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Results for “Moderate Hepatic Insufficiency”

159 trials

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Showing 20 of 159 results

Early research (Phase 1)Study completedNCT01916993
What this trial is testing

Safety, Tolerability, and Pharmacokinetics of a Single Dose of NBI-98854 in Subjects With Mild,Moderate, or Severe Hepatic Insufficiency

Who this might be right for
Safety, Tolerability, and PK of NBI-98854 in Hepatically Impaired Subjects
Neurocrine Biosciences 24
Early research (Phase 1)Study completedNCT07102095
What this trial is testing

A Study Evaluating How Moderate Liver Impairment Affects the Absorption, Distribution, Metabolism, and Elimination of Sevabertinib After a Single Oral Dose

Who this might be right for
Hepatic InsufficiencyLiver DiseasesPharmacokinetics+1 more
Bayer 18
Early research (Phase 1)Not Yet RecruitingNCT07055412
What this trial is testing

Y-3 for Injection in Patients With Hepatic Insufficiency and Healthy Subjects

Who this might be right for
Pharmacokinetic DifferencesY-3Saftey+3 more
Neurodawn Pharmaceutical Co., Ltd. 24
Early research (Phase 1)Study completedNCT02871570
What this trial is testing

Evaluate the Effect of IV Doses of Rivipansel in Subjects With Moderate Hepatic Impairment and in Healthy Subjects With Normal Hepatic Function

Who this might be right for
Moderate Hepatic ImpairmentNormal Hepatic Function
GlycoMimetics Incorporated 16
Early research (Phase 1)Study completedNCT05409911
What this trial is testing

Assess S-217622 in Participants With Mild and Moderate Hepatic Impairment and Healthy Control Participants

Who this might be right for
Hepatic Impairment
Shionogi 25
Early research (Phase 1)Study completedNCT05882032
What this trial is testing

LY3502970 in Participants With Impaired and Normal Liver Function

Who this might be right for
HealthyHepatic Insufficiency
Eli Lilly and Company 29
Early research (Phase 1)Study completedNCT07248839
What this trial is testing

Assess the Drug Levels and Safety of BMS-986435 in Participants With Normal Hepatic Function and Participants With Different Degrees of Hepatic Impairment

Who this might be right for
Healthy VolunteersHepatic Impairment
Bristol-Myers Squibb 69
Early research (Phase 1)Study completedNCT02571816
What this trial is testing

Investigate the Effect of Hepatic Impairment on the Pharmacokinetics, Safety and Tolerability of ASP2215

Who this might be right for
Hepatic ImpairmentHealthy
Astellas Pharma Global Development, Inc. 24
Early research (Phase 1)Study completedNCT03626415
What this trial is testing

A Hepatic Impairment Study for PF-04965842.

Who this might be right for
Hepatic Impairment
Pfizer 24
Early research (Phase 1)Study completedNCT01298063
What this trial is testing

Influence of Mild and Moderate Hepatic Impairment on the Pharmacokinetics, Safety and Tolerability of Various Doses of Afatinib

Who this might be right for
Liver DiseasesHealthy
Boehringer Ingelheim 35
Early research (Phase 1)Study completedNCT03207425
What this trial is testing

EDP-305 in Subjects With Mild and Moderate Hepatic Impairment Compared With Normal Healthy Volunteers

Who this might be right for
NASH
Enanta Pharmaceuticals, Inc 29
Early research (Phase 1)Study completedNCT02171832
What this trial is testing

Single Dose of BI 1744 CL in Patients With Mild and Moderate Hepatic Impairment Compared to Subjects With Normal Hepatic Function

Who this might be right for
HealthyLiver Diseases
Boehringer Ingelheim 32
Early research (Phase 1)Study completedNCT06529796
What this trial is testing

Evaluation of the Pharmacokinetics and Safety of Inaxaplin in Participants With Mild or Moderate Hepatic Impairment

Who this might be right for
Focal Segmental Glomerulosclerosis (FSGS)
Vertex Pharmaceuticals Incorporated 36
Early research (Phase 1)Study completedNCT05560464
What this trial is testing

Evaluation of the Pharmacokinetics and Safety of VX-548 in Participants With Mild or Moderate Hepatic Impairment

Who this might be right for
Pain
Vertex Pharmaceuticals Incorporated 36
Early research (Phase 1)Study completedNCT01012284
What this trial is testing

TMC207 in Patients With Moderately Impaired Hepatic Function

Who this might be right for
Moderate Hepatic Impairment
Tibotec BVBA 16
Early research (Phase 1)Ended earlyNCT05126329
What this trial is testing

Pharmacokinetics of Amcenestrant in Female Hepatic Impaired Participants as Compared to Participants With Normal Hepatic Function

Who this might be right for
Hepatic Function Abnormal
Sanofi 13
Early research (Phase 1)Looking for participantsNCT07165002
What this trial is testing

The Pharmacokinetics and Safety of LY3537031 in Participants With Normal Liver Function and With Mild, Moderate, or Severe Liver Impairment

Who this might be right for
HealthyHepatic Insufficiency
Eli Lilly and Company 32
Early research (Phase 1)Study completedNCT06442436
What this trial is testing

Nemtabrutinib in Participants With Moderate Hepatic Impairment (MK-1026-015)

Who this might be right for
Hepatic Impairment (HI)
Merck Sharp & Dohme LLC 24
Early research (Phase 1)Study completedNCT01762462
What this trial is testing

Open Label Pharmacokinetic Study of SAR302503 in Subjects With Hepatic Impairment

Who this might be right for
Hepatic Impairment
Bristol-Myers Squibb 17
Early research (Phase 1)Study completedNCT01027169
What this trial is testing

Assess the Effect of Hepatic Impairment on Safinamide Pharmacokinetics

Who this might be right for
Hepatic Impairment
Newron Pharmaceuticals SPA 24
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