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Results for “Microsatellite Instability”

157 trials

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Showing 20 of 157 results

Not applicableNot Yet RecruitingNCT07645742
What this trial is testing

Pilot Study of Intermittent Fasting With Immune Checkpoint Inhibitors

Who this might be right for
Cancer (Advanced Stage)
West Virginia University 90
Testing effectiveness (Phase 2)Looking for participantsNCT03667170
What this trial is testing

KN035 for dMMR/MSI-H Advanced Solid Tumors

Who this might be right for
Solid Tumor
3D Medicines (Sichuan) Co., Ltd. 200
Testing effectiveness (Phase 2)UnknownNCT04411524
What this trial is testing

The Combination of Immunotherapy and Neoadjuvant Chemoradiotherapy in MSI-H Locally Advanced Rectal Cancer

Who this might be right for
Locally Advanced Rectal Cancer
Fudan University 50
Testing effectiveness (Phase 2)Active Not RecruitingNCT03935893
What this trial is testing

Adoptive Transfer of Tumor Infiltrating Lymphocytes for Advanced Solid Cancers

Who this might be right for
Gastric CancerColorectal CancerPancreatic Cancer+7 more
Udai Kammula 20
Testing effectiveness (Phase 2)WithdrawnNCT04001101
What this trial is testing

Anti-PD-1 +/- RT for MSI-H Solid Tumors

Who this might be right for
Microsatellite Instability HighMismatch Repair DeficiencyColorectal Cancer
University of Colorado, Denver
Testing effectiveness (Phase 2)Active Not RecruitingNCT07523763
What this trial is testing

Neoadjuvant Low-dose Immunotherapy in Locally Advanced MMR-deficient Colorectal Cancer

Who this might be right for
Colorectal Cancer (MSI-H)Colorectal Cancer (CRC)
Blokhin's Russian Cancer Research Center 30
Testing effectiveness (Phase 2)UnknownNCT04118933
What this trial is testing

PD-1 Antibody JS001 in MSI-H Advanced or Recurrent Colorectal Cancer

Who this might be right for
Colorectal Cancer
Xu jianmin 40
Not applicableStudy completedNCT03774862
What this trial is testing

Clinicopathological Importance of Colorectal Medullary Carcinoma: Retrospective Cohort Study

Who this might be right for
Colorectal Medullary Carcinoma
V.K.V. American Hospital, Istanbul 13
Not applicableUnknownNCT00232960
What this trial is testing

Postoperative Radiotherapy According to Molecular Analysis of Surgical Margins of Oral and Oropharyngeal SCC

Who this might be right for
Oral CancerOropharynx Cancer
Gustave Roussy, Cancer Campus, Grand Paris 310
Testing effectiveness (Phase 2)Looking for participantsNCT04114136
What this trial is testing

Anti-PD-1 mAb Plus Metabolic Modulator in Solid Tumor Malignancies

Who this might be right for
MelanomaNSCLCHepatocellular Carcinoma+5 more
Dan Zandberg 72
Early research (Phase 1)Ended earlyNCT05909995
What this trial is testing

Interventional Study of INCB 99280 With Ipilimumab in Participants With Select Solid Tumors

Who this might be right for
MelanomaHepatocellular Carcinoma (HCC)Renal Cell Carcinoma (RCC)+3 more
Incyte Corporation 8
Not applicableUnknownNCT04191226
What this trial is testing

Genetic Mutation in Recurrent Cervical Cancer

Who this might be right for
Recurrent Cervical CancerNucleotide VariantCopy Number Variation+6 more
Lei Li 300
Testing effectiveness (Phase 2)Looking for participantsNCT06002789
What this trial is testing

Safety and Efficacy of PD-1 ± mFOLFOX6 Neoadjuvant Therapy in Local Advanced sMPCC

Who this might be right for
Multiple CancerColorectal Cancer
Sixth Affiliated Hospital, Sun Yat-sen University 17
Large-scale testing (Phase 3)Active Not RecruitingNCT05890742
What this trial is testing

A Clinical Trial Evaluating the Efficacy and Safety of IBI310 in Combination With Sintilimab, for Neoadjuvant Treatment of MSI-H/dMMR Resectable Colon Cancer

Who this might be right for
MSI-H
Innovent Biologics (Suzhou) Co. Ltd. 453
Testing effectiveness (Phase 2)Active Not RecruitingNCT02628067
What this trial is testing

Study of Pembrolizumab (MK-3475) in Participants With Advanced Solid Tumors (MK-3475-158/KEYNOTE-158)

Who this might be right for
Advanced CancerAnal CarcinomaAnal Cancer+22 more
Merck Sharp & Dohme LLC 1,609
Not applicableEnded earlyNCT04106167
What this trial is testing

Long-term, Non-interventional, Observational Study Following Treatment With Fate Therapeutics FT500 Cellular Immunotherapy

Who this might be right for
Advanced Solid TumorLymphomaGastric Cancer+15 more
Fate Therapeutics 20
Large-scale testing (Phase 3)Active Not RecruitingNCT02997228
What this trial is testing

Testing the Addition of Atezolizumab to Combination Chemotherapy or Atezolizumab Alone for Metastatic Colon or Rectal Cancer, the COMMIT Study

Who this might be right for
Metastatic Colorectal AdenocarcinomaStage IV Colorectal Cancer AJCC v7
National Cancer Institute (NCI) 120
Large-scale testing (Phase 3)Looking for participantsNCT06686576
What this trial is testing

Neoadjuvant QL1706 in Participants With Untreated dMMR/MSI-H Resectable Colon Cancer

Who this might be right for
Colon Cancer
Qilu Pharmaceutical Co., Ltd. 363
Not applicableStudy completedNCT05162248
What this trial is testing

Microsatellite Instability in Colorectal Cancers

Who this might be right for
Colorectal CancerColorectal CarcinomaMicrosatellite Instability High+2 more
Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey 231
Post-approval studies (Phase 4)Not Yet RecruitingNCT06897527
What this trial is testing

Evaluate the Safety of Dostarlimab in Adult Participants in India With Recurrent or Advanced Endometrial Cancer (EC)

Who this might be right for
Neoplasms, Endometrial
GlaxoSmithKline 100
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