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Results for “Mixed-Lineage Acute Leukemias”

72 trials

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Showing 20 of 72 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT04975919
What this trial is testing

Venetoclax in Combination With Decitabine and Cedazuridine for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia

Who this might be right for
Recurrent Acute Biphenotypic LeukemiaRecurrent Acute Myeloid LeukemiaRefractory Acute Biphenotypic Leukemia+1 more
M.D. Anderson Cancer Center 20
Testing effectiveness (Phase 2)Study completedNCT03267186
What this trial is testing

Ibrutinib in Preventing Acute Leukemia in Patients After Reduced-Intensity Conditioning and Stem Cell Transplant

Who this might be right for
Acute Biphenotypic LeukemiaAcute Lymphoblastic LeukemiaAcute Myeloid Leukemia+2 more
Andrew Rezvani 8
Testing effectiveness (Phase 2)Looking for participantsNCT06508099
What this trial is testing

Vitamin A and D Supplementation in Allogeneic HCT

Who this might be right for
Acute Lymphoblastic LeukemiaAcute Myeloid LeukemiaBiphenotypic Acute Leukemia+5 more
St. Petersburg State Pavlov Medical University 220
Testing effectiveness (Phase 2)Looking for participantsNCT04988555
What this trial is testing

Enzomenib (DSP-5336) in Patients With Acute Leukemia (Horizen-1)

Who this might be right for
Leukemia, Myeloid, AcuteLeukemia, Lymphocytic, AcuteMultiple Myeloma+1 more
Sumitomo Pharma America, Inc. 606
Early research (Phase 1)Looking for participantsNCT05735184
What this trial is testing

Investigate the Safety and Tolerability of Ziftomenib in Combination With Venetoclax/Azacitidine, Venetoclax, 7+3, or 7+3+Quizartinib in Patients With AML

Who this might be right for
Acute Myeloid LeukemiaMixed Lineage Leukemia Gene MutationRefractory AML+7 more
Kura Oncology, Inc. 420
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07819396
What this trial is testing

Depletion of CD45RA Positive Naive T Cells for the Prevention of Graft Versus Host Disease in Older Patients Undergoing Allogeneic Hematopoietic Cell Transplantation for Acute Leukemia or Myelodysplastic Syndrome

Who this might be right for
Acute Biphenotypic LeukemiaAcute LeukemiaAcute Leukemia of Ambiguous Lineage+11 more
Fred Hutchinson Cancer Center 52
Early research (Phase 1)Ended earlyNCT04526795
What this trial is testing

Fludarabine, Cytarabine, and Pegcrisantaspase for the Treament of Relapsed or Refractory Leukemia

Who this might be right for
Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 PositiveRecurrent Acute Biphenotypic LeukemiaRecurrent Acute Lymphoblastic Leukemia+8 more
M.D. Anderson Cancer Center 19
Testing effectiveness (Phase 2)Looking for participantsNCT04047641
What this trial is testing

Cladribine, Idarubicin, Cytarabine, and Quizartinib in Treating Patients With Newly Diagnosed, Relapsed, or Refractory Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

Who this might be right for
Acute Myeloid LeukemiaBlasts 20 Percent or More of Bone Marrow Nucleated CellsHigh Risk Myelodysplastic Syndrome+5 more
M.D. Anderson Cancer Center 80
Early research (Phase 1)Study completedNCT01925131
What this trial is testing

S1312, Inotuzumab Ozogamicin and Combination Chemotherapy in Treating Patients With Relapsed or Refractory Acute Leukemia

Who this might be right for
Acute Leukemias of Ambiguous LineageB-cell Adult Acute Lymphoblastic LeukemiaPhiladelphia Chromosome Positive Adult Precursor Acute Lymphoblastic Leukemia+2 more
SWOG Cancer Research Network 50
Early research (Phase 1)Active Not RecruitingNCT02091245
What this trial is testing

Phase I Trial of the Selective Inhibitor of Nuclear Export, KPT-330, in Relapsed Childhood ALL and AML

Who this might be right for
Relapsed Acute Lymphoblastic Leukemia (ALL)Refractory Acute Lymphoblastic Leukemia (ALL)Relapsed Acute Myelogenous Leukemia (AML)+6 more
Dana-Farber Cancer Institute 16
Early research (Phase 1)Looking for participantsNCT03826992
What this trial is testing

Venetoclax Combined With Vyxeos (CPX-351) for Participants With Relapsed or Refractory Acute Leukemia

Who this might be right for
Leukemia
Children's Hospital Medical Center, Cincinnati 21
Testing effectiveness (Phase 2)Study completedNCT03096782
What this trial is testing

Umbilical Cord Blood Transplant With Added Sugar and Chemotherapy and Radiation Therapy in Treating Patients With Leukemia or Lymphoma

Who this might be right for
Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 PositiveAcute Biphenotypic LeukemiaAcute Leukemia+19 more
M.D. Anderson Cancer Center 6
Large-scale testing (Phase 3)Active Not RecruitingNCT06475820
What this trial is testing

Preventing of GVHD With Post-transplantation Cyclophosphamide, Abatacept, Vedolizumab and Baricitinib at Children and Young Adults With Hemoblastosis

Who this might be right for
Acute Lymphoblastic LeukemiaAcute Myeloid LeukemiaBiphenotypic Acute Leukemia+2 more
Federal Research Institute of Pediatric Hematology, Oncology and Immunology 150
Testing effectiveness (Phase 2)Study completedNCT04942730
What this trial is testing

Benadamustine, Fludarabine and Busulfan Conditioning in Recipients of Haploidentical Stem Cell Transplantation (FluBuBe)

Who this might be right for
Leukemia, Acute LymphoblasticMyeloid Leukemia, AcuteBiphenotypic Acute Leukemia+3 more
St. Petersburg State Pavlov Medical University 50
Testing effectiveness (Phase 2)Looking for participantsNCT02115295
What this trial is testing

Cladribine, Idarubicin, Cytarabine, and Venetoclax in Treating Patients With Acute Myeloid Leukemia, High-Risk Myelodysplastic Syndrome, or Blastic Phase Chronic Myeloid Leukemia

Who this might be right for
Acute Biphenotypic LeukemiaAcute Myeloid LeukemiaBlast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive+11 more
M.D. Anderson Cancer Center 508
Testing effectiveness (Phase 2)WithdrawnNCT02718755
What this trial is testing

Phase II Study of Fludarabine, Cytarabine (ARA-C) and Erwinase IV in Patients With Relapsed or Refractory Hematologic Malignancies

Who this might be right for
Hematologic Malignancy
M.D. Anderson Cancer Center
Testing effectiveness (Phase 2)Looking for participantsNCT06477549
What this trial is testing

BeFluBu vs FluBuRux Conditioning in Haploidentical HCT

Who this might be right for
Acute Lymphoblastic LeukemiaAcute Myeloid LeukemiaBiphenotypic Acute Leukemia+3 more
St. Petersburg State Pavlov Medical University 220
Testing effectiveness (Phase 2)Ended earlyNCT01028716
What this trial is testing

Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies

Who this might be right for
Acute Biphenotypic LeukemiaAcute Erythroid Leukemia in RemissionAcute Leukemia in Remission+27 more
Fred Hutchinson Cancer Center 46
Testing effectiveness (Phase 2)Ended earlyNCT03195010
What this trial is testing

Management of Platelet Transfusion Therapy in Patients With Blood Cancer or Treatment-Induced Thrombocytopenia

Who this might be right for
Acute Biphenotypic LeukemiaAcute Lymphoblastic LeukemiaAcute Myeloid Leukemia+11 more
Fred Hutchinson Cancer Center 4
Testing effectiveness (Phase 2)Study completedNCT02220985
What this trial is testing

Selective Depletion of CD45RA+ T Cells From Allogeneic Peripheral Blood Stem Cell Grafts From HLA-Matched Related and Unrelated Donors in Preventing GVHD

Who this might be right for
Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 PositiveAcute Biphenotypic LeukemiaAcute Leukemia of Ambiguous Lineage+20 more
Fred Hutchinson Cancer Center 84
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