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Results for “Mixed-Lineage Acute Leukemias”

70 trials

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Showing 20 of 70 results

Large-scale testing (Phase 3)UnknownNCT03596892
What this trial is testing

Decitabine+BUCY vs BUCY Conditioning Regimen for MLL+ Acute Leukemia Undergoing Allo-HSCT

Who this might be right for
Allogeneic Hematopoietic Stem Cell TransplantationConditionsMixed-lineage-leukemia (MLL)-Rearranged Acute Leukemia
Nanfang Hospital, Southern Medical University 122
Testing effectiveness (Phase 2)Study completedNCT02044796
What this trial is testing

Filgrastim, Cladribine, Cytarabine, and Mitoxantrone Hydrochloride in Treating Patients With Newly Diagnosed or Relapsed/Refractory Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndromes

Who this might be right for
Acute Biphenotypic Leukemiade Novo Myelodysplastic SyndromePreviously Treated Myelodysplastic Syndrome+3 more
Fred Hutchinson Cancer Center 199
Early research (Phase 1)Study completedNCT01684150
What this trial is testing

A Phase 1, Open-Label, Dose-Escalation & Expanded Cohort, Continuous IV Infusion, Multi-center Study of the Safety, Tolerability,PK & PD of EPZ-5676 in Treatment Relapsed/Refractory Patients With Leukemias Involving

Who this might be right for
Acute Myeloid LeukemiaAcute Lymphoblastic LeukemiaMyelodysplastic Syndrome+1 more
Epizyme, Inc. 51
Testing effectiveness (Phase 2)Looking for participantsNCT05805605
What this trial is testing

Allo HSCT Using RIC and PTCy for Hematological Diseases

Who this might be right for
Acute Myelogenous LeukemiaAcute Lymphocytic LeukemiaBiphenotypic Acute Leukemia+15 more
Masonic Cancer Center, University of Minnesota 56
Testing effectiveness (Phase 2)Looking for participantsNCT06013423
What this trial is testing

Cord Blood Transplant, Cyclophosphamide, Fludarabine, and Total-Body Irradiation in Treating Patients With High-Risk Hematologic Diseases

Who this might be right for
Acute Leukemia of Ambiguous LineageAcute Lymphoblastic LeukemiaAcute Myeloid Leukemia+7 more
Fred Hutchinson Cancer Center 54
Testing effectiveness (Phase 2)Study completedNCT01858740
What this trial is testing

Selective Depletion of CD45RA+ T Cells From Allogeneic Peripheral Blood Stem Cell Grafts in Preventing GVHD in Children

Who this might be right for
Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 PositiveAcute Biphenotypic LeukemiaAcute Leukemia of Ambiguous Lineage+15 more
Fred Hutchinson Cancer Center 20
Testing effectiveness (Phase 2)Ended earlyNCT01028716
What this trial is testing

Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies

Who this might be right for
Acute Biphenotypic LeukemiaAcute Erythroid Leukemia in RemissionAcute Leukemia in Remission+27 more
Fred Hutchinson Cancer Center 46
Early research (Phase 1)UnknownNCT00004858
What this trial is testing

Monoclonal Antibody Therapy in Treating Patients With Recurrent Acute Lymphoblastic Leukemia or Non-Hodgkin's Lymphoma

Who this might be right for
LeukemiaLymphoma
Parker Hughes Cancer Center
Early research (Phase 1)WithdrawnNCT05170828
What this trial is testing

Cryopreserved MMUD BM With PTCy for Hematologic Malignancies

Who this might be right for
Acute LeukemiaMyelodysplastic SyndromesT-lymphoblastic Lymphoma+4 more
Ossium Health, Inc.
Testing effectiveness (Phase 2)Active Not RecruitingNCT03404193
What this trial is testing

Venetoclax and Decitabine in Treating Participants With Relapsed/Refractory Acute Myeloid Leukemia or Relapsed High-Risk Myelodysplastic Syndrome

Who this might be right for
Acute Myeloid LeukemiaAcute Myeloid Leukemia Arising From Previous Myelodysplastic SyndromeBlastic Plasmacytoid Dendritic Cell Neoplasm+12 more
M.D. Anderson Cancer Center 235
Testing effectiveness (Phase 2)Looking for participantsNCT04065399
What this trial is testing

Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 Mutation

Who this might be right for
Acute Myeloid LeukemiaAcute Lymphoblastic LeukemiaMixed Lineage Acute Leukemia+2 more
Syndax Pharmaceuticals 447
Testing effectiveness (Phase 2)Ended earlyNCT02399917
What this trial is testing

Lirilumab and Azacitidine in Treating Patients With Refractory or Relapsed Acute Myeloid Leukemia

Who this might be right for
Acute Biphenotypic LeukemiaAcute Myeloid Leukemia Arising From Previous Myelodysplastic SyndromeRecurrent Acute Myeloid Leukemia+1 more
M.D. Anderson Cancer Center 36
Testing effectiveness (Phase 2)Looking for participantsNCT04988555
What this trial is testing

DSP-5336 in Relapsed/Refractory AML/ ALL With or Without MLL Rearrangement or NPM1 Mutation

Who this might be right for
Leukemia, Myeloid, AcuteLeukemia, Lymphocytic, Acute
Sumitomo Pharma America, Inc. 362
Testing effectiveness (Phase 2)Study completedNCT02799147
What this trial is testing

GVHD Prophylaxis With Post-transplantation Bendamustine in Refractory Leukemia

Who this might be right for
Leukemia, Acute LymphoblasticAcute Myeloid LeukemiaMixed-Lineage Acute Leukemias
St. Petersburg State Pavlov Medical University 27
Testing effectiveness (Phase 2)Looking for participantsNCT02727803
What this trial is testing

Personalized NK Cell Therapy in CBT

Who this might be right for
Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 PositiveAcute Biphenotypic LeukemiaAcute Lymphoblastic Leukemia+23 more
M.D. Anderson Cancer Center 100
Very early researchStudy completedNCT00013533
What this trial is testing

Pilot Study of Non-Myeloablative, HLA-Matched Allogeneic Stem Cell Transplantation for Pediatric Hematopoietic Malignancies

Who this might be right for
Hodgkin LymphomaLymphocytic LeukemiaMixed Cell Leukemia+6 more
National Cancer Institute (NCI) 30
Large-scale testing (Phase 3)Active Not RecruitingNCT05515029
What this trial is testing

Preventing of GVHD With Post-transplantation Cyclophosphamide, Abatacept, Vedolizumab and Calcineurin Inhibitor at Patients With Hemoblastosis

Who this might be right for
Acute Lymphoblastic LeukemiaMyeloblastic LeukemiaBiphenotypic Acute Leukemia+3 more
Federal Research Institute of Pediatric Hematology, Oncology and Immunology 56
Testing effectiveness (Phase 2)Study completedNCT02135874
What this trial is testing

Clofarabine, Idarubicin, Cytarabine, Vincristine Sulfate, and Dexamethasone in Treating Patients With Newly Diagnosed or Relapsed Mixed Phenotype Acute Leukemia

Who this might be right for
Acute Bilineal LeukemiaAcute Biphenotypic LeukemiaAcute Leukemia of Ambiguous Lineage+5 more
M.D. Anderson Cancer Center 16
Testing effectiveness (Phase 2)UnknownNCT05066958
What this trial is testing

Ex-vivo Primed Memory Donor Lymphocyte Infusion to Boost Anti-viral Immunity After T-cell Depleted HSCT

Who this might be right for
Acute Myeloid LeukemiaHigh Risk Acute Myeloid LeukemiaAcute Lymphoblastic Leukemia, in Relapse+4 more
Federal Research Institute of Pediatric Hematology, Oncology and Immunology 20
Testing effectiveness (Phase 2)Looking for participantsNCT03779854
What this trial is testing

Naive T Cell Depletion for Preventing Chronic Graft-versus-Host Disease in Children and Young Adults With Blood Cancers Undergoing Donor Stem Cell Transplant

Who this might be right for
Acute Biphenotypic LeukemiaAcute LeukemiaAcute Leukemia of Ambiguous Lineage+14 more
Fred Hutchinson Cancer Center 68
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