Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Mid-low Locally Advanced Rectal Cancer”

29 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 29 results

Not applicableNot Yet RecruitingNCT07249021
What this trial is testing

This is a Multicentre International Study Evaluating CT-based IGABT With / Without Either TRUS During BT/Pre BT MR as Per IBS-GECESTRO-ABS Recommendations for Target contouring-as an Alternative to MRIGABT for Cervical Cancer From Implementation Perspectives Under EMBRACE-III:TRIPLET IMPACT Study.

Who this might be right for
Locally Advanced Cervical CancerBrachytherapyCT+1 more
Homi Bhabha Cancer Hospital & Research Centre 1,200
Testing effectiveness (Phase 2)Study completedNCT06333769
What this trial is testing

Modified SCRT Followed by Tislelizumab Plus CAPOX for Locally Advanced Rectal Cancer

Who this might be right for
Mid-low Rectal Cancer
Fujian Cancer Hospital 38
Testing effectiveness (Phase 2)Looking for participantsNCT05245474
What this trial is testing

Neoadjuvant Long-course Chemoradiation Plus PD-1 Blockade for Mid-low Locally Advanced Rectal Cancer

Who this might be right for
Locally Advanced Rectal Cancer
Beijing Friendship Hospital 186
Testing effectiveness (Phase 2)Looking for participantsNCT06204094
What this trial is testing

Node-sparing Radiotherapy Combined With Total Neoadjuvant CAPOX and Sintilimab for MSS Middle and Low Rectal Cancer

Who this might be right for
Locally Advanced Rectal Cancer
Jinhua Central Hospital 37
Large-scale testing (Phase 3)Active Not RecruitingNCT06507371
What this trial is testing

Node-sparing Short-Course Radiation Combined With CAPOX and Tislelizumab for MSS Rectal Cancer

Who this might be right for
Rectal Cancer
Sir Run Run Shaw Hospital 170
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07248020
What this trial is testing

A Phase II Single-Arm Study of High-Bioavailability Curcumin as Neoadjuvant Chemoradiotherapy in Mid-to-Low Rectal Cancer: Integrated Clinical and Translational Analysis of Tumor Tissue

Who this might be right for
Rectal CancerLocally Advanced Rectal CancerRadiation-Induced Enteritis+2 more
Chang Gung Memorial Hospital 72
Post-approval studies (Phase 4)Enrolling By InvitationNCT06931808
What this trial is testing

Intestinal Microbiota Transplantation, Radiochemotherapy and Sintilimab in Localized Advanced Colon Cancer

Who this might be right for
Localized Advanced Rectal Adenocarcinoma
First Affiliated Hospital of Ningbo University 20
Testing effectiveness (Phase 2)UnknownNCT06304987
What this trial is testing

Neoadjuvant Chemoradiotherapy Combined With PD-1 Inhibitor and PCSK9 Inhibitor for pMMR/MSS Locally Advanced Mid-low Rectal Cancer

Who this might be right for
Locally Advanced Rectal Cancer
Beijing Friendship Hospital 50
Not applicableStudy completedNCT06024356
What this trial is testing

Neoadjuvant Chemoradiotherapy Combined With PD-1 Inhibitor and Thymalfasin for Locally Advanced Mid-low Rectal Cancer

Who this might be right for
Colorectal Neoplasms
Beijing Friendship Hospital 47
Large-scale testing (Phase 3)Looking for participantsNCT07505472
What this trial is testing

Efficacy and Safety Comparison of Short-course Radiotherapy Followed by CapeOX Chemotherapy Plus Toripalimab With or Without Concurrent Surufatinib in Neoadjuvant Therapy for Mid-to-low Localized Rectal Cancer of High-risk Criteria

Who this might be right for
Rectal Cancer
The First Hospital of Jilin University 212
Early research (Phase 1)UnknownNCT04906044
What this trial is testing

Total Neoadjuvant Treatment Plus PD-1 in Mid-Low Locally Advanced Rectal Cancer

Who this might be right for
TislelizumabLocally Advanced Rectal CancerTotal Neoadjuvant Treatment+1 more
The First Hospital of Jilin University 46
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07662278
What this trial is testing

RSIFN-co in Combination With Total Neo-adjuvant Therapy in Subjects With Mid-low Locally Advanced Rectal Cancer

Who this might be right for
Mid-low Locally Advanced Rectal Cancer
Sichuan Huiyang Life Science and Technology Corporation 90
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06014944
What this trial is testing

Short-course Radiotherapy Combined With Furoquintinib and PD-1 Monoclonal Antibody

Who this might be right for
Rectal Cancer
Changhai Hospital 30
Not applicableUnknownNCT03042000
What this trial is testing

Multicenter, Prospective, RCT：Investigation of Combined Modality Therapy for Locally Advanced Mid/Low Rectal Cancer.

Who this might be right for
Rectal Cancer, AdenocarcinomaNeoadjuvant Chemoradiation
Peking Union Medical College Hospital 1,200
Not applicableNot Yet RecruitingNCT06879899
What this trial is testing

MRD-Guided Surveillance in Locally Advanced Mid-Low Rectal Cancer (SURVEILLANCE-III)

Who this might be right for
Colorectal Cancer (CRC)
Fudan University 139
Testing effectiveness (Phase 2)Looking for participantsNCT05972655
What this trial is testing

Nodes-sparing Short-course Radiation Combined With CAPOX and Tislelizumab for MSS Middle and Low Rectal Cancer

Who this might be right for
Low Rectal Cancer
Sir Run Run Shaw Hospital 32
Testing effectiveness (Phase 2)Looking for participantsNCT06923345
What this trial is testing

Modified Long-Course Radiotherapy Followed by Chemotherapy and PD-1 Inhibitor for MSS/pMMR High-risk Mid/Low LARC (MODIFI-RC-I)

Who this might be right for
Rectal CancerNeoadjuvant TherapiesImmune Checkpoint Therapy+1 more
Sixth Affiliated Hospital, Sun Yat-sen University 80
Not applicableUnknownNCT04672603
What this trial is testing

Complete Versus Partial Preservation of Denonvilliers' Fascia on Urogenital Function in Locally Advanced Rectal Cancer

Who this might be right for
Rectal CancerAdvanced Cancer
Sixth Affiliated Hospital, Sun Yat-sen University 214
Testing effectiveness (Phase 2)Looking for participantsNCT07347951
What this trial is testing

A Single-center, Phase II Study on Efficacy & Safety of SCRT+CAPOX+Serplulimab+Bevacizumab for MSS Rectal Cancer

Who this might be right for
Locally Advanced Rectal Cancer (LARC)
First Affiliated Hospital of Wenzhou Medical University 30
Testing effectiveness (Phase 2)UnknownNCT02022852
What this trial is testing

Neoadjuvant Sequential Therapy in Locally Advanced Mid/Low Rectal Cancer

Who this might be right for
Rectal Cancer
Harbin Medical University 80
Next Page