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Results for “Metastatic Gastroesophageal Adenocarcinoma”

301 trials

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Showing 20 of 301 results

Large-scale testing (Phase 3)UnknownNCT02409199
What this trial is testing

Apatinib Versus Docetaxol Patients With Advanced Gastric Cancer

Who this might be right for
Gastric Carcinoma
Shanghai Zhongshan Hospital 66
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07243938
What this trial is testing

Phase II Basket Trial: Zanidatamab Plus Tislelizumab in HER2-Positive GI Tumors (UNION-HER2-BASKET)

Who this might be right for
Locally Advanced Rectal Cancer (LARC)Locally Advanced Gastric/Gastroesophageal Junction AdenocarcinomaMetastatic Colorectal Cancer (mCRC)+1 more
Tao Zhang 70
Testing effectiveness (Phase 2)Looking for participantsNCT05671822
What this trial is testing

Ph1b/2 Study of the Safety and Efficacy of SHR-A1811 Combinations in Advanced HER2 Expression Gastric Cancer

Who this might be right for
HER2 Expression Gastric Cancer/Gastroesophageal Junction Adenocarcinoma
Suzhou Suncadia Biopharmaceuticals Co., Ltd. 258
Testing effectiveness (Phase 2)Looking for participantsNCT07176312
What this trial is testing

Zanidatamab in Combination With Pembrolizumab and Chemotherapy in HER2 and PD-L1 Positive Metastatic Gastroesophageal Adenocarcinoma (GEA) Patients

Who this might be right for
Gastroesophageal AdenocarcinomaFirst Line TherapyHER2 + Gastric Cancer+2 more
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest 80
Testing effectiveness (Phase 2)WithdrawnNCT03592407
What this trial is testing

Epacadostat and Pembrolizumab Before Surgery in Treating Participants With Stage II-III Esophageal or Gastroesophageal Cancer

Who this might be right for
Esophageal Squamous Cell CarcinomaEsophageal AdenocarcinomaGastroesophageal Junction Adenocarcinoma
City of Hope Medical Center
Not applicableLooking for participantsNCT06846996
What this trial is testing

Real-world Effectiveness and Safety of Trastuzumab Deruxtecan in Patients With Locally Advanced or Metastatic HER2-positive Gastric or Gastroesophageal Junction Adenocarcinoma in China

Who this might be right for
HER2-positive Gastric CancerHER2-positive Gastroesophageal Junction
Daiichi Sankyo 260
Large-scale testing (Phase 3)Looking for participantsNCT07043400
What this trial is testing

Investigate Tislelizumab Administered as Subcutaneous Injection Versus Intravenous Infusion Plus Chemotherapy in Patients With Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma

Who this might be right for
Metastatic Gastric AdenocarcinomaGastroesophageal Junction Adenocarcinoma
BeOne Medicines 351
Testing effectiveness (Phase 2)Looking for participantsNCT05640609
What this trial is testing

Capeox Regimen Combined With Sintilimab and Bevacizumab for Gastric Cancer

Who this might be right for
Stomach Neoplasm
West China Hospital 57
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06586294
What this trial is testing

Anti-PD-1 and LAG-3 Bispecific Antibody(AK129) Combined With Chemotherapy With or Without Cadonilimab in the First-line Treatment of Unresectable Locally Advanced or Metastatic G/ GEJ Adenocarcinoma

Who this might be right for
Gastric AdenocarcinomaGastroesophageal Junction Adenocarcinoma
Akeso 294
Testing effectiveness (Phase 2)Study completedNCT01611857
What this trial is testing

Phase I/II Trial of Tivantinib With FOLFOX for the Treatment of Advanced Solid Tumors and Previously Untreated Metastatic Adenocarcinoma of the Distal Esophagus, Gastroesophageal Junction or Stomach

Who this might be right for
Malignant Solid TumourGastroesophageal Cancer
SCRI Development Innovations, LLC 49
Testing effectiveness (Phase 2)Looking for participantsNCT06962137
What this trial is testing

Phase II RAINSPOT: Zolbetuximab-Paclitaxel-Ramucirumab for CLDN18.2 Positive Gastro-esophageal Cancer

Who this might be right for
Gastric Cancer Adenocarcinoma MetastaticGastric Adenocarcinoma and Gastroesophageal Junction Adenocarcinoma
Universitaire Ziekenhuizen KU Leuven 100
Large-scale testing (Phase 3)Study completedNCT00680901
What this trial is testing

LOGiC - Lapatinib Optimization Study in ErbB2 (HER2) Positive Gastric Cancer: A Phase III Global, Blinded Study Designed to Evaluate Clinical Endpoints and Safety of Chemotherapy Plus Lapatinib

Who this might be right for
Neoplasms, Gastrointestinal Tract
Novartis Pharmaceuticals 545
Early research (Phase 1)Study completedNCT04805307
What this trial is testing

Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy, Phase 1 Study of CMG901

Who this might be right for
Advanced Solid TumorGastric Cancer(Including Gastroesophageal Junction Adenocarcinoma)Pancreatic Cancer
Keymed Biosciences Co.Ltd 176
Testing effectiveness (Phase 2)Study completedNCT00940225
What this trial is testing

Study of Cabozantinib (XL184) in Adults With Advanced Malignancies

Who this might be right for
Solid TumorsCancer
Exelixis 730
Testing effectiveness (Phase 2)Study completedNCT00780494
What this trial is testing

Ph II of Capecitabine, Carboplatin & Bevacizumab for Gastroesophageal Junction & Gastric Carcinoma

Who this might be right for
Stomach CancerGastric (Stomach) CancerNeoplasm of Cardioesophageal Junction+1 more
Stanford University 35
Large-scale testing (Phase 3)Study completedNCT03675737
What this trial is testing

Pembrolizumab (MK-3475) Plus Chemotherapy Versus Placebo Plus Chemotherapy in Participants Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma (MK-3475-859/KEYNOTE-859)

Who this might be right for
Stomach Neoplasms
Merck Sharp & Dohme LLC 1,579
Testing effectiveness (Phase 2)Study completedNCT02340975
What this trial is testing

A Phase 1b/2 Study of MEDI4736 With Tremelimumab, MEDI4736 or Tremelimumab Monotherapy in Gastric or GEJ Adenocarcinoma

Who this might be right for
Gastric or Gastroesophageal Junction Adenocarcinoma
MedImmune LLC 114
Testing effectiveness (Phase 2)Looking for participantsNCT06767800
What this trial is testing

A Clinical Trial Evaluating TQB2102 for Injection in Combination With Behmosubaisumab/Payamprolizumab With or Without Chemotherapy in Unresectable Locally Advanced, Recurrent, or Metastatic Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Gastroesophageal Adenocarcinoma

Who this might be right for
Gastroesophageal Adenocarcinoma
Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd. 204
Not applicableUnknownNCT04915807
What this trial is testing

Real-world Data (RWD) of Ramucirumab Plus Paclitaxel

Who this might be right for
Gastric CancerGastroesophageal Junction Adenocarcinoma
Hallym University Medical Center 222
Testing effectiveness (Phase 2)Looking for participantsNCT05086692
What this trial is testing

A Beta-only IL-2 ImmunoTherapY Study

Who this might be right for
Advanced Solid TumorUnresectable Solid TumorClear Cell Renal Cell Carcinoma+34 more
Medicenna Therapeutics, Inc. 115
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