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Results for “Moderate/Severe Respiratory Distress”

67 trials

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Showing 20 of 67 results

Large-scale testing (Phase 3)Ended earlyNCT04012073
What this trial is testing

Individualized Positive End-expiratory Pressure Guided by End-expiratory Lung Volume in the Acute Respiratory Distress Syndrome

Who this might be right for
Respiratory Distress Syndrome, Adult
Fondazione Policlinico Universitario Agostino Gemelli IRCCS 18
Not applicableNo Longer AvailableNCT04366830
What this trial is testing

Intermediate-size Expanded Access Program (EAP), Mesenchymal Stromal Cells (MSC) for Acute Respiratory Distress Syndrome (ARDS) Due to COVID-19 Infection

Who this might be right for
Moderate to Severe Acute Respiratory Distress Syndrome Associated With COVID-19
Mesoblast International Sàrl
Testing effectiveness (Phase 2)WithdrawnNCT05018975
What this trial is testing

Tazemetostat for the Treatment of Moderate to Severe COVID-19 Infection

Who this might be right for
COVID-19 Acute Respiratory Distress SyndromeCytokine Release Syndrome
Loma Linda University
Large-scale testing (Phase 3)Ended earlyNCT04371393
What this trial is testing

MSCs in COVID-19 ARDS

Who this might be right for
Mesenchymal Stromal CellsRemestemcel-LAcute Respiratory Distress Syndrome+1 more
Icahn School of Medicine at Mount Sinai 223
Very early researchLooking for participantsNCT07558538
What this trial is testing

A Single Dose, Dose Escalation Clinical Trial on the Safety, Tolerability and Efficacy of Lyophilized Powder for Inhalation of Recombinant Human Keratinocyte Growth Factor-2 (Rh-KGF-2) in The Treatment of Patients With Acute Respiratory Distress Syndrome

Who this might be right for
ARDS (Moderate or Severe)ARDS (Acute Respiratory Distress Syndrome)
Shanghai Zhongshan Hospital 24
Early research (Phase 1)WithdrawnNCT04490486
What this trial is testing

Umbilical Cord Tissue (UC) Derived Mesenchymal Stem Cells (MSCs) Versus Placebo to Treat Acute Pulmonary Inflammation Due to COVID-19

Who this might be right for
COVID-19Acute Respiratory Distress SyndromeCorona Virus Infection
Joshua M Hare
Not applicableStudy completedNCT03303807
What this trial is testing

Correction by ECCO2-R of Hypercapnia in Patients With DVP in Moderate to Severe ARDS Under Protective Ventilation.

Who this might be right for
Acute Respiratory Distress SyndromeHypercapnia
Assistance Publique - Hôpitaux de Paris 8
Testing effectiveness (Phase 2)UnknownNCT04760821
What this trial is testing

Prevention of Acute Myocardial Injury by Trimetazidine in Patients Hospitalized for COVID-19

Who this might be right for
Acute Respiratory Distress SyndromeCovid19Myocardial Injury
Ministry of Health, Brazil 80
Not applicableLooking for participantsNCT06430554
What this trial is testing

Personalized Ventilation Based on Ventilation-perfusion Mismatch and Lung Recruitability

Who this might be right for
Respiratory Distress SyndromePositive-Pressure RespirationMechanical Ventilation
Zhongda Hospital 40
Not applicableLooking for participantsNCT07362537
What this trial is testing

Enteral Nutrition Delivery in Prone Position Ventilated Patients With Moderate to Severe ARDS

Who this might be right for
ARDS
Southeast University, China 40
Testing effectiveness (Phase 2)UnknownNCT04977960
What this trial is testing

Efficacy of Canrenone as add-on Treatment in Moderate to Severe ARDS in COVID-19

Who this might be right for
COVID-19 Acute Respiratory Distress Syndrome
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico 180
Not applicableStudy completedNCT06146439
What this trial is testing

The Factors Causing Treatment Failure in Children Receiving Oxygen Therapy With High-flow Nasal Cannula

Who this might be right for
High-flow Nasal CannulaRespiratory DistressTreatment Failure
Dr. Behcet Uz Children's Hospital 201
Not applicableStudy completedNCT04325906
What this trial is testing

Early PP With HFNC Versus HFNC in COVID-19 Induced Moderate to Severe ARDS

Who this might be right for
Prone PositioningHigh Flow Nasal CannulaAcute Respiratory Distress Syndrome+1 more
Rush University Medical Center 224
Not applicableUnknownNCT05306392
What this trial is testing

Effects of Induced Moderate Hypothermia on ARDS Patients Under Venovenous ExtraCorporeal Membrane Oxygenation

Who this might be right for
ARDS, HumanExtracorporeal Membrane Oxygenation ComplicationHypothermia
Central Hospital, Nancy, France 30
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07567768
What this trial is testing

Continuous vs Bolus Neuromuscular Blockade Regimens in Moderate to Severe Hypoxemic Respiratory Failure and ARDS (COBRA)

Who this might be right for
ARDS (Acute Respiratory Distress Syndrome)
University of Calgary 100
Not applicableStudy completedNCT04156438
What this trial is testing

Airway Pressure Release Ventilation for Moderate-to-severe Acute Respiratory Distress Syndrome

Who this might be right for
Acute Respiratory Distress Syndrome
Saskatchewan Health Authority - Regina Area 1
Not applicableLooking for participantsNCT07284888
What this trial is testing

Practices of Prone Positioning Ventilation in Patients With Moderate-to-Severe ARDS in Intensive Care Units: A Registry-Based Observational Study

Who this might be right for
Acute Respiratory Distress Syndrome
Southeast University, China 1,000
Not applicableUnknownNCT05767125
What this trial is testing

Effect of APRV and LTV on Lung Ventilation and Perfusion in Patients With Moderate-to-severe ARDS

Who this might be right for
Acute Respiratory Distress Syndrome
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 40
Not applicableStudy completedNCT05736185
What this trial is testing

Effect of Electric Impedance Tomography-Guided PEEP Titration

Who this might be right for
ARDS, Human
Southeast University, China 69
Not applicableNot Yet RecruitingNCT07490925
What this trial is testing

Transpulmonary Pressure-guided Mechanical Ventilation Strategy in Right Ventricular Protection in Patients With ARDS

Who this might be right for
ARDS (Moderate or Severe)
Beijing Chao Yang Hospital 180
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