Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Metformin Response”

53 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 53 results

Testing effectiveness (Phase 2)Study completedNCT03772964
What this trial is testing

Effects of Metformin in a Non-Diabetic Patient Population

Who this might be right for
Inflammatory Response
Brian Zuckerbraun 32
Early research (Phase 1)UnknownNCT02149459
What this trial is testing

Treatment of Recurrent Brain Tumors: Metabolic Manipulation Combined With Radiotherapy

Who this might be right for
Brain Neoplasms
Sheba Medical Center 18
Testing effectiveness (Phase 2)UnknownNCT01566799
What this trial is testing

Metformin Plus Neoadjuvant Chemotherapy in Breast Cancer

Who this might be right for
Locally Advanced Malignant Neoplasm
Instituto Nacional de Cancerologia de Mexico 60
Testing effectiveness (Phase 2)Ended earlyNCT02495103
What this trial is testing

Vandetanib in Combination With Metformin in People With HLRCC or SDH-Associated Kidney Cancer or Sporadic Papillary Renal Cell Carcinoma

Who this might be right for
Renal Cell CarcinomaHereditary LeiomyomatosisRenal Cell Cancer
National Cancer Institute (NCI) 7
Post-approval studies (Phase 4)Looking for participantsNCT06829238
What this trial is testing

Assessment of Metformin for Restoration of Immune Homeostasis in HIV+ and HIV- Individuals With a History of Injection Drug Use

Who this might be right for
Systemic InflammationImmune DysregulationInjection Drug Use+1 more
University of Alabama at Birmingham 100
Post-approval studies (Phase 4)WithdrawnNCT04741204
What this trial is testing

Metformin Use to Reduce Disparities in Newly Diagnosed Breast Cancer

Who this might be right for
Breast Cancer StageInsulin ResistanceRacial Bias
Woman's
Testing effectiveness (Phase 2)Looking for participantsNCT06687876
What this trial is testing

Metformin as a Metabolic Intervention in Oesophageal Adenocarcinomas to Improve Response to Neoadjuvant Chemoradiotherapy

Who this might be right for
Oesophageal AdenocarcinomaTumor Microenvironment
Amsterdam UMC, location VUmc 14
Not applicableStudy completedNCT05628584
What this trial is testing

High FODMAP Diet With Metformin in preDM

Who this might be right for
PreDiabetesImpaired Glucose Tolerance
Elaine Chow 26
Testing effectiveness (Phase 2)Study completedNCT05900284
What this trial is testing

Safety and Feasibility of Metformin for Sepsis Induced AKI

Who this might be right for
SepsisSeptic ShockAcute Kidney Injury+1 more
Hernando Gomez 80
Post-approval studies (Phase 4)UnknownNCT02097342
What this trial is testing

Effect of Linagliptin on Insulin Sensitivity and Pancreatic Beta Cell Function in Patients With Type 2 Diabetes Mellitus

Who this might be right for
Type 2 Diabetes MellitusInsulin Sensitivity/Resistance
Post Graduate Institute of Medical Education and Research, Chandigarh 30
Not applicableStudy completedNCT07513480
What this trial is testing

Pretreatment With CPA-EE, Metformin and Myoinositol in PCOS With High AMH

Who this might be right for
PCOS
Mst.Sumyara Khatun 68
Large-scale testing (Phase 3)UnknownNCT05979038
What this trial is testing

Clinical Evaluation of the Effect of Metformin in Sepsis

Who this might be right for
Sepsis
German University in Cairo 110
Post-approval studies (Phase 4)Study completedNCT02483299
What this trial is testing

Liraglutide as Add on Therapy on Metformin in Women With Polycystic Ovary Syndrome

Who this might be right for
PCOSObesity
University Medical Centre Ljubljana 40
Large-scale testing (Phase 3)Study completedNCT03610412
What this trial is testing

Cinnamomum Cassia Effect on IGF1 and Metabolic Control in Patients With DM2 Without Glycemic Control Metformin Treated

Who this might be right for
Diabetes Mellitus, Type 2
Coordinación de Investigación en Salud, Mexico 28
Early research (Phase 1)Ended earlyNCT01816659
What this trial is testing

An Open-Labeled Pilot Study of Biomarker Response Following Short-Term Exposure to Metformin

Who this might be right for
Colorectal Carcinoma
M.D. Anderson Cancer Center 3
Post-approval studies (Phase 4)Study completedNCT01911468
What this trial is testing

Polycystic Ovary Syndrome and Liraglutide as Add-on Therapy on Metformin

Who this might be right for
PCOSObesity
University Medical Centre Ljubljana 36
Post-approval studies (Phase 4)Ended earlyNCT01208740
What this trial is testing

Metformin in Patients With PCOS and Predictors of Poor Ovarian Response Ongoing In-vitro Fertilization

Who this might be right for
InfertilityPCOSPrognosis for Poor Response
University Magna Graecia 88
Post-approval studies (Phase 4)Study completedNCT00187681
What this trial is testing

Organic Cation Transporter 1 (OCT1), on Response to Metformin in Healthy Subjects

Who this might be right for
Other Conditions That May Be A Focus of Clinical Attention
University of California, San Francisco 20
Testing effectiveness (Phase 2)Study completedNCT03053544
What this trial is testing

Metformin With Neoadjuvant Chemoradiation to Improve Pathologic Responses in Rectal Cancer

Who this might be right for
Rectal Neoplasm Carcinoma in Situ Adenocarcinoma
Sunnybrook Health Sciences Centre 15
Early research (Phase 1)Study completedNCT03996538
What this trial is testing

Vaccination Efficacy With Metformin in Older Adults

Who this might be right for
AgingAge-Related ImmunodeficiencyVaccine Response Impaired
UConn Health 26
Next Page