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Results for “Mixed-Lineage Acute Leukemias”

70 trials

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Showing 20 of 70 results

Testing effectiveness (Phase 2)UnknownNCT05066958
What this trial is testing

Ex-vivo Primed Memory Donor Lymphocyte Infusion to Boost Anti-viral Immunity After T-cell Depleted HSCT

Who this might be right for
Acute Myeloid LeukemiaHigh Risk Acute Myeloid LeukemiaAcute Lymphoblastic Leukemia, in Relapse+4 more
Federal Research Institute of Pediatric Hematology, Oncology and Immunology 20
Testing effectiveness (Phase 2)Study completedNCT02799147
What this trial is testing

GVHD Prophylaxis With Post-transplantation Bendamustine in Refractory Leukemia

Who this might be right for
Leukemia, Acute LymphoblasticAcute Myeloid LeukemiaMixed-Lineage Acute Leukemias
St. Petersburg State Pavlov Medical University 27
Early research (Phase 1)Looking for participantsNCT03826992
What this trial is testing

Venetoclax Combined With Vyxeos (CPX-351) for Participants With Relapsed or Refractory Acute Leukemia

Who this might be right for
Leukemia
Children's Hospital Medical Center, Cincinnati 21
Early research (Phase 1)Study completedNCT02529813
What this trial is testing

CD19-Specific T-cells in Treating Patients With Advanced Lymphoid Malignancies

Who this might be right for
Acute Biphenotypic LeukemiaAcute Lymphoblastic LeukemiaBlasts 5 Percent or More of Bone Marrow Nucleated Cells+6 more
M.D. Anderson Cancer Center 26
Not applicableStudy completedNCT01804101
What this trial is testing

Liposomal Cytarabine-Daunorubicin CPX-351 in Treating Patients With Untreated Myelodysplastic Syndrome or Acute Myeloid Leukemia

Who this might be right for
Acute Biphenotypic LeukemiaAcute Myeloid LeukemiaMyelodysplastic Syndrome+1 more
Fred Hutchinson Cancer Center 48
Early research (Phase 1)Looking for participantsNCT05735184
What this trial is testing

Investigate the Safety and Tolerability of Ziftomenib in Combination With Venetoclax/Azacitidine, Venetoclax, 7+3, or 7+3+Quizartinib in Patients With AML

Who this might be right for
Acute Myeloid LeukemiaMixed Lineage Leukemia Gene MutationRefractory AML+7 more
Kura Oncology, Inc. 420
Early research (Phase 1)WithdrawnNCT03807063
What this trial is testing

Rivogenlecleucel Donor Lymphocyte Immunotherapy in Treating Patients With Recurrent Blood Cancers After Stem Cell Transplant

Who this might be right for
Acute Bilineal LeukemiaMyelodysplastic/Myeloproliferative NeoplasmMyelodysplastic/Myeloproliferative Neoplasm, Unclassifiable+9 more
Fred Hutchinson Cancer Center
Testing effectiveness (Phase 2)Study completedNCT01690520
What this trial is testing

Donor Umbilical Cord Blood Transplant With or Without Ex-vivo Expanded Cord Blood Progenitor Cells in Treating Patients With Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Chronic Myelogenous Leukemia, or Myelodysplastic Syndromes

Who this might be right for
Acute Biphenotypic LeukemiaAcute Lymphoblastic Leukemia in RemissionAcute Myeloid Leukemia in Remission+2 more
Nohla Therapeutics, Inc. 163
Early research (Phase 1)WithdrawnNCT05170828
What this trial is testing

Cryopreserved MMUD BM With PTCy for Hematologic Malignancies

Who this might be right for
Acute LeukemiaMyelodysplastic SyndromesT-lymphoblastic Lymphoma+4 more
Ossium Health, Inc.
Testing effectiveness (Phase 2)Ended earlyNCT03404193
What this trial is testing

Venetoclax and Decitabine in Treating Participants With Relapsed/Refractory Acute Myeloid Leukemia or Relapsed High-Risk Myelodysplastic Syndrome

Who this might be right for
Acute Myeloid LeukemiaAcute Myeloid Leukemia Arising From Previous Myelodysplastic SyndromeBlastic Plasmacytoid Dendritic Cell Neoplasm+12 more
M.D. Anderson Cancer Center 235
Testing effectiveness (Phase 2)Looking for participantsNCT02115295
What this trial is testing

Cladribine, Idarubicin, Cytarabine, and Venetoclax in Treating Patients With Acute Myeloid Leukemia, High-Risk Myelodysplastic Syndrome, or Blastic Phase Chronic Myeloid Leukemia

Who this might be right for
Acute Biphenotypic LeukemiaAcute Myeloid LeukemiaBlast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive+11 more
M.D. Anderson Cancer Center 508
Testing effectiveness (Phase 2)Ended earlyNCT04874194
What this trial is testing

Omacetaxine and Venetoclax for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome Harboring Mutant RUNX1

Who this might be right for
Hematopoietic and Lymphoid Cell NeoplasmRecurrent Acute Biphenotypic LeukemiaRecurrent Acute Myeloid Leukemia+4 more
M.D. Anderson Cancer Center 24
Testing effectiveness (Phase 2)Study completedNCT01858740
What this trial is testing

Selective Depletion of CD45RA+ T Cells From Allogeneic Peripheral Blood Stem Cell Grafts in Preventing GVHD in Children

Who this might be right for
Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 PositiveAcute Biphenotypic LeukemiaAcute Leukemia of Ambiguous Lineage+15 more
Fred Hutchinson Cancer Center 20
Early research (Phase 1)Study completedNCT01684150
What this trial is testing

A Phase 1, Open-Label, Dose-Escalation & Expanded Cohort, Continuous IV Infusion, Multi-center Study of the Safety, Tolerability,PK & PD of EPZ-5676 in Treatment Relapsed/Refractory Patients With Leukemias Involving

Who this might be right for
Acute Myeloid LeukemiaAcute Lymphoblastic LeukemiaMyelodysplastic Syndrome+1 more
Epizyme, Inc. 51
Testing effectiveness (Phase 2)Looking for participantsNCT06477549
What this trial is testing

BeFluBu vs FluBuRux Conditioning in Haploidentical HCT

Who this might be right for
Acute Lymphoblastic LeukemiaAcute Myeloid LeukemiaBiphenotypic Acute Leukemia+3 more
St. Petersburg State Pavlov Medical University 220
Testing effectiveness (Phase 2)Active Not RecruitingNCT04128501
What this trial is testing

Venetoclax and Azacitidine for the Treatment of Acute Myeloid Leukemia in the Post-Transplant Setting

Who this might be right for
Acute Bilineal LeukemiaAcute Biphenotypic LeukemiaAcute Myeloid Leukemia+3 more
M.D. Anderson Cancer Center 100
Testing effectiveness (Phase 2)Looking for participantsNCT04047641
What this trial is testing

Cladribine, Idarubicin, Cytarabine, and Quizartinib in Treating Patients With Newly Diagnosed, Relapsed, or Refractory Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

Who this might be right for
Acute Myeloid LeukemiaBlasts 20 Percent or More of Bone Marrow Nucleated CellsHigh Risk Myelodysplastic Syndrome+5 more
M.D. Anderson Cancer Center 80
Early research (Phase 1)Ended earlyNCT04526795
What this trial is testing

Fludarabine, Cytarabine, and Pegcrisantaspase for the Treament of Relapsed or Refractory Leukemia

Who this might be right for
Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 PositiveRecurrent Acute Biphenotypic LeukemiaRecurrent Acute Lymphoblastic Leukemia+8 more
M.D. Anderson Cancer Center 19
Testing effectiveness (Phase 2)Ended earlyNCT03195010
What this trial is testing

Management of Platelet Transfusion Therapy in Patients With Blood Cancer or Treatment-Induced Thrombocytopenia

Who this might be right for
Acute Biphenotypic LeukemiaAcute Lymphoblastic LeukemiaAcute Myeloid Leukemia+11 more
Fred Hutchinson Cancer Center 4
Testing effectiveness (Phase 2)Looking for participantsNCT05805605
What this trial is testing

Allo HSCT Using RIC and PTCy for Hematological Diseases

Who this might be right for
Acute Myelogenous LeukemiaAcute Lymphocytic LeukemiaBiphenotypic Acute Leukemia+15 more
Masonic Cancer Center, University of Minnesota 56
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