal Cancer
Shanghai Cell Therapy Group Co.,Ltd 30
Testing effectiveness (Phase 2)Active Not RecruitingNCT05451849
What this trial is testing

A Phase 1/2 Trial of TC-510 In Patients With Advanced Mesothelin-Expressing Cancer

Who this might be right for
MesotheliomaMesotheliomas PleuralMesothelioma, Malignant+14 more
TCR2 Therapeutics 6
Early research (Phase 1)Study completedNCT00325494
What this trial is testing

MORAb-009 in Subjects With Pancreatic Cancer, Mesothelioma, or Certain Types of Ovarian or Lung Cancer

Who this might be right for
Pancreatic CancerMesotheliomaOvarian Cancer+1 more
Morphotek 24
Early research (Phase 1)Ended earlyNCT02317419
What this trial is testing

RO6927005 Either As Monotherapy (Part A) or in Combination With Gemcitabine and Nab-Paclitaxel (Part B) to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Clinical Activity in Patients With Mesothelin-positive Metastatic and/or Locally Advanced Malignant Solid Tumors

Who this might be right for
Cancer
Hoffmann-La Roche 15
Early research (Phase 1)UnknownNCT02930993
What this trial is testing

Anti-mesothelin CAR T Cells for Patients With Recurrent or Metastatic Malignant Tumors

Who this might be right for
Mesothelin Positive Tumors
China Meitan General Hospital 20
Early research (Phase 1)UnknownNCT03747965
What this trial is testing

Study of PD-1 Gene-knocked Out Mesothelin-directed CAR-T Cells With the Conditioning of PC in Mesothelin Positive Multiple Solid Tumors

Who this might be right for
Solid Tumor, Adult
Chinese PLA General Hospital 10
Testing effectiveness (Phase 2)UnknownNCT05944185
What this trial is testing

Phase I/II Study of αPD1-MSLN-CAR T Cells in MSLN-positive Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumor
Shanghai Cell Therapy Group Co.,Ltd 42
Early research (Phase 1)Study completedNCT03102320
What this trial is testing

Phase 1b Multi-indication Study of Anetumab Ravtansine in Mesothelin Expressing Advanced Solid Tumors

Who this might be right for
Neoplasms
Bayer 173
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