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Results for “Microsatellite Instability”

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Showing 20 of 0 results

Large-scale testing (Phase 3)Active Not RecruitingNCT04008030
What this trial is testing

Nivolumab, Nivolumab Plus Ipilimumab, or Investigator's Choice Chemotherapy for the Treatment of Participants With Deficient Mismatch Repair (dMMR)/Microsatellite Instability High (MSI-H) Metastatic Colorectal Cancer (mCRC)

Who this might be right for
Metastatic Colorectal Cancer
Bristol-Myers Squibb 839
Not applicableUnknownNCT06043232
What this trial is testing

MMR/MSI Phenotypes in Prediction of Tumor Vaccine Benefit for Gliomas

Who this might be right for
Glioma
Huashan Hospital 360
Testing effectiveness (Phase 2)UnknownNCT04695470
What this trial is testing

Phase II Trial of Fruquintinib With Sintilimab in Treating Selected Refractory Metastatic Colorectal Cancer Patients

Who this might be right for
Colorectal Cancer
Aiping Zhou 70
Testing effectiveness (Phase 2)Looking for participantsNCT06059495
What this trial is testing

DEWI: Watch-and-Wait With Dostarlimab in Localized dMMR/MSI-H Gastric/GEJ Adenocarcinoma Phase II Study

Who this might be right for
Adenocarcinoma - GEJGastric Adenocarcinoma
GERCOR - Multidisciplinary Oncology Cooperative Group 89
Large-scale testing (Phase 3)Study completedNCT02563002
What this trial is testing

Study of Pembrolizumab (MK-3475) vs Standard Therapy in Participants With Microsatellite Instability-High (MSI-H) or Mismatch Repair Deficient (dMMR) Stage IV Colorectal Carcinoma (MK-3475-177/KEYNOTE-177)

Who this might be right for
Colorectal Carcinoma
Merck Sharp & Dohme LLC 307
Testing effectiveness (Phase 2)Study completedNCT01876511
What this trial is testing

Study of MK-3475 in Patients With Microsatellite Unstable (MSI) Tumors (Cohorts A, B and C)

Who this might be right for
MSI Positive Colorectal CancerMSI Negative Colorectal CancerMSI Positive Non-Colorectal Cancers
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 113
Early research (Phase 1)Study completedNCT03053466
What this trial is testing

APL-501 Study for Select Advanced or Relapsed/Recurrent Solid Tumors

Who this might be right for
Solid TumorMicrosatellite InstabilityMismatch Repair Deficiency+1 more
Apollomics (Australia) Pty. Ltd. 30
Large-scale testing (Phase 3)Active Not RecruitingNCT05239741
What this trial is testing

Study of Pembrolizumab (MK-3475) Versus Chemotherapy in Chinese Participants With Stage IV Colorectal Cancer (MK-3475-C66)

Who this might be right for
Colorectal Neoplasms
Merck Sharp & Dohme LLC 100
Large-scale testing (Phase 3)Looking for participantsNCT05770102
What this trial is testing

DETERMINE Trial Treatment Arm 02: Atezolizumab in Adult, Paediatric and Teenage/Young Adult Patients With Cancers With High Tumour Mutational Burden (TMB) or Microsatellite Instability-high (MSI-high) or Proven Constitutional Mismatch Repair Deficiency (CMMRD) Disposition

Who this might be right for
MalignancyMalignant NeoplasmLymphoproliferative Disorders+7 more
Cancer Research UK 30
Testing effectiveness (Phase 2)Looking for participantsNCT07244705
What this trial is testing

ABT-301 Plus Tislelizumab With Bevacizumab in pMMR/Non-MSI-H Locally Advanced or mCRC

Who this might be right for
Colorectal Cancer (Diagnosis)Colorectal Cancer MetastaticColorectal Cancer (CRC)+1 more
Anbogen Therapeutics, Inc. 66
Testing effectiveness (Phase 2)Active Not RecruitingNCT04817826
What this trial is testing

TremelImumab aNd Durvalumab For the Non-operatIve Management (NOM) of MSI-high Resectable GC/GEJC.

Who this might be right for
Gastric CancerMicrosatellite Instability
Gruppo Oncologico del Nord-Ovest 31
Large-scale testing (Phase 3)Active Not RecruitingNCT05078047
What this trial is testing

Study Comparing the Standard Administration of IO Versus the Same IO Administered Each 3 Months in Patients in Response After 6 Months of Standard IO

Who this might be right for
Lung Cancer MetastaticRenal Cell CarcinomaHead and Neck Cancer+12 more
UNICANCER 646
Testing effectiveness (Phase 2)Looking for participantsNCT03736889
What this trial is testing

Tislelizumab (Anti-Programmed Cell Death Protein-1 (PD-1) Antibody) in MSI-H or dMMR Solid Tumors

Who this might be right for
MSI-H/dMMR Solid Tumors
BeiGene 200
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07266025
What this trial is testing

Adebrelimab Combined With Induction Chemotherapy or SHR-8068 for Mismatch Repair-Deficient/Microsatellite Instability-High (dMMR/MSI-H) Locally Advanced Gastric/Gastroesophageal Junction Adenocarcinoma：A Randomized, Non-comparative Phase 2 Study

Who this might be right for
Gastric AdenocarcinomaGastroesophageal AdenocarcinomaMismatch Repair Deficient or MSI-High Solid Tumors+1 more
Shanghai Zhongshan Hospital 30
Not applicableUnknownNCT03561350
What this trial is testing

Detect Microsatellite Instability Status in Blood Sample of Advanced Colorectal Cancer Patients by Next-Generation Sequencing

Who this might be right for
Colorectal Neoplasms
Shanghai Minimally Invasive Surgery Center 60
Not applicableUnknownNCT00232960
What this trial is testing

Postoperative Radiotherapy According to Molecular Analysis of Surgical Margins of Oral and Oropharyngeal SCC

Who this might be right for
Oral CancerOropharynx Cancer
Gustave Roussy, Cancer Campus, Grand Paris 310
Not applicableUnknownNCT06004713
What this trial is testing

Registry Study in MSI/dMMR Solid Tumors

Who this might be right for
DMMR CancerMSI-HSolid Tumor
Peking University Cancer Hospital & Institute 190
Not applicableStudy completedNCT03485196
What this trial is testing

The Relationship Between Microsatellite Instability and Efficacy of Fluorouracil Based Adjuvant Chemotherapy in Gastric Cancer After Operation

Who this might be right for
Gastric Cancer
Affiliated Hospital of Qinghai University 1,000
Not applicableUnknownNCT00220246
What this trial is testing

Clinical and Molecular Characterization of Familial Microsatellite Stable Colorectal Cancer

Who this might be right for
Colorectal Neoplasms
Radboud University Medical Center 130
Testing effectiveness (Phase 2)Study completedNCT05535569
What this trial is testing

Phase Ib/II Study to Evaluate the Safety and Efficacy of Nivolumab in Combination With Paclitaxel in Epstein-Barr Virus(EBV)-Related, or Microsatellite Instability-High (MSI-H), or Programmed Cell Death Ligand 1 (PD-L1) Positive Advanced Gastric Cancer

Who this might be right for
Recurrent/Metastatic Gastric Cancer
Yonsei University 50
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