Testing effectiveness (Phase 2)UnknownNCT04217785What this trial is testingUmbilical Cord Serum Versus Conventional EyedropsWho this might be right forDry Eye Syndromes National University of Malaysia 102
Large-scale testing (Phase 3)Study completedNCT04633213What this trial is testingA Study Evaluating HBM9036 Efficacy and Safety on Moderate to Severe Dry EyeWho this might be right forDry Eye Harbour BioMed (Guangzhou) Co. Ltd. 577
Testing effectiveness (Phase 2)Study completedNCT00128245What this trial is testingSafety and Efficacy of Pimecrolimus Ophthalmic Suspension in Patients With Moderate to Severe Keratoconjunctivitis SiccaWho this might be right forKeratoconjunctivitis Sicca Novartis 440
Testing effectiveness (Phase 2)Looking for participantsNCT07413172What this trial is testingAutologous Serum Tears With Hyaluronate vs Balanced Salt Solution for Moderate-to-Severe Dry EyeWho this might be right forDry EyeEye DiseasesEyes Dry Chronic University of Miami 20
Large-scale testing (Phase 3)Study completedNCT04541888What this trial is testingAssess the Safety and Efficacy of CsA Ophthalmic Gel in Subjects With Moderate to Severe Dry Eye DiseaseWho this might be right forDry Eye Zhaoke (Guangzhou) Ophthalmology Pharmaceutical Ltd. 644
Not applicableStudy completedNCT03830359What this trial is testingEfficacy, Safety of T2769 in Dry Eye DiseaseWho this might be right forDry Eye Syndrome Laboratoires Thea 62
Not applicableStudy completedNCT02980913What this trial is testingDifference in the Frequency of Use of Lachrymal Substitutes in Patients With Moderate to Severe Dry Eye SyndromeWho this might be right forDry Eye Syndromes Medical University of Vienna 45
Testing effectiveness (Phase 2)Study completedNCT04084483What this trial is testingA Study Assessing the Safety, Efficacy, and Optimum Dosage of K-161 in Subjects With Moderate to Severe Dry Eye DiseaseWho this might be right forDry Eye Disease Kowa Research Institute, Inc. 238
Large-scale testing (Phase 3)Active Not RecruitingNCT06741969What this trial is testingNipocalimab in Moderate to Severe Sjogren's DiseaseWho this might be right forSjogrens Syndrome Janssen Research & Development, LLC 655
Early research (Phase 1)UnknownNCT05618730What this trial is testingSafety, Tolerability, Plug Retention and Preliminary Efficacy of Tacrolimus-loaded Punctal Plug in Patients With Moderate to Severe Dry Eye Disease - Cohort BWho this might be right forDry EyeKeratoconjunctivitis SiccaOcular Inflammation Eximore Ltd. 20
Post-approval studies (Phase 4)Study completedNCT02986750What this trial is testingInfluence of Three Different Formulations of Lachrymal Substitutes on Tear Film Thickness and Other Signs and Symptoms in Patients With Moderate to Severe Dry Eye SyndromeWho this might be right forDry Eye Syndromes Medical University of Vienna 120
Large-scale testing (Phase 3)Study completedNCT00814515What this trial is testingDouble-Masked Trial of NOVA22007 (Ciclosporin 0.1%) Versus Vehicle in Patients With Moderate to Severe Dry Eye SyndromeWho this might be right forModerate to Severe Dry Eye Syndrome Santen SAS 482
Post-approval studies (Phase 4)Looking for participantsNCT06964269What this trial is testingUse of Acthar Gel Single-Dose Pre-Filled SelfJectTM Injector in Patients With Moderate-Severe Keratitis and Autoimmune DiseaseWho this might be right forAutoimmune DiseasesDry EyeNeurotrophic Keratitis Toyos Clinic 20
Post-approval studies (Phase 4)Study completedNCT04127851What this trial is testingEvaluating HA 0.15% Compared With Cyclosporine 0.05%, and Efficacy of Combination Therapy in Dry Eye Disease PatientsWho this might be right forDry EyeDry Eye Syndromes Taejoon Pharmaceutical Co., Ltd. 438
Testing effectiveness (Phase 2)Study completedNCT04645446What this trial is testingSafety and Efficacy of Two Different Concentrations (0.5% and 1%) of Progesterone Topical Gel Compared to Placebo in Patients Diagnosed With Moderate to Severe Dry Eye SyndromeWho this might be right forDry Eye Disease SIFI SpA 96
Post-approval studies (Phase 4)UnknownNCT00704275What this trial is testingComparison of Efficacy, Safety and Anti-Inflammatory Effect Between Topical 0.05%Cyclosporine A Emulsion and REFRESH® in Patients With Moderate to Severe Dry EyesWho this might be right forDry Eye Chulalongkorn University 60
Testing effectiveness (Phase 2)Study completedNCT00679718What this trial is testingINS365 Ophthalmic Solution in Patients With Moderate to Severe Dry Eye DiseaseWho this might be right forDry Eye Disease Merck Sharp & Dohme LLC 150
Post-approval studies (Phase 4)UnknownNCT04775303What this trial is testingA Clinical Trial to Evaluate the Clinical Efficacy of Cyclosporine 0.1% (Ikervis®) for Moderate to Severe Dry Eye Patients. (IKE-03-SWITCHING)Who this might be right forModerate to Severe Dry Eye Yonsei University 90
Large-scale testing (Phase 3)Not Yet RecruitingNCT06903611What this trial is testingPhase III Study of Topical Fibrinogen-Depleted Human Platelet Lysate Compared to Placebo for Moderate to Severe Dry EyeWho this might be right forDry Eye DiseaseDry EyeDry Eyes Chronic+1 more Cambium Bio Limited 475
Post-approval studies (Phase 4)Study completedNCT02585453What this trial is testingInfluence of Lachrymal Substitute Gels on Tear Film Thickness in Patients With Moderate to Severe Dry Eye SyndromeWho this might be right forDry Eye Syndromes Medical University of Vienna 60