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Results for “Mixed Phenotype Acute Leukemia (MPAL)”

67 trials

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Showing 20 of 67 results

Large-scale testing (Phase 3)Active Not RecruitingNCT05602194
What this trial is testing

Studying the Effect of Levocarnitine in Protecting the Liver From Chemotherapy for Leukemia or Lymphoma

Who this might be right for
B Acute Lymphoblastic LeukemiaB Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1B Acute Lymphoblastic Leukemia, BCR-ABL1-Like+3 more
Children's Oncology Group 440
Large-scale testing (Phase 3)Active Not RecruitingNCT03007147
What this trial is testing

Imatinib Mesylate and Combination Chemotherapy in Treating Patients With Newly Diagnosed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia

Who this might be right for
Acute Lymphoblastic LeukemiaB Acute Lymphoblastic LeukemiaMixed Phenotype Acute Leukemia+1 more
Children's Oncology Group 475
Early research (Phase 1)Active Not RecruitingNCT06034470
What this trial is testing

Combination Chemotherapy (FLAG-Ida) With Pivekimab Sunirine (PVEK) for the Treatment of Newly Diagnosed Adverse Risk Acute Myeloid Leukemia and Other High-Grade Myeloid Neoplasms

Who this might be right for
Acute Myeloid LeukemiaMixed Phenotype Acute LeukemiaMyelodysplastic Syndrome+2 more
Fred Hutchinson Cancer Center 30
Early research (Phase 1)Ended earlyNCT03198234
What this trial is testing

Use of T-allo10 in Hematopoietic Stem Cell Transplantation (HSCT) for Blood Disorders

Who this might be right for
AML - Acute Myeloid LeukemiaMDS (Myelodysplastic Syndrome)Mixed Phenotype Acute Leukemia+3 more
Roncarolo, Maria Grazia, MD 5
Early research (Phase 1)Active Not RecruitingNCT06325748
What this trial is testing

SENTI-202: Off-the-shelf Logic Gated CAR NK Cell Therapy in Adults With CD33 and/or FLT3 Blood Cancers Including AML/MDS

Who this might be right for
AML/MDSCD33 Expressing Hematological MalignanciesFLT3 Expressing Hematological Malignancies
Senti Biosciences 21
Large-scale testing (Phase 3)Active Not RecruitingNCT05316701
What this trial is testing

Precision-T: A Randomized Study of Orca-T in Recipients Undergoing Allogeneic Transplantation for Hematologic Malignancies

Who this might be right for
Acute Myeloid LeukemiaAcute Lymphoid LeukemiaMixed Phenotype Acute Leukemia+4 more
Orca Biosystems, Inc. 187
Early research (Phase 1)Study completedNCT05326516
What this trial is testing

Revumenib in Combination With Chemotherapy in Participants With R/R Acute Leukemia

Who this might be right for
Relapsed/Refractory LeukemiasAcute Lymphoblastic LeukemiaAcute Lymphocytic Leukemia+3 more
Syndax Pharmaceuticals 30
Testing effectiveness (Phase 2)Active Not RecruitingNCT05761171
What this trial is testing

Revumenib in Combination With Chemotherapy for Patients Diagnosed With Relapsed or Refractory Leukemia

Who this might be right for
Recurrent Acute Leukemia of Ambiguous LineageRecurrent Acute Lymphoblastic LeukemiaRecurrent Acute Myeloid Leukemia Due to Lineage Switch From Acute Leukemia of Ambiguous Lineage+9 more
Children's Oncology Group 78
Early research (Phase 1)Looking for participantsNCT03802695
What this trial is testing

Orca-Q in Recipients Undergoing Allogeneic Transplantation for Hematologic Malignancies

Who this might be right for
Acute Myeloid LeukemiaMyelodysplastic SyndromesMixed Phenotype Acute Leukemia+1 more
Orca Biosystems, Inc. 300
Testing effectiveness (Phase 2)Study completedNCT05433532
What this trial is testing

Study of Azacitidine，Venetoclax，and Flumatinib in Newly Diagnosed Ph-positive Acute Leukemia and CML-AP/BP Patients

Who this might be right for
Philadelphia ChromosomeAcute Myeloid LeukemiaAcute Lymphoblastic Leukemia+2 more
The First Affiliated Hospital of Soochow University 20
Testing effectiveness (Phase 2)Looking for participantsNCT07256210
What this trial is testing

Feasibility and Safety of Donor-derived NK-cell Infusions for Leukemia Relapse Prophylaxis After Hematopoietic Stem Cell Transplantation

Who this might be right for
Acute Myeloid LeukemiaAcute Lymphoblastic T-cell LeukemiaMixed Phenotype Acute Leukemia
Federal Research Institute of Pediatric Hematology, Oncology and Immunology 15
Testing effectiveness (Phase 2)Looking for participantsNCT03128034
What this trial is testing

211^At-BC8-B10 Before Donor Stem Cell Transplant in Treating Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Myelodysplastic Syndrome, or Mixed-Phenotype Acute Leukemia

Who this might be right for
Acute Lymphoblastic LeukemiaAcute Myeloid Leukemia Arising From Previous Myelodysplastic SyndromeAcute Myeloid Leukemia+9 more
Fred Hutchinson Cancer Center 75
Early research (Phase 1)WithdrawnNCT02578511
What this trial is testing

Standard Maintenance POMP/D Plus Ixazomib Maintenance Therapy in Adult Patients With Acute Lymphoblastic Leukemia, Lymphoblastic Lymphoma or Mixed Phenotype Acute Leukemia in Complete Remission (CR)

Who this might be right for
Acute Lymphoblastic Leukemia in Complete RemissionLymphoblastic Lymphoma in Complete RemissionMixed Phenotype Acute Leukemia in Complete Remission
Ehab L Atallah
Testing effectiveness (Phase 2)Study completedNCT02828358
What this trial is testing

Azacitidine and Combination Chemotherapy in Treating Infants With Acute Lymphoblastic Leukemia and KMT2A Gene Rearrangement

Who this might be right for
Acute Leukemia of Ambiguous LineageB Acute Lymphoblastic LeukemiaMixed Phenotype Acute Leukemia
National Cancer Institute (NCI) 78
Testing effectiveness (Phase 2)UnknownNCT04964518
What this trial is testing

APG-2575 in Combination With Azacitidine in Patients With Acute Myeloid Leukemia (AML)

Who this might be right for
AML, Adult
Ascentage Pharma Group Inc. 24
Testing effectiveness (Phase 2)Looking for participantsNCT04195633
What this trial is testing

Donor Stem Cell Transplant With Treosulfan, Fludarabine, and Total-Body Irradiation for the Treatment of Hematological Malignancies

Who this might be right for
Acute LeukemiaAcute Lymphoblastic LeukemiaAcute Myeloid Leukemia+16 more
Fred Hutchinson Cancer Center 60
Testing effectiveness (Phase 2)Enrolling By InvitationNCT07517510
What this trial is testing

HVA in the Treatment of Mixed-Phenotype Acute Leukemia(MPAL).

Who this might be right for
Newly Diagnosed Mixed Phenotype Acute Leukemia (MPAL)
Guangdong Second Provincial General Hospital 40
Testing effectiveness (Phase 2)Looking for participantsNCT03779854
What this trial is testing

Naive T Cell Depletion for Preventing Chronic Graft-versus-Host Disease in Children and Young Adults With Blood Cancers Undergoing Donor Stem Cell Transplant

Who this might be right for
Acute Biphenotypic LeukemiaAcute LeukemiaAcute Leukemia of Ambiguous Lineage+14 more
Fred Hutchinson Cancer Center 68
Not applicableNot Yet RecruitingNCT07008027
What this trial is testing

Real World Asparaginase Therapy Toxicity

Who this might be right for
Drug Toxicity
St. Jude Children's Research Hospital 200
Not applicableNot Yet RecruitingNCT06991920
What this trial is testing

Immune-targeted Combination With Chemotherapy for Acute Leukemia of Ambiguous Lineage

Who this might be right for
Adult ALLMPAL
Institute of Hematology & Blood Diseases Hospital, China 50
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