Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Metastatic Colorectal Cancer Patients With KRAS Mutated Tumors”

44 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 44 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT06106308
What this trial is testing

Study of Onvansertib in Combination With FOLFIRI and Bevacizumab or FOLFOX and Bevacizumab Versus FOLFIRI and Bevacizumab or FOLFOX and Bevacizumab for First-Line Treatment of Metastatic Colorectal Cancer in Adult Participants With a KRAS or NRAS Mutation

Who this might be right for
Metastatic Colorectal CancerCRCKRAS/NRAS Mutation
Cardiff Oncology 110
Testing effectiveness (Phase 2)Looking for participantsNCT06445062
What this trial is testing

Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors

Who this might be right for
Colorectal CancerCRCPancreatic Ductal Adenocarcinoma+3 more
Revolution Medicines, Inc. 1,130
Testing effectiveness (Phase 2)Ended earlyNCT01562899
What this trial is testing

MEK162 and AMG 479 in Patients With Selected Solid Tumors

Who this might be right for
Metastatic Pancreatic AdenocarcinomaBRAF Mutated Melanoma
Pfizer 77
Not applicableStudy completedNCT02751177
What this trial is testing

Detection of KRAS, NRAS et BRAF Mutations in Plasma Circulating DNA From Patients With Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer Metastatic
Institut de Cancérologie de Lorraine 236
Testing effectiveness (Phase 2)Active Not RecruitingNCT04117945
What this trial is testing

Regorafenib, With Cetuximab or Panitumumab, for the Treatment of Unresectable, Locally Advanced, or Metastatic Colorectal Cancer

Who this might be right for
BRAF V600E NegativeKRAS Gene Mutation NegativeLocally Advanced Unresectable Colorectal Adenocarcinoma+10 more
Academic and Community Cancer Research United 22
Large-scale testing (Phase 3)Study completedNCT02394795
What this trial is testing

Panitumumab and RAS, Diagnostically-useful Gene Mutation for mCRC

Who this might be right for
Colorectal Cancer
Takeda 823
Testing effectiveness (Phase 2)Active Not RecruitingNCT03785249
What this trial is testing

Phase 1/2 Study of MRTX849 in Patients With Cancer Having a KRAS G12C Mutation KRYSTAL-1

Who this might be right for
Advanced CancerMetastatic CancerMalignant Neoplastic Disease
Mirati Therapeutics Inc. 731
Large-scale testing (Phase 3)WithdrawnNCT01646554
What this trial is testing

Efficacy of FOLFOX Versus FOLFOX Plus Aflibercept in K-ras Mutant Patients With Resectable Liver Metastases

Who this might be right for
Colorectal Cancer MetastaticLiver MetastasesKRAS Mutated Colorectal Cancer
European Organisation for Research and Treatment of Cancer - EORTC
Not applicableStudy completedNCT03698253
What this trial is testing

Metastatic Colorectal Cancer Treated With Regorafenib and FOLFIRI

Who this might be right for
Colorectal Cancer
Kaohsiung Medical University Chung-Ho Memorial Hospital 41
Testing effectiveness (Phase 2)UnknownNCT03457896
What this trial is testing

Study of Neratinib +Trastuzumab or Neratinib + Cetuximab in Patients With KRAS/NRAS/BRAF/PIK3CA Wild-Type Metastatic Colorectal Cancer by HER2 Status

Who this might be right for
Metastatic Colorectal Cancer
NSABP Foundation Inc 35
Early research (Phase 1)Study completedNCT02906059
What this trial is testing

Study of Irinotecan and AZD1775, a Selective Wee 1 Inhibitor, in RAS or BRAF Mutated, Second-line Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
NYU Langone Health 7
Testing effectiveness (Phase 2)Active Not RecruitingNCT04699188
What this trial is testing

Study of JDQ443 in Patients With Advanced Solid Tumors Harboring the KRAS G12C Mutation

Who this might be right for
KRAS G12C Mutant Solid TumorsCarcinoma, Non-Small-Cell LungCarcinoma, Colorectal+7 more
Novartis Pharmaceuticals 344
Early research (Phase 1)Ended earlyNCT04627142
What this trial is testing

Test Different Doses of BI 1701963 in Combination With Irinotecan in People With Advanced Bowel Cancer With Kirsten Rat Sarcoma Viral Oncogene Homologue (KRAS) Mutation

Who this might be right for
Metastatic Colorectal Cancer (CRC)
Boehringer Ingelheim 15
Testing effectiveness (Phase 2)Active Not RecruitingNCT03087071
What this trial is testing

Panitumumab With or Without Trametinib in Treating Patients With Stage IV Colorectal Cancer

Who this might be right for
EGFR NP_005219.2:p.S492RKRAS Gene MutationMAP2K1 Gene Mutation+5 more
M.D. Anderson Cancer Center 59
Early research (Phase 1)Ended earlyNCT04975256
What this trial is testing

Adagrasib in Combination With BI 1701963 in Patients With Cancer (KRYSTAL 14)

Who this might be right for
Advanced CancerMetastatic CancerMalignant Neoplasm of Colon+2 more
Mirati Therapeutics Inc. 7
Not applicableStudy completedNCT01811108
What this trial is testing

Assessment of Clinical Practice Administration of Chemotherapy and Anti-angiogenic Agent (Bevacizumab) in Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
Hellenic Oncology Research Group 670
Testing effectiveness (Phase 2)Temporarily pausedNCT05200442
What this trial is testing

VS-6766 and Cetuximab in Patients With Advanced Colorectal Cancer

Who this might be right for
Colorectal CancerColorectal AdenocarcinomaColorectal Cancer Metastatic+2 more
University of Chicago 53
Testing effectiveness (Phase 2)Study completedNCT01387880
What this trial is testing

Irinotecan, Cetuximab and Everolimus to Patients With Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
Herlev Hospital 100
Early research (Phase 1)Ended earlyNCT05631574
What this trial is testing

Study of Covalent Menin Inhibitor BMF-219 in Adult Patients With KRAS Driven Non-Small Cell Lung Cancer, Pancreatic Cancer, and Colorectal Cancer

Who this might be right for
Non Small Cell Lung CancerPancreatic CancerColorectal Cancer+14 more
Biomea Fusion Inc. 13
Testing effectiveness (Phase 2)Ended earlyNCT02316496
What this trial is testing

Rechallenge of Cetuximab Combined With Irinotecan as Third-line Chemotherapy in Patients With Metastatic Colorectal Cancer - Phase II Study

Who this might be right for
Colorectal Cancer Metastatic
GERCOR - Multidisciplinary Oncology Cooperative Group 2
Next Page