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Results for “Mitochondrial Encephalomyopathy”

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Showing 20 of 0 results

Testing effectiveness (Phase 2)WithdrawnNCT03866954
What this trial is testing

Trial of Erythrocyte Encapsulated Thymidine Phosphorylase In Mitochondrial Neurogastrointestinal Encephalomyopathy

Who this might be right for
Mitochondrial DiseasesMetabolic DiseaseInborn Errors of Metabolism
St George's, University of London
Testing effectiveness (Phase 2)Ended earlyNCT02473445
What this trial is testing

A Long-term Extension of Study RP103-MITO-001 (NCT02023866) to Assess Cysteamine Bitartrate Delayed-release Capsules (RP103) in Children With Inherited Mitochondrial Disease

Who this might be right for
Mitochondrial Diseases
Amgen 22
Testing effectiveness (Phase 2)Looking for participantsNCT04802707
What this trial is testing

Deoxynucleosides Pyrimidines as Treatment for Mitochondrial Depletion Syndrome

Who this might be right for
Mitochondrial DiseasesMitochondrial EncephalomyopathyMitochondrial Encephalopathy+2 more
Kenneth Myers, MD 200
Testing effectiveness (Phase 2)Study completedNCT05972954
What this trial is testing

OMT-28 in Patients With Primary Mitochondrial Disease (PMD) (PMD-OPTION)

Who this might be right for
Primary Mitochondrial Disease
Omeicos Therapeutics GmbH 28
Very early researchStudy completedNCT01339494
What this trial is testing

Nitric Oxide Production in MELAS Syndrome

Who this might be right for
MELAS Syndrome
Baylor College of Medicine 30
Early research (Phase 1)Study completedNCT02544217
What this trial is testing

A Dose-escalating Clinical Trial With KH176

Who this might be right for
MELASLHONLeigh Syndrome+2 more
Khondrion BV 32
Early research (Phase 1)Study completedNCT03952234
What this trial is testing

L-Citrulline Dose Finding Safety Study in MELAS

Who this might be right for
MELAS Syndrome
Baylor College of Medicine 10
Testing effectiveness (Phase 2)Temporarily pausedNCT04846036
What this trial is testing

The KHENERGYC Study

Who this might be right for
Mitochondrial DiseasesMitochondrial DNA tRNALeu(UUR) m.3243A<G MutationMELAS+1 more
Khondrion BV 24
Not applicableLooking for participantsNCT05848271
What this trial is testing

Natural History Study of Patients with HPDL Mutations

Who this might be right for
Mitochondrial EncephalomyopathiesHereditary Spastic ParaplegiaSpastic Paraplegia+4 more
University of California, San Diego 50
Large-scale testing (Phase 3)Ended earlyNCT04378075
What this trial is testing

Evaluate Efficacy and Safety of Vatiquinone for Treating Mitochondrial Disease in Participants With Refractory Epilepsy

Who this might be right for
Mitochondrial DiseasesDrug Resistant EpilepsyLeigh Disease+5 more
PTC Therapeutics 68
Not applicableLooking for participantsNCT01694940
What this trial is testing

North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)

Who this might be right for
Mitochondrial DisordersMitochondrial Genetic DisordersMitochondrial Diseases+2 more
Columbia University 1,000
Not applicableLooking for participantsNCT06213090
What this trial is testing

Patterns of Neurodevelopmental Disorders

Who this might be right for
Neurodevelopmental DisordersAutism Spectrum DisorderPediatric Autoimmune Neuropsychiatric Disorder Associated With Streptococcal Infection+5 more
Richard Frye 1,000
Testing effectiveness (Phase 2)Study completedNCT06644534
What this trial is testing

Assess TTI-0102 vs Placebo in MELAS Patients

Who this might be right for
MELAS SyndromeMitochondrial Encephalomyopathy, Lactic Acidosis and Stroke-like Episodes (MELAS)
Thiogenesis Therapeutics, Inc. 9
Testing effectiveness (Phase 2)Active Not RecruitingNCT06961344
What this trial is testing

An Open-label Extension Safety Study of MELAS Patients Who Completed TIS6463-203 (PRIZM)

Who this might be right for
Mitochondrial Encephalopathy, Lactic Acidosis and Stroke-Like Episodes (MELAS Syndrome)
Tisento Therapeutics 44
Not applicableLooking for participantsNCT03137355
What this trial is testing

The International Registry for Leigh Syndrome

Who this might be right for
Leigh SyndromeLeigh DiseaseLeigh's Necrotizing Encephalopathy+2 more
The University of Texas Health Science Center, Houston 200
Not applicableNot Yet RecruitingNCT06013397
What this trial is testing

Effectiveness of Ketogenic Diet in MELAS Syndrome

Who this might be right for
MELAS SyndromeKetogenic Dieting
Second Affiliated Hospital, Zhejiang University, School of Medicine 100
Not applicableLooking for participantsNCT01532791
What this trial is testing

Natural History Study - Mitochondrial Disease

Who this might be right for
MELAS or m.3243 A>G Mitochondrial DNA Mutation Carrier
Columbia University 300
Very early researchStudy completedNCT01252979
What this trial is testing

Ketones & Mitochondrial Heteroplasmy

Who this might be right for
MELAS SyndromeMitochondrial Diseases
The University of Texas Health Science Center, Houston 13
Early research (Phase 1)WithdrawnNCT02427178
What this trial is testing

MNGIE Allogeneic Hematopoietic Stem Cell Transplant Safety Study

Who this might be right for
Mitochondrial Neurogastrointestinal Encephalomyopathy (MNGIE)
Michio Hirano, MD
Not applicableStudy completedNCT04948138
What this trial is testing

Glutamine Supplement in MELAS (Mitochondrial Encephalopathy, Lactic Acidosis, and Stroke-like Episodes) Syndrome

Who this might be right for
MELAS Syndrome
Jesús González de la Aleja Tejera 9
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