Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Microsatellite Instability-High”

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 0 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT05199272
What this trial is testing

A Phase 1/2a Study of 23ME-00610 in Patients With Advanced Solid Malignancies

Who this might be right for
Solid TumorClear Cell Renal Cell CarcinomaEpithelial Ovarian Cancer+6 more
23andMe, Inc. 141
Early research (Phase 1)Ended earlyNCT04187872
What this trial is testing

LITT and Pembrolizumab in Recurrent Brain Metastasis

Who this might be right for
MelanomaNon-small Cell Lung Carcinoma (NSCLC)Renal Cell Carcinoma (RCC)+12 more
University of Florida 10
Testing effectiveness (Phase 2)Study completedNCT02060188
What this trial is testing

Nivolumab Alone or Nivolumab Combination Therapy in Colon Cancer That Has Come Back or Has Spread

Who this might be right for
Microsatellite Unstable Colorectal CancerMicrosatellite Stable Colorectal CancerMismatch Repair Proficient Colorectal Cancer+1 more
Bristol-Myers Squibb 385
Testing effectiveness (Phase 2)Study completedNCT03435107
What this trial is testing

Durvalumab for MSI-H or POLE Mutated Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
Asan Medical Center 33
Not applicableUnknownNCT05645094
What this trial is testing

Neoadjuvant Envafolimab in Resectable and Locally Advanced MSI-H/dMMR Rectal Cancer

Who this might be right for
Locally Advanced Rectal CarcinomaMSI-High
Fudan University 38
Early research (Phase 1)Not Yet RecruitingNCT07593144
What this trial is testing

A Single-Arm, Open-Label Phase Ia/Ib Clinical Trial Evaluating the Safety, Tolerability, Pharmacokinetic Profile, and Preliminary Efficacy of FS-207 in Patients With Advanced Solid Tumors With High Microsatellite Instability (MSI-H)

Who this might be right for
Advanced Solid Tumors
Foresight Therapeutics (Hefei) Co., Ltd. 156
Testing effectiveness (Phase 2)UnknownNCT04715633
What this trial is testing

PD-1 Inhibitors Combined With VEGF Inhibitors for Locally Advanced dMMR/MSI-H Colorectal Cancer

Who this might be right for
Colorectal CancerMicrosatellite Instability High
Sun Yat-sen University 53
Large-scale testing (Phase 3)Active Not RecruitingNCT02997228
What this trial is testing

Testing the Addition of Atezolizumab to Combination Chemotherapy or Atezolizumab Alone for Metastatic Colon or Rectal Cancer, the COMMIT Study

Who this might be right for
Metastatic Colorectal AdenocarcinomaStage IV Colorectal Cancer AJCC v7
National Cancer Institute (NCI) 120
Early research (Phase 1)Ended earlyNCT04272034
What this trial is testing

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099318 in Participants With Advanced Solid Tumors

Who this might be right for
Advanced Solid TumorsMSI-H/dMMR TumorsCutaneous Squamous Cell Carcinoma+15 more
Incyte Corporation 105
Early research (Phase 1)Active Not RecruitingNCT05544929
What this trial is testing

Safety and Efficacy of KFA115 Alone and in Combo With Pembrolizumab in Patients With Select Advanced Cancers

Who this might be right for
Carcinoma, Non-Small-Cell LungCutaneous MelanomaCarcinoma, Renal Cell+9 more
Novartis Pharmaceuticals 126
Early research (Phase 1)Looking for participantsNCT04777994
What this trial is testing

Study With ABBV-CLS-484 in Participants With Locally Advanced or Metastatic Tumors

Who this might be right for
Advanced Solid Tumor Cancer
Calico Life Sciences LLC 248
Testing effectiveness (Phase 2)UnknownNCT05429866
What this trial is testing

Immunological Variables Associated to ICI Toxicity in Cancer Patients

Who this might be right for
Breast CancerMelanomaNon Small Cell Lung Cancer+10 more
Jules Bordet Institute 441
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07009145
What this trial is testing

QL1706 Plus Bevacizumab for Unresectable or Metastatic MSI-H/dMMR CRC

Who this might be right for
Unresectable Colorectal CancerMetastatic Colorectal Cancer (CRC)MSI-H/dMMR Colorectal Cancer
Qianfoshan Hospital 22
Not applicableNot Yet RecruitingNCT07645742
What this trial is testing

Pilot Study of Intermittent Fasting With Immune Checkpoint Inhibitors

Who this might be right for
Cancer (Advanced Stage)
West Virginia University 90
Testing effectiveness (Phase 2)UnknownNCT05913570
What this trial is testing

Cadonilimab as Neoadjuvant Therapy in Resectable Stage II-III MSI-H/dMMR Colorectal Cancer

Who this might be right for
Colorectal CancerMismatch Repair-deficient (dMMR)Microsatellite Instability-high (MSI-H)+1 more
LiuYing 22
Testing effectiveness (Phase 2)UnknownNCT04636008
What this trial is testing

Sintilimab Plus Hypofractionated Radiotherapy for MSI-H/dMMR Rectal Cancer

Who this might be right for
Anti-PD-1 AntibodyRadiotherapyRectal Cancer+2 more
West China Hospital 20
Testing effectiveness (Phase 2)Study completedNCT03436563
What this trial is testing

M7824 in Patients With Metastatic Colorectal Cancer or With Advanced Solid Tumors With Microsatellite Instability

Who this might be right for
Colon AdenocarcinomaHigh-Frequency Microsatellite InstabilityMetastatic Malignant Solid Neoplasm+8 more
M.D. Anderson Cancer Center 4
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06118658
What this trial is testing

Chemotherapy Sequential Tislelizumab After Radical Resection in Patients With dMMR/MSI-H or POLE/POLD1 Mutations

Who this might be right for
GastricColorectal Adenocarcinoma
China Medical University, China 30
Testing effectiveness (Phase 2)Looking for participantsNCT03667170
What this trial is testing

KN035 for dMMR/MSI-H Advanced Solid Tumors

Who this might be right for
Solid Tumor
3D Medicines (Sichuan) Co., Ltd. 200
Testing effectiveness (Phase 2)UnknownNCT03544723
What this trial is testing

Safety and Efficacy of p53 Gene Therapy Combined With Immune Checkpoint Inhibitors in Solid Tumors.

Who this might be right for
Solid TumorLymphoma
MultiVir, Inc. 40
Next Page