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Results for “Mitochondrial Genetic Disorders”

346 trials

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Showing 20 of 346 results

Not applicableStudy completedNCT03432871
What this trial is testing

Nicotinamide Riboside and Mitochondrial Biogenesis

Who this might be right for
Mitochondrial DiseasesMitochondrial MyopathiesProgressive External Ophthalmoplegia+4 more
Cambridge University Hospitals NHS Foundation Trust 13
Not applicableActive Not RecruitingNCT07217158
What this trial is testing

Role of ROS and cAMP-PKA Biomarkers in ADPKD

Who this might be right for
Autosomal Dominant Polycystic Kidney Disease
Mayo Clinic 100
Not applicableStudy completedNCT06539598
What this trial is testing

Respiratory Training in Friedreich's Ataxia

Who this might be right for
Friedreich Ataxia
University of Florida 1
Not applicableStudy completedNCT01625663
What this trial is testing

Heart and Muscle Metabolism in Barth Syndrome

Who this might be right for
Barth Syndrome
Duke University 64
Not applicableAvailableNCT06931834
What this trial is testing

Expanded Access Program for R007 (Probucol) Tablets in Adults With Mitochondrial Disease and Chronic Kidney Disease

Who this might be right for
Mitochondrial DiseaseChronic Kidney Disease
RiboNova Inc.
Not applicableUnknownNCT06224114
What this trial is testing

Coloured-light in Retinitis Pigmentosa.

Who this might be right for
Retinitis Pigmentosa
University College, London 70
Not applicableLooking for participantsNCT06813443
What this trial is testing

Characterization of Patients With Cardiomyopathy to Identify Critical Patients Candidates for Cardiac Transplantation

Who this might be right for
CardiomyopathiesAmyloidosis CardiacFabry Disease+14 more
IRCCS Azienda Ospedaliero-Universitaria di Bologna 700
Early research (Phase 1)Study completedNCT00000768
What this trial is testing

Comparative Pharmacokinetic Study of Oral Ganciclovir After Treatment With Intravenous Ganciclovir for Cytomegalovirus Gastrointestinal Disease in AIDS Patients

Who this might be right for
ColitisHIV Infections
National Institute of Allergy and Infectious Diseases (NIAID) 24
Not applicableLooking for participantsNCT02435940
What this trial is testing

Inherited Retinal Degenerative Disease Registry

Who this might be right for
Eye Diseases HereditaryRetinal DiseaseAchromatopsia+25 more
Foundation Fighting Blindness 20,000
Testing effectiveness (Phase 2)Active Not RecruitingNCT06402123
What this trial is testing

A Phase 2b Study of Zagociguat in Patients With MELAS

Who this might be right for
Mitochondrial Encephalopathy, Lactic Acidosis and Stroke-Like Episodes (MELAS Syndrome)
Tisento Therapeutics 43
Large-scale testing (Phase 3)Study completedNCT02652767
What this trial is testing

Efficacy Study of GS010 for the Treatment of Vision Loss up to 6 Months From Onset in LHON Due to the ND4 Mutation

Who this might be right for
Optic, Atrophy, Hereditary, Leber
GenSight Biologics 39
Not applicableStudy completedNCT00002299
What this trial is testing

The Safety and Effectiveness of Ganciclovir Plus Interferon Beta in Preventing the Return of Cytomegalovirus (CMV) of the Eyes in Patients With AIDS

Who this might be right for
Cytomegalovirus RetinitisHIV Infections
Hoffmann-La Roche
Not applicableUnknownNCT00002301
What this trial is testing

Foscarnet in the Treatment of Cytomegalovirus (CMV) of the Eyes in Patients With AIDS Who Have Not Had Success With Ganciclovir

Who this might be right for
Cytomegalovirus RetinitisHIV Infections
Astra USA
Large-scale testing (Phase 3)Study completedNCT00697073
What this trial is testing

Study to Assess the Safety and Tolerability of Idebenone in the Treatment of Friedreich's Ataxia Patients

Who this might be right for
Friedreich's Ataxia
Santhera Pharmaceuticals 68
Large-scale testing (Phase 3)Study completedNCT02593773
What this trial is testing

Safety, Tolerability and Efficacy of ACTIMMUNE® Dose Escalation in Friedreich's Ataxia Study

Who this might be right for
Friedreich's Ataxia
Amgen 86
Not applicableStudy completedNCT00002095
What this trial is testing

A Randomized, Double-Blind Study of the Efficacy and Safety of Oral Ganciclovir for the Prevention of CMV Disease in People Infected With the Human Immunodeficiency Virus

Who this might be right for
Cytomegalovirus InfectionsHIV Infections
Hoffmann-La Roche 700
Early research (Phase 1)Study completedNCT00078481
What this trial is testing

Phase 1 Trial of Idebenone to Treat Patients With Friedreich's Ataxia

Who this might be right for
Friedreich Ataxia
National Institute of Neurological Disorders and Stroke (NINDS) 16
Not applicableStudy completedNCT00004353
What this trial is testing

Study of the Metabolism of Pyruvate and Related Problems in Patients With Lactic Acidemia

Who this might be right for
Mitochondrial MyopathyMELAS SyndromeLactic Acidosis
National Center for Research Resources (NCRR) 35
Not applicableStudy completedNCT03295071
What this trial is testing

REALITY LHON Registry

Who this might be right for
Leber Hereditary Optic Neuropathy
GenSight Biologics 44
Not applicableLooking for participantsNCT03056794
What this trial is testing

Natural History and Advanced Genetic Study of Pyruvate Dehydrogenase Complex Deficiencies

Who this might be right for
Pyruvate Dehydrogenase Complex Deficiency Disease
University of Pittsburgh 150
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