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Results for “Mesothelin-expressing Advanced Cancers”

37 trials

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Showing 20 of 37 results

Early research (Phase 1)Study completedNCT02696642
What this trial is testing

Phase I Study of Anetumab Ravtansine in Hepatic or Renal Impairment

Who this might be right for
Neoplasms
Bayer 54
Early research (Phase 1)Study completedNCT02824042
What this trial is testing

Thorough ECG (Electrocardiogram) and Drug Interaction Study With Anetumab Ravtansine and Itraconazole

Who this might be right for
Medical Oncology
Bayer 63
Early research (Phase 1)Looking for participantsNCT06756035
What this trial is testing

CT-95 in Advanced Cancers Associated With Mesothelin Expression

Who this might be right for
Mesothelin-Expressing TumorsEpithelial Ovarian CancerMalignant Pleural Mesothelioma, Advanced+8 more
Context Therapeutics Inc. 70
Very early researchUnknownNCT04489862
What this trial is testing

ΑPD1-MSLN-CAR T Cells for the Treatment of MSLN-positive Advanced Solid Tumors

Who this might be right for
Non-small-cell Lung CancerMesothelioma
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 10
Not applicableLooking for participantsNCT06717022
What this trial is testing

A Clinical Study of CHT102 in Mesothelin Positive Advanced Solid Tumors

Who this might be right for
Mesothelin Positive Tumors
Tianjin Medical University Cancer Institute and Hospital 24
Early research (Phase 1)UnknownNCT05089266
What this trial is testing

Study of αPD1-MSLN-CAR T Cells to Evaluate the Safety, Tolerability, and Effectiveness for Patients With MSLN-positive Advanced Solid Tumors

Who this might be right for
Colorectal Cancer
Shanghai Cell Therapy Group Co.,Ltd 30
Testing effectiveness (Phase 2)Active Not RecruitingNCT05451849
What this trial is testing

A Phase 1/2 Trial of TC-510 In Patients With Advanced Mesothelin-Expressing Cancer

Who this might be right for
MesotheliomaMesotheliomas PleuralMesothelioma, Malignant+14 more
TCR2 Therapeutics 6
Early research (Phase 1)Study completedNCT00325494
What this trial is testing

MORAb-009 in Subjects With Pancreatic Cancer, Mesothelioma, or Certain Types of Ovarian or Lung Cancer

Who this might be right for
Pancreatic CancerMesotheliomaOvarian Cancer+1 more
Morphotek 24
Early research (Phase 1)Ended earlyNCT02317419
What this trial is testing

RO6927005 Either As Monotherapy (Part A) or in Combination With Gemcitabine and Nab-Paclitaxel (Part B) to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Clinical Activity in Patients With Mesothelin-positive Metastatic and/or Locally Advanced Malignant Solid Tumors

Who this might be right for
Cancer
Hoffmann-La Roche 15
Testing effectiveness (Phase 2)UnknownNCT05944185
What this trial is testing

Phase I/II Study of αPD1-MSLN-CAR T Cells in MSLN-positive Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumor
Shanghai Cell Therapy Group Co.,Ltd 42
Early research (Phase 1)Study completedNCT03102320
What this trial is testing

Phase 1b Multi-indication Study of Anetumab Ravtansine in Mesothelin Expressing Advanced Solid Tumors

Who this might be right for
Neoplasms
Bayer 173
Early research (Phase 1)Looking for participantsNCT05568680
What this trial is testing

SynKIR-110 for Mesothelin Expressing Ovarian Cancer, Cholangiocarcinoma or Mesothelioma

Who this might be right for
Ovarian CancerCholangiocarcinoma RecurrentMesothelioma, Malignant
Verismo Therapeutics 42
Early research (Phase 1)Looking for participantsNCT06760364
What this trial is testing

A Clinical Study of CHT102 in MSLN-Positive Advanced Pancreatic Cancer

Who this might be right for
Advanced Pancreatic Cancers
Tianjin Medical University Cancer Institute and Hospital 21
Testing effectiveness (Phase 2)UnknownNCT03615313
What this trial is testing

PD-1 Antibody Expressing mesoCAR-T Cells for Mesothelin Positive Advanced Solid Tumor

Who this might be right for
Advanced Solid Tumor
Shanghai Cell Therapy Research Institute 50
Early research (Phase 1)UnknownNCT02580747
What this trial is testing

Treatment of Relapsed and/or Chemotherapy Refractory Advanced Malignancies by CART-meso

Who this might be right for
Malignant MesotheliomaPancreatic CancerOvarian Tumor+3 more
Chinese PLA General Hospital 20
Not applicableLooking for participantsNCT07010523
What this trial is testing

Anti-Mesothelin CAR-T Cell Injection in Patients With Mesothelin-positive Advanced Malignant Solid Tumors

Who this might be right for
Mesothelin-positive Advanced Malignant Solid Tumors
Zhejiang University 24
Early research (Phase 1)Not Yet RecruitingNCT05783089
What this trial is testing

MSLN-targeted CAR-T Cells in Solid Tumors.

Who this might be right for
Mesothelin-positive Advanced Malignant Solid Tumors
Cancer Institute and Hospital, Chinese Academy of Medical Sciences 87
Early research (Phase 1)UnknownNCT06256055
What this trial is testing

Phase 1 Study of UCMYM802 Injection in Mesothelin-positive Advanced Malignant Solid Tumors

Who this might be right for
Malignant MesotheliomaColorectal CancerBile Duct Cancer+4 more
UTC Therapeutics Inc. 24
Early research (Phase 1)Study completedNCT04034238
What this trial is testing

Mesothelin-Targeted Immunotoxin LMB-100 in Combination With Tofacitinib in Persons With Previously Treated Pancreatic Adenocarcinoma, Cholangiocarcinoma and Other Mesothelin Expressing Solid Tumors

Who this might be right for
Neoplasms With Mesothelin ExpressionEpithelioid MesotheliomaCholangiocarcinoma, Extrahepatic+1 more
National Cancer Institute (NCI) 19
Early research (Phase 1)Active Not RecruitingNCT02792114
What this trial is testing

T-Cell Therapy for Advanced Breast Cancer

Who this might be right for
Breast CancerMetastatic HER2-negative Breast
Memorial Sloan Kettering Cancer Center 186
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