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Results for “Mixed Phenotype Acute Leukemia (MPAL)”

68 trials

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Showing 20 of 68 results

Large-scale testing (Phase 3)Active Not RecruitingNCT05316701
What this trial is testing

Precision-T: A Randomized Study of Orca-T in Recipients Undergoing Allogeneic Transplantation for Hematologic Malignancies

Who this might be right for
Acute Myeloid LeukemiaAcute Lymphoid LeukemiaMixed Phenotype Acute Leukemia+4 more
Orca Biosystems, Inc. 187
Early research (Phase 1)Study completedNCT05326516
What this trial is testing

Revumenib in Combination With Chemotherapy in Participants With R/R Acute Leukemia

Who this might be right for
Relapsed/Refractory LeukemiasAcute Lymphoblastic LeukemiaAcute Lymphocytic Leukemia+3 more
Syndax Pharmaceuticals 30
Early research (Phase 1)Looking for participantsNCT04872478
What this trial is testing

Pharmacokinetic and Safety Study of MRX-2843 in Adolescents and Adults With Relapsed/Refractory AML, ALL, or MPAL

Who this might be right for
Acute Myeloid LeukemiaAcute Lymphoblastic LeukemiaMixed Phenotype Acute Leukemia
Meryx, Inc. 50
Testing effectiveness (Phase 2)Active Not RecruitingNCT04904588
What this trial is testing

HLA-Mismatched Unrelated Donor Hematopoietic Cell Transplantation With Post-Transplantation Cyclophosphamide

Who this might be right for
Acute Lymphoblastic LeukemiaAcute Myelogenous LeukemiaMixed Phenotype Acute Leukemia+5 more
Center for International Blood and Marrow Transplant Research 300
Early research (Phase 1)Active Not RecruitingNCT02879695
What this trial is testing

Blinatumomab and Nivolumab With or Without Ipilimumab in Treating Patients With Poor-Risk Relapsed or Refractory CD19+ Precursor B-Lymphoblastic Leukemia

Who this might be right for
Recurrent B Acute Lymphoblastic LeukemiaRecurrent Mixed Phenotype Acute LeukemiaRefractory B Acute Lymphoblastic Leukemia+1 more
National Cancer Institute (NCI) 28
Large-scale testing (Phase 3)Looking for participantsNCT05327894
What this trial is testing

Interfant-21 Treatment Protocol for Infants Under 1 Year With KMT2A-rearranged ALL or Mixed Phenotype Acute Leukemia

Who this might be right for
Acute Lymphoblastic LeukemiaMixed Phenotype Acute Leukemia
Princess Maxima Center for Pediatric Oncology 160
Testing effectiveness (Phase 2)Study completedNCT05433532
What this trial is testing

Study of Azacitidine，Venetoclax，and Flumatinib in Newly Diagnosed Ph-positive Acute Leukemia and CML-AP/BP Patients

Who this might be right for
Philadelphia ChromosomeAcute Myeloid LeukemiaAcute Lymphoblastic Leukemia+2 more
The First Affiliated Hospital of Soochow University 20
Testing effectiveness (Phase 2)Looking for participantsNCT07356154
What this trial is testing

Revumenib and Mezigdomide in People With Leukemia

Who this might be right for
LeukemiaAcute LeukemiaRelapse Leukemia+5 more
Memorial Sloan Kettering Cancer Center 52
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07573670
What this trial is testing

Bcl-2 Inhibitor Combined With Azacitidine for Newly Diagnosed Mixed Phenotype Acute Leukemia

Who this might be right for
Newly Diagnosed Mixed Phenotype Acute Leukemia
The First Affiliated Hospital of Soochow University 52
Early research (Phase 1)Looking for participantsNCT05476770
What this trial is testing

Tagraxofusp in Pediatric Patients With Relapsed or Refractory CD123 Expressing Hematologic Malignancies

Who this might be right for
Hematologic MalignancyAMLALL+8 more
Therapeutic Advances in Childhood Leukemia Consortium 54
Testing effectiveness (Phase 2)Looking for participantsNCT03128034
What this trial is testing

211^At-BC8-B10 Before Donor Stem Cell Transplant in Treating Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Myelodysplastic Syndrome, or Mixed-Phenotype Acute Leukemia

Who this might be right for
Acute Lymphoblastic LeukemiaAcute Myeloid Leukemia Arising From Previous Myelodysplastic SyndromeAcute Myeloid Leukemia+9 more
Fred Hutchinson Cancer Center 75
Large-scale testing (Phase 3)Active Not RecruitingNCT05457556
What this trial is testing

Mismatched Related Donor Versus Matched Unrelated Donor Stem Cell Transplantation for Children, Adolescents, and Young Adults With Acute Leukemia or Myelodysplastic Syndrome

Who this might be right for
Acute Lymphoblastic LeukemiaAcute Myeloid LeukemiaMixed Phenotype Acute Leukemia+1 more
Children's Oncology Group 66
Not applicableNot Yet RecruitingNCT06991920
What this trial is testing

Immune-targeted Combination With Chemotherapy for Acute Leukemia of Ambiguous Lineage

Who this might be right for
Adult ALLMPAL
Institute of Hematology & Blood Diseases Hospital, China 50
Early research (Phase 1)Looking for participantsNCT03802695
What this trial is testing

Orca-Q in Recipients Undergoing Allogeneic Transplantation for Hematologic Malignancies

Who this might be right for
Acute Myeloid LeukemiaMyelodysplastic SyndromesMixed Phenotype Acute Leukemia+1 more
Orca Biosystems, Inc. 300
Large-scale testing (Phase 3)Active Not RecruitingNCT05602194
What this trial is testing

Studying the Effect of Levocarnitine in Protecting the Liver From Chemotherapy for Leukemia or Lymphoma

Who this might be right for
B Acute Lymphoblastic LeukemiaB Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1B Acute Lymphoblastic Leukemia, BCR-ABL1-Like+3 more
Children's Oncology Group 440
Testing effectiveness (Phase 2)Active Not RecruitingNCT03779854
What this trial is testing

Naive T Cell Depletion for Preventing Chronic Graft-versus-Host Disease in Children and Young Adults With Blood Cancers Undergoing Donor Stem Cell Transplant

Who this might be right for
Acute Biphenotypic LeukemiaAcute LeukemiaAcute Leukemia of Ambiguous Lineage+14 more
Fred Hutchinson Cancer Center 45
Early research (Phase 1)Active Not RecruitingNCT06034470
What this trial is testing

Combination Chemotherapy (FLAG-Ida) With Pivekimab Sunirine (PVEK) for the Treatment of Newly Diagnosed Adverse Risk Acute Myeloid Leukemia and Other High-Grade Myeloid Neoplasms

Who this might be right for
Acute Myeloid LeukemiaMixed Phenotype Acute LeukemiaMyelodysplastic Syndrome+2 more
Fred Hutchinson Cancer Center 30
Testing effectiveness (Phase 2)Study completedNCT02828358
What this trial is testing

Azacitidine and Combination Chemotherapy in Treating Infants With Acute Lymphoblastic Leukemia and KMT2A Gene Rearrangement

Who this might be right for
Acute Leukemia of Ambiguous LineageB Acute Lymphoblastic LeukemiaMixed Phenotype Acute Leukemia
National Cancer Institute (NCI) 78
Early research (Phase 1)Active Not RecruitingNCT03843528
What this trial is testing

Vorinostat Dose-escalation After Allogeneic Hematopoietic Cell Transplantation

Who this might be right for
Acute Myeloid LeukemiaMyelodysplastic SyndromesMixed Phenotype Acute Leukemia+1 more
Johns Hopkins All Children's Hospital 15
Testing effectiveness (Phase 2)Enrolling By InvitationNCT07517510
What this trial is testing

HVA in the Treatment of Mixed-Phenotype Acute Leukemia(MPAL).

Who this might be right for
Newly Diagnosed Mixed Phenotype Acute Leukemia (MPAL)
Guangdong Second Provincial General Hospital 40
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