Testing effectiveness (Phase 2)Ended earlyNCT03791398What this trial is testingBrUOG 379 Phase Ib/II Trial ONC201 + Nivolumab in MSS mCRCWho this might be right forMetastatic Colorectal Cancer Brown University 13
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07007728What this trial is testingIparomlimab/Tuvonralimab Combined With Bevacizumab and CAPEOX as Conversion Therapy for Colorectal Cancer Liver MetastasisWho this might be right forColorectal NeoplasmsSecondary Malignant Neoplasm of Liver Peking University Cancer Hospital & Institute 54
Testing effectiveness (Phase 2)Active Not RecruitingNCT06699836What this trial is testingCLOVER - CCR5-targeting Leronlimab With Oral Chemotherapy and VEGF-inhibitor Enriched RegimenWho this might be right forMetastatic Colorectal Cancer (mCRC) CytoDyn, Inc. 66
Testing effectiveness (Phase 2)Looking for participantsNCT06634875What this trial is testingIsunakinra Alone and in Combination With Pembrolizumab in Patients With Colorectal Cancer (MSS)Who this might be right forColorectal Cancer Metastatic Buzzard Pharmaceuticals 20
Testing effectiveness (Phase 2)Study completedNCT02060188What this trial is testingNivolumab Alone or Nivolumab Combination Therapy in Colon Cancer That Has Come Back or Has SpreadWho this might be right forMicrosatellite Unstable Colorectal CancerMicrosatellite Stable Colorectal CancerMismatch Repair Proficient Colorectal Cancer+1 more Bristol-Myers Squibb 385
Testing effectiveness (Phase 2)WithdrawnNCT04145193What this trial is testingNovel Oncology Therapies in Combination With Adjuvant Chemo in High-risk MSS-CRCWho this might be right forMicrosatellite-stable Colorectal Cancer MedImmune LLC
Early research (Phase 1)Ended earlyNCT04609579What this trial is testingStudy of SNX281 in Subjects With Advanced Solid Tumors and LymphomaWho this might be right forAdvanced Solid TumorAdvanced Lymphoma Stingthera, Inc. 27
Early research (Phase 1)Study completedNCT04362839What this trial is testingRegorafenib, Ipilimumab and Nivolumab for the Treatment of Chemotherapy Resistant Microsatellite Stable Metastatic Colorectal CancerWho this might be right forAdvanced Colon AdenocarcinomaMetastatic Colon AdenocarcinomaMetastatic Colorectal Adenocarcinoma+22 more City of Hope Medical Center 39
Very early researchNot Yet RecruitingNCT07486492What this trial is testingUsing Healthy Gut Bacteria to Boost Immune Treatment for Advanced Bowel CancerWho this might be right forColorectal Cancer MetastaticFecal Microbiota Transplantation The First Affiliated Hospital of Xiamen University 10
Early research (Phase 1)Ended earlyNCT04044430What this trial is testingEncorafenib, Binimetinib, and Nivolumab in Treating Microsatellite Stable BRAF V600E Metastatic Colorectal CancerWho this might be right forMetastatic Colon AdenocarcinomaMetastatic Colorectal AdenocarcinomaMetastatic Microsatellite Stable Colorectal Carcinoma+25 more University of California, San Francisco 2
Testing effectiveness (Phase 2)Study completedNCT03631407What this trial is testingSafety and Efficacy of Vicriviroc (MK-7690) in Combination With Pembrolizumab (MK-3475) in Participants With Advanced/Metastatic Microsatellite Stable (MSS) Colorectal Cancer (CRC) (MK-7690-046)Who this might be right forColorectal Neoplasms Merck Sharp & Dohme LLC 41
Post-approval studies (Phase 4)UnknownNCT02887365What this trial is testingA Phase II Study of Tegafur-Uracil as Maintenance Chemotherapy in Patients With Stage II of Colon CancerWho this might be right forMSI-L/MSSStage II Colon Cancer National Taiwan University Hospital 300
Testing effectiveness (Phase 2)Looking for participantsNCT07079631What this trial is testingA Clinical Study to Test if an Investigational Treatment Called BNT314 When Used in Combination With Another Investigational Treatment Pumitamig (BNT327) and Chemotherapy, is Beneficial and Safe for Patients With Advanced Colorectal CancerWho this might be right forMetastatic Colorectal Cancer BioNTech SE 482
Not applicableStudy completedNCT04482608What this trial is testingThe mCRC Patients With pMMR/MSS or dMMR/MSI-H Status Received Palliative Chemotherapy Efficacy and SurvivalWho this might be right forColorectal Cancer MetastaticMismatch Repair DeficiencyMicrosatellite Instability High Sun Yat-sen University 671
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07662031What this trial is testingTovecimig Plus FOLFIRI in Second Line Metastatic Colorectal CancerWho this might be right forColorectal CancerMetastatic Colorectal Cancer Washington University School of Medicine 25
Testing effectiveness (Phase 2)Active Not RecruitingNCT06268015What this trial is testingBotensilimab and Balstilimab Optimization in Colorectal CancerWho this might be right forColorectal Cancer Nicholas DeVito, MD 16
Testing effectiveness (Phase 2)Ended earlyNCT05572684What this trial is testingA Safety, Tolerability and Efficacy Study of NC410 Plus Pembrolizumab in Participants With Advanced Unresectable or Metastatic Solid TumorsWho this might be right forAdvanced or Metastatic Solid TumorsMicrosatellite Instability LowMicrosatellite Instability High+9 more NextCure, Inc. 97
Testing effectiveness (Phase 2)Looking for participantsNCT07147231What this trial is testingTesting the Effectiveness of the Anti-cancer Drug Pidnarulex (CX-5461), in Combination With Another Anti-cancer Drug Cemiplimab (REGN2810), in Treating Refractory Microsatellite Stable Colorectal CancerWho this might be right forMetastatic Colorectal AdenocarcinomaRefractory Colorectal AdenocarcinomaStage III Colorectal Cancer AJCC v8+2 more National Cancer Institute (NCI) 86
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06872606What this trial is testingShort-Course Radiotherapy Combined with Intracavitary Brachytherapy Followed by Pucotenlimab, Bevacizumab, Oxaliplatin, and Trifluridine/Tipiracil (TAS-102) for Total Neoadjuvant Therapy of Microsatellite Stable (MSS) Locally Advanced Low Rectal CancerWho this might be right forRectal Adenocarcinoma Sir Run Run Shaw Hospital 33
Testing effectiveness (Phase 2)UnknownNCT03993626What this trial is testingA Trial of CXD101 in Combination With Nivolumab in Patients With Metastatic Microsatellite-Stable Colorectal CancerWho this might be right forColorectal Neoplasms Malignant Celleron Therapeutics Ltd. 55