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Results for “Mismatch Repair- Deficient Rectal Cancer”

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Showing 20 of 0 results

Large-scale testing (Phase 3)Looking for participantsNCT05236972
What this trial is testing

PACE: PD-1 Antibody For dMMR/MSI-H Stage III Colorectal Cancer

Who this might be right for
Colorectal Carcinoma
Sun Yat-sen University 323
Large-scale testing (Phase 3)Not Yet RecruitingNCT07740720
What this trial is testing

The Duration of Dostarlimab in Untreated Mismatch Repair Deficient (dMMR)/ Microsatellite Instability-high (MSI-H) Locally Advanced Rectal Cancer

Who this might be right for
Neoplasms, Rectal
GlaxoSmithKline 90
Testing effectiveness (Phase 2)UnknownNCT04636008
What this trial is testing

Sintilimab Plus Hypofractionated Radiotherapy for MSI-H/dMMR Rectal Cancer

Who this might be right for
Anti-PD-1 AntibodyRadiotherapyRectal Cancer+2 more
West China Hospital 20
Not applicableLooking for participantsNCT07269249
What this trial is testing

Real-world Efficacy and Safety of Neoadjuvant Dostarlimab in Patients With dMMR/MSI-H Locally Advanced Rectal Cancer

Who this might be right for
Locally Advanced Rectal Cancer (LARC)
National Cancer Institute, Naples 50
Large-scale testing (Phase 3)Active Not RecruitingNCT05652894
What this trial is testing

HX008 Compared to Chemotherapy in the First-Line Treatment of Subjects With MSI-H/dMMR Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
Taizhou Hanzhong biomedical co. LTD 190
Large-scale testing (Phase 3)Study completedNCT02563002
What this trial is testing

Study of Pembrolizumab (MK-3475) vs Standard Therapy in Participants With Microsatellite Instability-High (MSI-H) or Mismatch Repair Deficient (dMMR) Stage IV Colorectal Carcinoma (MK-3475-177/KEYNOTE-177)

Who this might be right for
Colorectal Carcinoma
Merck Sharp & Dohme LLC 307
Testing effectiveness (Phase 2)Looking for participantsNCT05272709
What this trial is testing

TT-702 in Patients With Advanced Solid Tumours.

Who this might be right for
Advanced Solid Tumors
Cancer Research UK 60
Not applicableNot Yet RecruitingNCT07780305
What this trial is testing

ABCSG R07 Rectal Cancer Registry

Who this might be right for
Rectal CancerAdenocarcinoma of Rectum
Austrian Breast & Colorectal Cancer Study Group 600
Testing effectiveness (Phase 2)Active Not RecruitingNCT02983578
What this trial is testing

Danvatirsen and Durvalumab in Treating Patients With Advanced and Refractory Pancreatic, Non-Small Cell Lung Cancer, and Mismatch Repair Deficient Colorectal Cancer

Who this might be right for
Advanced Colorectal CarcinomaAdvanced Lung Non-Small Cell CarcinomaLung Non-Small Cell Carcinoma+22 more
M.D. Anderson Cancer Center 39
Testing effectiveness (Phase 2)Active Not RecruitingNCT04895722
What this trial is testing

Evaluation of Co-formulated Pembrolizumab/Quavonlimab (MK-1308A) Versus Other Treatments in Participants With Microsatellite Instability-High (MSI-H) or Mismatch Repair Deficient (dMMR) Stage IV Colorectal Cancer (CRC) (MK-1308A-008/KEYSTEP-008).

Who this might be right for
Colorectal Cancer
Merck Sharp & Dohme LLC 302
Early research (Phase 1)Ended earlyNCT06625515
What this trial is testing

First-in-Human Study of ATX-559, an Oral Inhibitor of DHX9, in Patients With Advanced or Metastatic Solid Tumors, and Molecularly Defined Cancers

Who this might be right for
Advanced Solid TumorsBreast Cancer RecurrentColorectal Cancer Metastatic+3 more
Accent Therapeutics 17
Testing effectiveness (Phase 2)Looking for participantsNCT06903858
What this trial is testing

Toripalimab Plus Celecoxib for dMMR/MSI-H Locally Advanced Colorectal Cancer

Who this might be right for
Colorectal CancerMicrosatellite Instability HighMismatch Repair Deficiency
Sun Yat-sen University 105
Testing effectiveness (Phase 2)Active Not RecruitingNCT06710847
What this trial is testing

Investigate the Safety, Pharmacokinetics, and Preliminary Effectiveness of GSK4418959 Alone or in Combination With Other Anti-cancer Agents in Participants With Solid Tumors

Who this might be right for
Neoplasms, ColorectalSolid TumorColon Cancer+2 more
GlaxoSmithKline 14
Testing effectiveness (Phase 2)Looking for participantsNCT03926338
What this trial is testing

Neoadjuvant Toripalimab With or Without Celecoxib in dMMR/MSI-H Colorectal Cancer

Who this might be right for
Colorectal CancerMismatch Repair-deficient (dMMR)Microsatellite Instability-high (MSI-H)+1 more
Sun Yat-sen University 270
Testing effectiveness (Phase 2)Looking for participantsNCT06362369
What this trial is testing

Oral 7HP349 (Alintegimod) in Combination With Ipilimumab Followed by Nivolumab Monotherapy

Who this might be right for
Advanced CancerAdvanced Solid TumorMelanoma+15 more
7 Hills Pharma, LLC 126
Not applicableLooking for participantsNCT06613165
What this trial is testing

Exploring the Treatment Duration of PD-1 Neoadjuvant Therapy in Stage II-III dMMR Rectal Cancer

Who this might be right for
Immune-related Adverse EventNeoadjuvant TherapydMMR Colorectal Cancer
Xijing Hospital 100
Not applicableLooking for participantsNCT07450612
What this trial is testing

Liquid Biopsy and Machine Learning for Early Colorectal Cancer, Adenomas, Lynch Cancers, and Residual Disease Detection

Who this might be right for
Colorectal CancerAdenoma ColonAdenoma Colon Polyp+16 more
San Raffaele University 1,200
Early research (Phase 1)Looking for participantsNCT06004245
What this trial is testing

Evaluate the Safety, Pharmacokinetics, and Anti-Tumor Activity of VVD-133214 as Monotherapy and in Combination in Participants With Advanced Solid Tumors

Who this might be right for
Advanced Solid TumorsColorectal Cancer
Vividion Therapeutics, Inc. 280
Large-scale testing (Phase 3)Active Not RecruitingNCT05239741
What this trial is testing

Study of Pembrolizumab (MK-3475) Versus Chemotherapy in Chinese Participants With Stage IV Colorectal Cancer (MK-3475-C66)

Who this might be right for
Colorectal Neoplasms
Merck Sharp & Dohme LLC 100
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07807800
What this trial is testing

DES-1357 in People With Deficient Mismatch Repair (dMMR)/Microsatellite Instability-High (MSI-H) Metastatic Colorectal Cancer (mCRC)

Who this might be right for
Metastatic Colorectal Cancer (CRC)
D. E. Shaw Research, LLC 88
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