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Results for “Mesothelin-expressing Advanced Cancers”

36 trials

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Showing 20 of 36 results

Early research (Phase 1)UnknownNCT05848999
What this trial is testing

UCLM802 (Anti-Mesothelin CAR-T) Cell Injection in Patients With Mesothelin-positive Advanced Malignant Solid Tumors

Who this might be right for
Mesothelin-positive Advanced Malignant Solid Tumors
Zhejiang University 87
Testing effectiveness (Phase 2)Active Not RecruitingNCT05451849
What this trial is testing

A Phase 1/2 Trial of TC-510 In Patients With Advanced Mesothelin-Expressing Cancer

Who this might be right for
MesotheliomaMesotheliomas PleuralMesothelioma, Malignant+14 more
TCR2 Therapeutics 6
Early research (Phase 1)Ended earlyNCT03455556
What this trial is testing

Anetumab Ravtansine and Atezolizumab in Treating Participants With Advanced Non-small Cell Lung Cancer

Who this might be right for
Mesothelin PositiveStage III Non-Small Cell Lung Cancer AJCC v7Stage IIIA Non-Small Cell Lung Cancer AJCC v7+2 more
Mayo Clinic 1
Very early researchUnknownNCT05373147
What this trial is testing

ΑPD1-MSLN-CAR T Cells for the Treatment of MSLN-positive Advanced Solid Tumors

Who this might be right for
Solid Tumor
Shanghai Mengchao Cancer Hospital 21
Early research (Phase 1)UnknownNCT05089266
What this trial is testing

Study of αPD1-MSLN-CAR T Cells to Evaluate the Safety, Tolerability, and Effectiveness for Patients With MSLN-positive Advanced Solid Tumors

Who this might be right for
Colorectal Cancer
Shanghai Cell Therapy Group Co.,Ltd 30
Early research (Phase 1)Active Not RecruitingNCT03816358
What this trial is testing

Testing the Combination of Anetumab Ravtansine With Either Nivolumab, Nivolumab and Ipilimumab, or Gemcitabine and Nivolumab in Advanced Pancreatic Cancer

Who this might be right for
Pancreatic AdenocarcinomaStage II Pancreatic Cancer AJCC v8Stage III Pancreatic Cancer AJCC v8+1 more
National Cancer Institute (NCI) 74
Testing effectiveness (Phase 2)Study completedNCT03023722
What this trial is testing

Phase II Anetumab Ravtansine in Pre-treated Mesothelin-expressing Pancreatic Cancer

Who this might be right for
Pancreatic Cancer
Yale University 18
Early research (Phase 1)Looking for participantsNCT06256055
What this trial is testing

Phase 1 Study of UCMYM802 Injection in Mesothelin-positive Advanced Malignant Solid Tumors

Who this might be right for
Malignant MesotheliomaColorectal CancerBile Duct Cancer+4 more
UTC Therapeutics Inc. 24
Very early researchUnknownNCT04503980
What this trial is testing

ΑPD1-MSLN-CAR T Cells for the Treatment of MSLN-positive Advanced Solid Tumors

Who this might be right for
Colorectal CancerOvarian Cancer
Shanghai Cell Therapy Group Co.,Ltd 10
Early research (Phase 1)Study completedNCT02696642
What this trial is testing

Phase I Study of Anetumab Ravtansine in Hepatic or Renal Impairment

Who this might be right for
Neoplasms
Bayer 54
Not applicableLooking for participantsNCT06717022
What this trial is testing

A Clinical Study of CHT102 in Mesothelin Positive Advanced Solid Tumors

Who this might be right for
Mesothelin Positive Tumors
Tianjin Medical University Cancer Institute and Hospital 24
Early research (Phase 1)WithdrawnNCT05531708
What this trial is testing

Exploratory Study of Novel MSLN CAR-T Cell Therapy in Patients With MSLN-positive Advanced Refractory Solid Tumors

Who this might be right for
Mesothelin-positive Advanced Refractory Solid Tumors
Shanghai Pudong Hospital
Early research (Phase 1)Looking for participantsNCT05568680
What this trial is testing

SynKIR-110 for Mesothelin Expressing Ovarian Cancer, Cholangiocarcinoma or Mesothelioma

Who this might be right for
Ovarian CancerCholangiocarcinoma RecurrentMesothelioma, Malignant
Verismo Therapeutics 42
Not applicableLooking for participantsNCT07010523
What this trial is testing

Anti-Mesothelin CAR-T Cell Injection in Patients With Mesothelin-positive Advanced Malignant Solid Tumors

Who this might be right for
Mesothelin-positive Advanced Malignant Solid Tumors
Zhejiang University 24
Early research (Phase 1)UnknownNCT05775666
What this trial is testing

UCLM802 (Anti-Mesothelin CAR-T) Cell Injection in Patients With Mesothelin-positive Advanced Malignant Solid Tumors

Who this might be right for
Solid Tumor
Peking University 87
Early research (Phase 1)Not Yet RecruitingNCT05783089
What this trial is testing

MSLN-targeted CAR-T Cells in Solid Tumors.

Who this might be right for
Mesothelin-positive Advanced Malignant Solid Tumors
Cancer Institute and Hospital, Chinese Academy of Medical Sciences 87
Early research (Phase 1)Ended earlyNCT02317419
What this trial is testing

RO6927005 Either As Monotherapy (Part A) or in Combination With Gemcitabine and Nab-Paclitaxel (Part B) to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Clinical Activity in Patients With Mesothelin-positive Metastatic and/or Locally Advanced Malignant Solid Tumors

Who this might be right for
Cancer
Hoffmann-La Roche 15
Early research (Phase 1)Ended earlyNCT05164666
What this trial is testing

TAK-103 in Adult With Solid Tumors

Who this might be right for
Solid Tumors
Takeda 2
Early research (Phase 1)Active Not RecruitingNCT02792114
What this trial is testing

T-Cell Therapy for Advanced Breast Cancer

Who this might be right for
Breast CancerMetastatic HER2-negative Breast
Memorial Sloan Kettering Cancer Center 186
Early research (Phase 1)UnknownNCT02580747
What this trial is testing

Treatment of Relapsed and/or Chemotherapy Refractory Advanced Malignancies by CART-meso

Who this might be right for
Malignant MesotheliomaPancreatic CancerOvarian Tumor+3 more
Chinese PLA General Hospital 20
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