Testing effectiveness (Phase 2)Ended earlyNCT05609656What this trial is testingElectroporation and Immunotherapy in Metastatic Colorectal CancerWho this might be right forMetastatic Colorectal Cancer Ismail Gögenur 4
Testing effectiveness (Phase 2)WithdrawnNCT05582031What this trial is testingRegorafenib With Tislelizumab in Patients With Selected Mismatch Repair-Proficient/Microsatellite Stable CancersWho this might be right forAnal Squamous Cell CarcinomaColorectal NeoplasmsSoft Tissue Sarcoma+5 more Translational Research in Oncology
Large-scale testing (Phase 3)Not Yet RecruitingNCT06832917What this trial is testingShort-course Radiation (SCRT) Followed by 6 Cycles of Cadonilimab Plus MFOLFOX6 As Neoadjuvant Therapy for Patients with Locally Advanced Rectal Cancer (LARC): a Multicenter, Two-arm Parallel, Open-label, Randomised Phase III Trial (NeoCaCRT-III)Who this might be right forRectal Cancer Wan He 238
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07175636What this trial is testingQL1706 With Short-Course Radiotherapy and Chemotherapy for MSS Rectal CancerWho this might be right forLocally Advanced Rectal Cancer (LARC)Mismatch Repair-Proficient (pMMR) Rectal CancerNon-metastatic Rectal Cancer Sun Yat-sen University 66
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07359456What this trial is testingTesting Ivonescimab in Combination With Chemotherapy in Patients With Metastatic Colorectal Cancers Without Liver MetastasesWho this might be right forMetastatic Colorectal Cancer UNICANCER 130
Early research (Phase 1)Ended earlyNCT04108481What this trial is testingImmunotherapy With Y90-RadioEmbolization for Metastatic Colorectal CancerWho this might be right forColorectal Cancer MetastaticColon CancerMetastatic Colorectal Cancer+7 more University of Iowa 5
Testing effectiveness (Phase 2)UnknownNCT05980689What this trial is testingCombination of AK104 and Neoadjuvant Chemoradiotherapy in pMMR/MSS Locally Advanced Rectal CancerWho this might be right forLocally Advanced Rectal Cancer Sun Yat-sen University 33
Testing effectiveness (Phase 2)UnknownNCT05160727What this trial is testingRadiotherapy Combined With Tislelizumab and Irinotecan in MSS/pMMR Recurrence and Metastatic Colorectal CancerWho this might be right forMismatch Repair-proficientColorectal Cancer MetastaticMicrosatellite Stable Zhejiang Cancer Hospital 44
Testing effectiveness (Phase 2)Looking for participantsNCT06864013What this trial is testingSCRT Combined With Chemotherapy and Iparomlimab and Tuvonralimab in MSS or pMMR Patients With Locally Advanced Rectal CancerWho this might be right forLocally Advanced Rectal Cancer (LARC) First Affiliated Hospital of Zhejiang University 116
Testing effectiveness (Phase 2)Looking for participantsNCT06856837What this trial is testing- IKF/AIO-QUINTIS - Evaluating Fruquintinib in Combination With Tislelizumab in Microsatellite Stable / Proficient Mismatch Repair (MSS/pMMR) Metastatic Colorectal Cancer Without Active Liver MetastasesWho this might be right forMetastatic Colorectal Cancer Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest 140
Testing effectiveness (Phase 2)Study completedNCT04126733What this trial is testingStudy on the Effectiveness and Safety of the Combination of the Two Drugs Regorafenib and Nivolumab in Patients With Colorectal Cancer (Cancer of the Colon or Rectum Classified as Proficient Mismatch Repair and Microsatellite Stable)Who this might be right forColorectal Cancer Bayer 70
Testing effectiveness (Phase 2)Looking for participantsNCT06522919What this trial is testingSequential Immunochemotherapy Treatment with Pembrolizumab Plus Dendritic Cell (DC) Vaccine Followed by Trifluridine/Tipiracil Plus Bevacizumab in Refractory Mismatch-repair-proficient (pMMR) or Microsatellite-stable (MSS) Metastatic Colorectal CancerWho this might be right forColorectal Cancer MetastaticMicrosatellite Stable Colorectal CarcinomaRefractory Mismatch-repair-proficient (pMMR) Metastatic Colorectal Cancer Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS
Testing effectiveness (Phase 2)Looking for participantsNCT07079631What this trial is testingA Clinical Study to Test if an Investigational Treatment Called BNT314 When Used in Combination With Another Investigational Treatment BNT327 and Chemotherapy, is Beneficial and Safe for Patients With Advanced Colorectal CancerWho this might be right forMetastatic Colorectal Cancer BioNTech SE 482
Testing effectiveness (Phase 2)Looking for participantsNCT07244705What this trial is testingABT-301 Plus Tislelizumab With Bevacizumab in pMMR/Non-MSI-H Locally Advanced or mCRCWho this might be right forColorectal Cancer (Diagnosis)Colorectal Cancer MetastaticColorectal Cancer (CRC)+1 more Anbogen Therapeutics, Inc. 66
Testing effectiveness (Phase 2)Ended earlyNCT05733611What this trial is testingRP2/RP3 in Combination With Atezolizumab and Bevacizumab for the Treatment of Patients With CRCWho this might be right forRefractory Metastatic Colorectal CancerpMMRMSS Replimune, Inc. 5
Testing effectiveness (Phase 2)Active Not RecruitingNCT05205330What this trial is testingVorbipiprant (CR6086) / Balstilimab (AGEN2034) Combination in Stage IV Refractory pMMR - MSS CRC, and Other Metastatic GI CancersWho this might be right forRefractory Metastatic Colorectal CancerSolid TumorMetastatic Microsatellite-stable Colorectal Cancer+3 more Rottapharm Biotech 107
Testing effectiveness (Phase 2)Looking for participantsNCT06850103What this trial is testingSCRT-CAPEOX-Serplulimab for MSS/pMMR Rectal Cancer With OligometastasesWho this might be right forColorectal CarcinomaOligometastasespMMR+2 more First Affiliated Hospital of Zhejiang University 51